Results 81 to 90 of about 28,926,907 (345)

Palliative stenting for oesophagogastric cancer: tumour and host factors and prognosis [PDF]

, 2018
Objectives: Palliative self-expandable metallic stent (SEMS) insertion is common in patients not suitable for resection of oesophagogastric (OG) cancer. Factors which may determine survival, however, are not clear.
Glen, Paul, McMillan, Donald C., Park, James H., Woodley, Niall   +3 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Construction and Identification of an NLR-Associated Prognostic Signature Revealing the Heterogeneous Immune Response in Skin Cutaneous Melanoma

Clinical, Cosmetic and Investigational Dermatology, 2023
Yi Geng,1 Yu-Jie Sun,1 Hao Song,1 Qiu-Ju Miao,1 Yi-Fei Wang,1 Jin-Liang Qi,2 Xiu-Lian Xu,1 Jian-Fang Sun1 1Institute of Dermatology, Peking Union Medical College and Chinese Academy of Medical Sciences, Nanjing, 210042, People’s Republic of China; 2State
Geng Y, Sun YJ, Song H, Miao QJ, Wang YF, Qi JL, Xu XL, Sun JF   +7 more
doaj  

Kit receptor tyrosine kinase dysregulations in feline splenic mast cell tumours [PDF]

, 2017
This study investigated Ki t receptor dysregulations (cytoplasmic immunohistochemical expression and/or c-KIT mutations) in cats a\ufb00ected with splenic mast cell tumours. Twenty-two cats were included.
Amagai, Arock, Carpenter, Columbo, Dank, Frost, Garner, Giantin, Hadzijusufovic, Hahn, Henry, Isotani, Isotani, Lanternier, Letard, Liska, Litster, London, London, Mallett, Marconato, Meininger, Rodriguez-Cariño, Sabattini, Sabattini, Sabattini, Spangler, Takanosu, Takeuchi, Webster, Webster, Webster, Zemke   +32 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

ENDORSE: a prognostic model for endocrine therapy in estrogen‐receptor‐positive breast cancers

Molecular Systems Biology, 2022
Advanced and metastatic estrogen receptor‐positive (ER+) breast cancers are often endocrine resistant. However, endocrine therapy remains the primary treatment for all advanced ER+ breast cancers.
Aritro Nath, Adam L Cohen, Andrea H Bild
doaj   +1 more source

IDDF2021-ABS-0020 A survival analysis of chinese patients with gastrointestinal mucosal melanomas: a single-center retrospective study [PDF]

, 2021
Junrong Chen, Jiachen Sun, Jiayao Huang
openalex   +1 more source

A Model for the Analysis of Caries Occurrence in Primary Molar Tooth Surfaces [PDF]

, 2012
Recently methods of caries quantification in the primary dentition have moved away from summary ‘whole mouth’ measures at the individual level to methods based on generalised linear modelling (GLM) approaches or survival analysis approaches. However, GLM
Baelum V, Beck J, Bower E, Burnside G, Burnside G, Fejerskov O, Gilthorpe M, Gilthorpe M, Gilthorpe M, Hannigan A, Hopcraft M, Hujoel P, J. Stephenson, James P, Jones C, Leroy R, Leroy R, Levine R, Lindsey J, Mancl L, Mejare I, Pitts N, Ramirez O, Riley J, Rodrigues C, Selwitz R, Stephenson J, Stephenson J, Tickle M, Vanobbergen J   +29 more
core   +1 more source

CapSurv: Capsule Network for Survival Analysis With Whole Slide Pathological Images

IEEE Access, 2019
Survival analysis is a branch of statistics to analyze the time duration that is expected until some events of interest happen, like the death in the organisms of biology.
Bo Tang, Ao Li, Bin Li, Minghui Wang
semanticscholar   +1 more source