Results 71 to 80 of about 60,299 (235)
Journal of Experimental & Clinical Cancer Research, 2009 Background p53AIP1 is a potential mediator of apoptosis depending on p53, which is mutated in many kinds of carcinoma. High survivin expression in non-small cell lung cancer is related with poor prognosis.
Yamamoto Satoshi +6 more
doaj +1 more source
Chromosome Segregation Is Biased by Kinetochore Size [PDF]
, 2018 Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selection ...
Aguiar, P +8 more
core +2 more sources
Survivin – The inconvenient IAP [PDF]
Seminars in Cell & Developmental Biology, 2015 Although technically a member of the Inhibitor of Apoptosis (IAP) gene family, survivin has consistently defied assumptions, refuted predictions and challenged paradigms. Despite its more than 5500 citations currently in Medline, the biology of survivin has remained fascinatingly complex, its exploitation in human disease, most notably cancer ...
openaire +2 more sources
Impact of organic pollutants on phenotype and gene expression in human breast cancer cells
Journal of Applied Toxicology, EarlyView.ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin +7 more
wiley +1 more source
Expression of Survivin and Its Spliced Variants in Bladder Tumors as a Potential Prognostic Marker
Urology Journal, 2009 <p><strong>Introduction: </strong>Survivin, a novel inhibitor of apoptosis, is re-expressed in a vast majority of human cancers and is widely considered as a diagnostic marker of cancers.
Ardalan Ozhand +5 more
doaj
Survivin regulates the expression of VEGF-C in lymphatic metastasis of breast cancer
Diagnostic Pathology, 2012 Background As a known regulator of apoptosis, survivin has positive relationship with lymphatic metastasis in breast cancer. This study aims to detect the difference in expression between survivin and vascular endothelial growth factor-C (VEGF-C) in ...
Cai Xiaopeng +5 more
doaj +1 more source
Journal of Surgical Oncology, EarlyView.ABSTRACT Breast cancer remains a leading cause of cancer‐related mortality among women globally. Vietnamese women experience unique challenges, including sociocultural, linguistic, and systemic barriers, contributing to disparities in screening utilization, late‐stage diagnoses, and treatment outcomes.
Antoinette T. Nguyen +3 more
wiley +1 more source
Chinese Journal of Lung Cancer, 2010 Background and objective Lung cancer is one of the most common cancers worldwide and causes more deaths per year than other cancers. Autoantibody was one hotspot in tumor marker research.
Li MA +5 more
doaj
Survivin expression and its clinical significance in pancreatic cancer
BMC Cancer, 2005 Background Survivin, an inhibitor of apoptosis is expressed in several human cancers. Its expression is known to be associated with poor clinical outcome, but not widely studied in pancreatic cancer.
Lee Kyung Shik +8 more
doaj +1 more source
Journal of International Medical Research, 2020 Objective Recent studies demonstrated that circulating tumor cells (CTCs) contribute to the metastasis of prostate cancer. Survivin knockout could inhibit epithelial-mesenchymal transition (EMT) and suppress several metastatic tumors.
Faying Yang +6 more
doaj +1 more source