Results 51 to 60 of about 2,840,578 (328)

Towards Mass Spectrometry-Based Chemical Exposome: Current Approaches, Challenges, and Future Directions

open access: yesToxics, 2019
The proposal of the “exposome” concept represents a shift of the research paradigm in studying exposure-disease relationships from an isolated and partial way to a systematic and agnostic approach.
Jingchuan Xue   +3 more
doaj   +1 more source

Finite temperature properties of the 2D Kondo lattice model

open access: yes, 1999
Using recently developed Lanczos technique we study finite-temperature properties of the 2D Kondo lattice model at various fillings of the conduction band.
C.C. Yu   +24 more
core   +1 more source

Susceptibility of Monte-Carlo Generated Projected Vortices [PDF]

open access: yes, 2001
We determine the topological susceptibility from center projected vortices and demonstrate that the topological properties of the SU(2) Yang-Mills vacuum can be extracted from the vortex content.
't Hooft   +16 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Enhanced Seroconversion to West Nile Virus Proteins in Mice by West Nile Kunjin Replicon Virus-like Particles Expressing Glycoproteins from Crimean–Congo Hemorrhagic Fever Virus

open access: yesPathogens, 2022
Removal of genes coding for major parts of capsid (C), premembrane (prM), and envelope (E) proteins on the flavivirus genome aborts the production of infectious virus particles where the remaining genome forms a replicon that retains replicability in ...
Pham-Tue-Hung Tran   +6 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

SMARCD1 is an essential expression-restricted metastasis modifier

open access: yesCommunications Biology
Breast cancer is the most frequently diagnosed cancer worldwide, constituting 15% of cases in 2023. The predominant cause of breast cancer-related mortality is metastasis, and a lack of metastasis-targeted therapies perpetuates dismal outcomes for late ...
Christina Ross   +5 more
doaj   +1 more source

Ga NMR study of the local susceptibility in SrCr8Ga4O19: pseudogap and paramagnetic defects

open access: yes, 2000
We present the first Ga(4f) NMR study of the Cr susceptibility in the archetype of Kagome based frustrated antiferromagnets, SrCr$_{8}$Ga$_{4}$O$_{19}$. Our major finding is that the susceptibility of the frustrated lattice goes through a maximum around ...
A. Keren   +28 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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