Results 111 to 120 of about 503,154 (248)
Association of genetic variants in the IRAK-4 gene with susceptibility to severe sepsis [PDF]
, 2012 Jun Yin +5 more
openalex +1 more source
Advanced Biology, EarlyView.This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira +11 more
wiley +1 more source
Exome sequencing identifiesHELBas a novel susceptibility gene for non-mucinous, non-high-grade-serous epithelial ovarian cancer [PDF]
Ed Dicks +20 more
openalex +1 more source
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Advanced Biology, EarlyView.Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
Advanced Engineering Materials, EarlyView.This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
Genes, autoimmunity and pathogenesis of rheumatic heart disease
Annals of Pediatric Cardiology, 2011 Pathogenesis of rheumatic heart disease (RHD) remains incompletely understood. Several genes associated with RHD have been described; most of these are involved with immune responses.
Guilherme L +3 more
doaj
Association of a variable number tandem repeat in the NLRP3 gene in women with susceptibility to RVVC [PDF]
, 2016 Martin Jaeger +12 more
openalex +1 more source
Advanced Functional Materials, EarlyView.The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen +13 more
wiley +1 more source