Results 121 to 130 of about 4,850,533 (302)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Radiomics-based decision support tool with ground-glass opacity status of 5-year survival prediction for early-stage non-small cell lung cancer

Reports of Practical Oncology and Radiotherapy
BACKGROUND: To evaluate the predictive performance differences for postoperative 5-year survival risk for early-stage non-small cell lung cancer (NSCLC) patients with two image analysis methods based on ground-glass opacity (GGO) status and radiomics ...
Reo Isobe, Daisuke Kawahara, Nobuki Imano, Ikuno Nishibuchi, Yuji Murakami   +4 more
doaj   +1 more source

From Cancer to Transplantation: An Evaluation of Period Analysis for Calculating Up-to-date Long-term Survival Estimates [PDF]

, 2010
Ádám Gondos, Bernd Doehler, Gerhard Opelz, Hermann Brenner   +3 more
openalex   +1 more source

Analysis of Survival Data by a Weibull-generalized Sibuya Distribution

, 2022
Fatmah Almathkour, M. E. Ghitany, Ramesh C. Gupta, J. Mazucheli   +3 more
openalex   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A California Cancer Registry Analysis of Urothelial and Non-urothelial Bladder Cancer Subtypes: Epidemiology, Treatment, and Survival

, 2020
Jeremy Martin, Francis A. Jefferson, Melissa Huang, John Sung, Jenny Chang, Keyhan Piranviseh, Argyrios Ziogas, Hoda Anton‐Culver, Ramy F. Youssef   +8 more
openalex   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Perform tumor-specific survival analysis for Merkel cell carcinoma patients undergoing surgical resection based on the SEER database by constructing a nomogram chart

Open Medicine
To explore the postoperative risk factors of Merkel cell carcinoma patients who have undergone surgical resection, and to construct a survival prognosis column chart.
Zhou Jingxuan, Yu Hai, Xia Xichun, Chen Yanan, Ming Wai-kit, Jiang Yuzhen, Lak Yau Sun, Ip Chongchong, Huang Chaodi, Zhao Qiqi, Zheng Suzheng, Xia Liming, Zheng Xinkai, Wu Shi, Lyu Jun, Deng Liehua   +15 more
doaj   +1 more source

Outcomes in end-stage renal disease dialysis patients with depression

BJPsych Open
Background Depression is the most common psychiatric disorder among patients with end-stage renal disease (ESRD), yet the risk factors for mortality in this population remain unclear.
I-Ning Yang, Chin-Li Lu, Jhi-Joung Wang, Ming-Chuan Hung, Chih-Chiang Chien   +4 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source