Results 121 to 130 of about 28,926,907 (345)

Joint Modeling of Longitudinal Visual Field Changes and Time to Detect Progression in Glaucoma Patients: A Secondary Data Analysis [PDF]

open access: yesIranian Journal of Medical Sciences
Background: Glaucoma causes irreversible damage to the optic nerve and can lead to blindness if it is not treated appropriately. Evaluation of longitudinal changes in the visual field (VF) and detecting progression in a timely manner are critical for ...
Samaneh Sabouri   +6 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Survival analysis of female breast cancer patients in Panyu District

open access: yes预防医学
Objective: To investigate the survival rate of female breast cancer patients in Panyu District, Guangzhou City, so as to provide the basis for improving the prognosis of breast cancer patients. Methods: Basic information including age, clinical stage and
YOU Na, LIANG Xiaoxian, LAI Chunyan, RUAN Huihong
doaj   +1 more source

Impact of aspirin and statins on long‐term survival in patients hospitalized with acute myocardial infarction complicated by heart failure: an analysis of 1706 patients [PDF]

open access: bronze, 2013
Christian Lewinter   +8 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

TIME TO RECOVERY FROM COVID-19 AMONG PATIENTS IN SIDOARJO REGENCY, EAST JAVA PROVINCE, INDONESIA IN 2022

open access: yesJurnal Berkala Epidemiologi
Background: The SARS-CoV-2 mutation in the bodies of COVID-19 patients is a critical factor for health. Notably, in October 2022, the disease recovery rate in Sidoarjo (96.05%) was lower than the national rate (97.30%).
Noer Farakhin   +3 more
doaj   +1 more source

Improved Mixture Cure Model Using Machine Learning Approaches

open access: yesMathematics
The mixture cure model has been widely used in medicine, public health, and bioinformatics. The traditional mixture cure model has limitations in model flexibility and handling complex structured data and big data.
Huina Wang, Tian Feng, Baosheng Liang
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

A comparative study of methods for dynamic survival analysis

open access: yesFrontiers in Neurology
IntroductionDynamic survival analysis has become an effective approach for predicting time-to-event outcomes based on longitudinal data in neurology, cognitive health, and other health-related domains.
Wieske K. de Swart   +3 more
doaj   +1 more source

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