Results 31 to 40 of about 561,319 (304)

Prognostic Significance of Gene Signature of Tertiary Lymphoid Structures in Patients With Lung Adenocarcinoma

Frontiers in Oncology, 2021
BackgroundLung adenocarcinoma (LUAD) is a highly mortal cancer. Tertiary lymphoid structures (TLS) are ectopic lymphoid organs with similar morphological and molecular characters to secondary lymphoid organ.
Hong Feng, Hong Feng, Fujun Yang, Lihong Qiao, Kai Zhou, Kai Zhou, Junfei Wang, Jiao Zhang, Tian Tian, Ying Du, Hong Shangguan   +10 more
doaj   +1 more source

Dynamic stress–strength reliability estimation of system with survival signature

Statistical Theory and Related Fields, 2018
In this paper, we proposed a dynamic stress–strength model for coherent system. It is supposed that the system consists of n components with initial random strength and each component is subjected to random stresses.
Yiming Liu, Yimin Shi, Xuchao Bai, Bin Liu   +3 more
doaj   +1 more source

Development of an Immune-Related Prognostic Signature in Breast Cancer

Frontiers in Genetics, 2020
BackgroundAlthough increased early detection, diagnosis and treatment have improved the outcome of breast cancer patients, prognosis estimation still poses challenges due to the disease heterogeneity.
Peiling Xie, Yuying Ma, Shibo Yu, Rui An, Jianjun He, Huimin Zhang   +5 more
doaj   +1 more source

Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome [PDF]

, 2018
Background: Genetic classification of breast cancer based on the coding mRNA suggests the evolution of distinct subtypes. Whether the non-coding genome is altered concordantly with the coding genome and the mechanism by which the cell cycle directly ...
Addya, Sankar, Casimiro, Mathew C., Deng, Shengqiong, DiSante, Gabriele, Dong, Lin, Ertel, Adam, Gormley, Michael, Ju, Xiaoming, Li, Qinchuan, Pestell, Richard G., Pestell, Timothy G., Qiao, Jing, Tozeren, Ayden, Wang, Guangxue, Wang, Min, Yu, Zuoren, Zhao, Qian   +16 more
core   +2 more sources

Network Signatures of Survival in Glioblastoma Multiforme

PLoS Computational Biology, 2013
To determine a molecular basis for prognostic differences in glioblastoma multiforme (GBM), we employed a combinatorial network analysis framework to exhaustively search for molecular patterns in protein-protein interaction (PPI) networks. We identified a dysregulated molecular signature distinguishing short-term (survival635 days) survivors of GBM ...
Vishal N Patel, Giridharan Gokulrangan, Salim A Chowdhury, Yanwen Chen, Andrew E Sloan, Mehmet Koyutürk, Jill Barnholtz-Sloan, Mark R Chance   +7 more
openaire   +4 more sources

Radiomics signature of computed tomography imaging for prediction of survival and chemotherapeutic benefits in gastric cancerResearch in context

EBioMedicine, 2018
To develop and validate a radiomics signature for the prediction of gastric cancer (GC) survival and chemotherapeutic benefits. In this multicenter retrospective analysis, we analyzed the radiomics features of portal venous-phase computed tomography in ...
Yuming Jiang, Chuanli Chen, Jingjing Xie, Wei Wang, Xuefan Zha, Wenbing Lv, Hao Chen, Yanfeng Hu, Tuanjie Li, Jiang Yu, Zhiwei Zhou, Yikai Xu, Guoxin Li   +12 more
doaj   +1 more source

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures [PDF]

, 2011
Background: Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers.
Karn, Thomas, Pusztai, Lajos, Holtrich, Uwe, Iwamoto, Takayuki, Shiang, Christine Y., Schmidt, Marcus, Müller, Volkmar, Solbach, Christine, Gätje, Regine, Hanker, Lars, Ahr, André, Liedtke, Cornelia, Ruckhäberle, Eugen, Kaufmann, Manfred, Rody, Achim   +14 more
core   +1 more source

Measurement of the Total Active 8B Solar Neutrino Flux at the Sudbury Neutrino Observatory with Enhanced Neutral Current Sensitivity [PDF]

, 2003
The Sudbury Neutrino Observatory (SNO) has precisely determined the total active (nu_x) 8B solar neutrino flux without assumptions about the energy dependence of the nu_e survival probability.
A. B. McDonald, A. Bellerive, A. D. Marino, A. E. Anthony, A. Hime, A. J. Noble, A. L. Hallin, A. S. Hamer, A. V. Krumins, A. W. P. Poon, B. A. Moffat, B. C. Robertson, B. G. Fulsom, B. G. Nickel, B. L. Wall, B. T. Cleveland, C. A. Duba, C. C. M. Kyba, C. E. Okada, C. E. Waltham, C. J. Sims, C. J. Virtue, C. K. Hargrove, C. Mifflin, C. Ouellet, C. W. Nally, D. L. Wark, D. R. Grant, D. Sinclair, D. Waller, E. B. Norman, E. D. Earle, E. D. Hallman, E. Rollin, E. W. Beier, F. A. Duncan, F. Dalnoki-Veress, F. Fleurot, G. A. Cox, G. Doucas, G. G. Miller, G. McGregor, G. T. Ewan, G. Tešić, H. B. Mak, H. C. Evans, H. Fergani, H. Labranche, H. Wan Chan Tseung, I. Levine, I. T. Lawson, J. A. Dunmore, J. A. Formaggio, J. B. Wilhelmy, J. Boger, J. C. Hall, J. F. Wilkerson, J. Farine, J. Heise, J. J. Simpson, J. L. Orrell, J. Law, J. M. Wouters, J. Maneira, J. R. Klein, J. R. Leslie, J. R. Wilson, J. N. Bahcall, K. Frame, K. Graham, K. K. S. Miknaitis, K. M. Heeger, K. T. Lesko, K. Zuber, L. C. Stonehill, M. A. Howe, M. Chen, M. Dunford, M. G. Boulay, M. G. Bowler, M. H. Schwendener, M. M. Fowler, M. R. Dragowsky, M. S. Kos, M. Thomson, M. Thorman, M. W. E. Smith, M. Yeh, N. A. Jelley, N. Gagnon, N. McCauley, N. S. Oblath, N. Starinsky, N. West, O. Simard, P. J. Doe, P. J. Harvey, P. Jagam, P. Skensved, R. G. H. Robertson, R. G. Stokstad, R. G. Van de Water, R. Hazama, R. J. Hemingway, R. L. Hahn, R. L. Helmer, R. Lange, R. MacLellan, R. S. Dosanjh, R. Tafirout, R. Van Berg, R. W. Ollerhead, S. D. Biller, S. J. Brice, S. J. M. Peeters, S. Luoma, S. M. Oser, S. Majerus, S. McGee, S. N. Ahmed, S. R. Elliott, S. S. E. Rosendahl, S. P. Mikheyev, T. J. Bowles, T. Kirsten, T. Kutter, T. V. Bullard, V. L. Rusu, W. B. Handler, W. J. Heintzelman, X. Chen, X. Dai, Y. D. Chan, Y. Takeuchi, Z. Maki   +134 more
core   +3 more sources

A glycosylation-related signature predicts survival in pancreatic cancer

Aging, 2023
Tumor initiation and progression are closely associated with glycosylation. However, glycosylated molecules have not been the subject of extensive studies as prognostic markers for pancreatic cancer. The objectives of this study were to identify glycosylation-related genes in pancreatic cancer and use them to construct reliable prognostic models.The ...
Hu, Huidong, He, Bingsheng, He, Mingang, Tao, Hengmin, Li, Baosheng   +4 more
openaire   +2 more sources

Identification of an amino acid metabolism-associated gene signature predicting the prognosis and immune therapy response of clear cell renal cell carcinoma

Frontiers in Oncology, 2022
BackgroundThe upregulation of amino acid metabolism is an essential form of metabolic reprogramming in cancer. Here, we developed an amino acid metabolism signature to predict prognosis and anti-PD-1 therapy response in clear cell renal cell carcinoma ...
Fan Zhang, Junyu Lin, Daiwen Zhu, Yongquan Tang, Yiping Lu, Zhihong Liu, Xianding Wang   +6 more
doaj   +1 more source