Results 11 to 20 of about 561,319 (304)

MicroRNA Signature Predicts Survival and Relapse in Lung Cancer [PDF]

Cancer Cell, 2008
We investigated whether microRNA expression profiles can predict clinical outcome of NSCLC patients. Using real-time RT-PCR, we obtained microRNA expressions in 112 NSCLC patients, which were divided into the training and testing sets. Using Cox regression and risk-score analysis, we identified a five-microRNA signature for the prediction of treatment ...
Yu, S-L, Chen, H-Y, Chang, G-C, Chen, C-Y, Chen, H-W, Singh, S, Cheng, C-L, Yu, C-J, Lee, Y-C, Chen, H-S, Su, T-J, Chiang, C-C, Li, H-N, Hong, Q-S, Su, H-Y, Chen, C-C, Chen, W-J, Liu, C-C, Chan, W-K, Chen, WJ, Li, K-C, Chen, JJW, Yang, P-C   +22 more
openaire   +5 more sources

Fatigue Reliability Analysis of Wind Turbine Drivetrain Considering Strength Degradation and Load Sharing Using Survival Signature and FTA

Energies, 2020
The wind turbine drivetrain suffers significant impact loads that severely affect the reliability and safety of wind turbines. Bearings and gears within the drivetrain are critical components with high repair costs and lengthy downtime.
Yao Li, Caichao Zhu, Xu Chen, Jianjun Tan   +3 more
doaj   +1 more source

A lipocalin sequence signature modulates cell survival [PDF]

FEBS Letters, 2010
Lipocalins are β‐barrel proteins, which share three conserved motifs in their amino acid sequence. In this study, we identified by a peptide mapping approach, a seven‐amino acid sequence related to one of these motifs (motif 2) that modulates cell survival.
Chudzinski-Tavassi, Ana Marisa, Carrijo-Carvalho, Linda C., Waismam, Kaline, Farsky, Sandra H.P., Ramos, Oscar H.P., Reis, Cleyson V.   +5 more
openaire   +2 more sources

Gene signature to predict prognostic survival of hepatocellular carcinoma [PDF]

Open Medicine, 2022
Abstract Hepatocellular carcinoma (HCC) has a high incidence and poor prognosis and is the second most fatal cancer, and certain HCC patients also show high heterogeneity. This study developed a prognostic model for predicting clinical outcomes of HCC.
Li Li, Cao Yundi, Fan YingRui, Li Rong
openaire   +3 more sources

Survival prediction and response to immune checkpoint inhibitors: A prognostic immune signature for hepatocellular carcinoma

Translational Oncology, 2021
Hepatocellular carcinoma (HCC) is one of the most common cancers all over the world. Several studies have explored if immune-related genes and tumor immune microenvironment could play roles in HCC prognoses. This study is aimed at developing a prognostic
Ying Xu, Zheng Wang, Fufeng Li
doaj   +1 more source

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma [PDF]

, 2015
Accurate assessment of neuroblastoma outcome prediction remains challenging. Therefore, this study aims at establishing novel prognostic tumor DNA methylation biomarkers.
, Berbegall, Ana P., Bienertova-Vasku, Julie, Bown, Nick, Cannoodt, Robrecht, Clément, Nathalie, Combaret, Valérie, De Preter, Katleen, De Wilde, Bram, Decock, Anneleen, Haber, Michelle, Hoyoux, Claire, Laureys, Geneviève, Murray, Jayne, Noguera, Rosa, Ongenaert, Maté, Pierron, Gaelle, Schleiermacher, Gudrun, Schulte, Johannes H., Speleman, Frank, Stallings, Ray L., Tweddle, Deborah A., Van Roy, Nadine, Vandesompele, Jo, Verniers, Kimberly   +24 more
core   +5 more sources

Comprehensive Analysis of an Individualized Immune-Related lncRNA Pair Signature in Gastric Cancer

Frontiers in Cell and Developmental Biology, 2022
Long noncoding RNAs (lncRNAs) have diverse functions, including immune regulation. Increasing studies have reported immune-related lncRNAs in the prognosis of multiple cancers.
Chuang Nie, Jiabao Zhai, Qi Wang, Xiaojie Zhu, Guanghui Xiang, Chang Liu, Tianyu Liu, Wanyu Wang, Yimin Wang, Yashuang Zhao, Wenjing Tian, Yingwei Xue, Haibo Zhou   +12 more
doaj   +1 more source

Establishment and external verification of an oxidative stress-related gene signature to predict clinical outcomes and therapeutic responses of colorectal cancer

Frontiers in Pharmacology, 2023
Objective: Accumulated evidence highlights the biological significance of oxidative stress in tumorigenicity and progression of colorectal cancer (CRC).
Sha Cao, Cheng Chen, Dezhi Gu, Zhengdong Wang, Guanghui Xu   +4 more
doaj   +1 more source

Identification of miRNA signatures associated with radiation-induced late lung injury in mice. [PDF]

, 2020
Acute radiation exposure of the thorax can lead to late serious, and even life-threatening, pulmonary and cardiac damage. Sporadic in nature, late complications tend to be difficult to predict, which prompted this investigation into identifying non ...
Iwamoto, Keisuke S, Lee, Jason T, Lukaszewicz, Agnes I, McBride, William H, Menon, Naresh, Micewicz, Ewa D, Miller, Thomas A, Nguyen, Christine, Olafsen, Tove, Ratikan, Josephine A, Rogers, Claude J, Schaue, Dörthe, Starbird, Mark A, Yamada-Hanff, Jason   +13 more
core   +1 more source

Immunological network signatures of cancer progression and survival [PDF]

BMC Medical Genomics, 2011
The immune contribution to cancer progression is complex and difficult to characterize. For example in tumors, immune gene expression is detected from the combination of normal, tumor and immune cells in the tumor microenvironment. Profiling the immune component of tumors may facilitate the characterization of the poorly understood roles immunity plays
Trevor Clancy1*, Marco Pedicini2, Filippo Castiglione2, Daniele Santoni2, Vegard Nygaard1, Timothy J Lavelle1, Mikael Benson3, Eivind Hovig4, 1, 5   +9 more
openaire   +10 more sources