Results 21 to 30 of about 561,319 (304)

Development of a Prognostic Five-Gene Signature for Diffuse Lower-Grade Glioma Patients

Frontiers in Neurology, 2021
Background: Diffuse lower-grade gliomas (LGGs) are infiltrative and heterogeneous neoplasms. Gene signature including multiple protein-coding genes (PCGs) is widely used as a tumor marker.
Qiang Zhang, Wenhao Liu, Shun-Bin Luo, Fu-Chen Xie, Xiao-Jun Liu, Ren-Ai Xu, Lixi Chen, Zhilin Su   +7 more
doaj   +1 more source

CpG Site-Based Signature Predicts Survival of Colorectal Cancer

Biomedicines, 2022
Background: A critical unmet medical need in clinical management of colorectal cancer (CRC) pivots around lack of noninvasive and or minimally invasive techniques for early diagnosis and prognostic prediction of clinical outcomes. Because DNA methylation can capture the regulatory landscape of tumors and can be measured in body fluids, it provides ...
Jiande Wu, Lu Zhang, Aditi Kuchi, David Otohinoyi, Chindo Hicks   +4 more
openaire   +3 more sources

Development of a Four-mRNA Expression-Based Prognostic Signature for Cutaneous Melanoma

Frontiers in Genetics, 2021
We aim to find a biomarker that can effectively predict the prognosis of patients with cutaneous melanoma (CM). The RNA sequencing data of CM was downloaded from The Cancer Genome Atlas (TCGA) database and randomly divided into training group and test ...
Haiya Bai, Youliang Wang, Huimin Liu, Junyang Lu   +3 more
doaj   +1 more source

Marginal and joint reliability importance based on survival signature [PDF]

Reliability Engineering & System Safety, 2018
Abstract Marginal and joint reliability importance measures have been found to be useful in optimal system design. Various importance measures have been defined and studied for a variety of system models. The results in the literature are mostly based on the assumption that the components within the system are independent or identical.
Eryilmaz, S., Coolen, F.P.A., Coolen-Maturi, T.   +2 more
openaire   +4 more sources

Tumor microenvironment related novel signature predict lung adenocarcinoma survival

PeerJ, 2021
Background Lung adenocarcinoma (LUAD) is the most common histological type of lung cancers, which is the primary cause of cancer‐related mortality worldwide. Growing evidence has suggested that tumor microenvironment (TME) plays a pivotal role in tumorigenesis and progression.
Chen, Juan, Zhou, Rui
openaire   +2 more sources

A Gene Signature Identifying CIN3 Regression and Cervical Cancer Survival [PDF]

Cancers, 2021
The purpose of this study was to establish a gene signature that may predict CIN3 regression and that may aid in selecting patients who may safely refrain from conization. Oncomine mRNA data including 398 immune-related genes from 21 lesions with confirmed regression and 28 with persistent CIN3 were compared.
Mari K. Halle, Ane Cecilie Munk, Birgit Engesæter, Saleha Akbari, Astri Frafjord, Erling A. Hoivik, David Forsse, Kristine E. Fasmer, Kathrine Woie, Ingfrid S. Haldorsen, Bjørn I. Bertelsen, Emiel A. M. Janssen, Einar Gudslaugsson, Camilla Krakstad, Irene T. Øvestad   +14 more
openaire   +4 more sources

Simulation methods for system reliability using the survival signature [PDF]

Reliability Engineering & System Safety, 2017
Recently, the survival signature has been presented as a summary of the structure function which is sufficient for computation of common reliability metrics and has the crucial advantage that it can be applied to systems with components whose failure times are not exchangeable. The survival signature provides a huge reduction in required information, e.
Patelli, Edoardo, Feng, Geng, Coolen, Frank P.A., Coolen-Maturi, Tahani   +3 more
openaire   +5 more sources

Transcriptomic Analysis of Glycolysis-Related Genes Reveals an Independent Signature of Bladder Carcinoma

Frontiers in Genetics, 2020
BackgroundBladder carcinoma (BC) is one of the most prevalent and malignant tumors. Multiple gene signatures based on BC metabolism, especially regarding glycolysis, remain unclear. Thus, we developed a glycolysis-related gene signature to be used for BC
Zezhong Mou, Zezhong Mou, Chen Yang, Chen Yang, Chen Yang, Zheyu Zhang, Zheyu Zhang, Siqi Wu, Siqi Wu, Chenyang Xu, Chenyang Xu, Zhang Cheng, Zhang Cheng, Xiyu Dai, Xiyu Dai, Xinan Chen, Xinan Chen, Yuxi Ou, Yuxi Ou, Haowen Jiang, Haowen Jiang, Haowen Jiang   +21 more
doaj   +1 more source

Somatic mutation load of estrogen receptor-positive breast tumors predicts overall survival: an analysis of genome sequence data. [PDF]

, 2014
Breast cancer is one of the most commonly diagnosed cancers in women. While there are several effective therapies for breast cancer and important single gene prognostic/predictive markers, more than 40,000 women die from this disease every year.
Bainbridge, Matthew N, Brown, Powel H, Haricharan, Svasti, Scheet, Paul   +3 more
core   +1 more source

Reliability Equivalence Factors for Coherent System using Survival Signature [PDF]

International Journal of Mathematical, Engineering and Management Sciences
This study presents a methodology aimed at enhancing the performance of coherent systems through the application of survival signature analysis, focusing on the calculation of reliability equivalence factors (REFs).
Deepak, Garima Chopra, Deeksha
doaj   +1 more source