Results 81 to 90 of about 4,736,557 (326)

Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. [PDF]

open access: yes, 2015
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with a dismal prognosis. However, while most patients die within the first year of diagnosis, very rarely, a few patients can survive for >10 years.
Brentnall, Teresa A   +15 more
core   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Joint modeling of longitudinal change in tumor cell level and time to death of breast cancer patients: In case of Ayder comprehensive specialized Hospital Tigray, Ethiopia

open access: yesCogent Medicine, 2021
: Breast cancer is the major public health problem throughout the world and it results in serious physical damages and death. This work proposes the use of joint model to study breast cancer in patients of Ayder Hospital.
Bsrat Tesfay   +2 more
doaj   +1 more source

Survival Seq2Seq: A Survival Model based on Sequence to Sequence Architecture [PDF]

open access: yesarXiv, 2022
This paper introduces a novel non-parametric deep model for estimating time-to-event (survival analysis) in presence of censored data and competing risks. The model is designed based on the sequence-to-sequence (Seq2Seq) architecture, therefore we name it Survival Seq2Seq.
arxiv  

Survival Analysis [PDF]

open access: yes, 2022
Survival analysis is a branch of statistics used by engineers to estimate the reliability of some mechanical system before it ultimately fails. In particular, survival analysis is used to estimate the lifespan of consumer goods.
Charles, Darrell
core   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

icenReg: Regression Models for Interval Censored Data in R

open access: yesJournal of Statistical Software, 2017
The non-parametric maximum likelihood estimator and semi-parametric regression models are fundamental estimators for interval censored data, along with standard fullyparametric regression models.
Clifford Anderson-Bergman
doaj   +1 more source

Survival Mixture Density Networks [PDF]

open access: yesarXiv, 2022
Survival analysis, the art of time-to-event modeling, plays an important role in clinical treatment decisions. Recently, continuous time models built from neural ODEs have been proposed for survival analysis. However, the training of neural ODEs is slow due to the high computational complexity of neural ODE solvers.
arxiv  

Multivariate Survival Mixed Models for Genetic Analysis of Longevity Traits [PDF]

open access: yes, 2014
A class of multivariate mixed survival models for continuous and discrete time with a complex covariance structure is introduced in a context of quantitative genetic applications.
Labouriau, Rodrigo   +2 more
core   +2 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

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