Results 111 to 120 of about 3,364,430 (292)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Standard distributions must be improved to enhance their capacity for data modeling because they do not inherently suit all sorts of data sets in an acceptable manner.
Tabassum Naz Sindhu +4 more
doaj +1 more source
Survival and Function of Islets during Culture
Cell and tissue culture techniques have improved considerably since the first attempts to maintain explants of animal tissue in vitro. The two major developments that have allowed these improvements are the ability to produce continuous cell lines, thus ...
Heather A. Clayton, Nick J.M. London
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Comparative Survival Function in Patients with Positive Surgical Margins Following Laryngectomy. [PDF]
Özkul Y +6 more
europepmc +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Asymmetric Dimethylation of Ribosomal S6 Kinase 2 Regulates Its Cellular Localisation and Pro-Survival Function. [PDF]
Khalil MI +6 more
europepmc +1 more source
Nonparametric estimation: The survival function
The unknown survival function S(t) of a random variable T = 0 is considered. First we study the properties of S(t) and then, we estimate it from a Bayesian point of view. We compare the estimator with the posterior mean and we finish giving Bayes rules for linear functions of S(t).
openaire +2 more sources
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
The Exponentiated Power Generalized Weibull: Properties and Applications
We propose a new lifetime model called the exponentiated power generalized Weibull (EPGW) distribution, which is obtained from the exponentiated family applied to the power generalized Weibull (PGW) distribution.
FERNANDO A. PEÑA-RAMÍREZ +3 more
doaj +1 more source

