Results 101 to 110 of about 583,132 (315)
EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot +36 morewiley +1 more sourceReading and language disorders : the importance of both quantity and quality [PDF]
, 2014 Reading and language disorders are common childhood conditions that often co-occur with each other and with other neurodevelopmental impairments. There is strong evidence that disorders, such as dyslexia and Specific Language Impairment (SLI), have a ...Newbury, Dianne F, Paracchini, Silvia, Monaco, AP, Anthony Monaco, Monaco, Anthony P, Paracchini, S, Dianne Newbury, Silvia Paracchini, Newbury, DF +8 morecore +1 more sourceAn xa5 Resistance Gene-Breaking Indian Strain of the Rice Bacterial Blight Pathogen Xanthomonas oryzae pv. oryzae Is Nearly Identical to a Thai Strain
Frontiers in Microbiology, 2020 The rice bacterial blight pathogen Xanthomonas oryzae pv. oryzae (Xoo) constrains production in major rice growing countries of Asia. Xoo injects transcription activator-like effectors (TALEs) that bind to and activate host “susceptibility” (S) genes ...Sara C. D. Carpenter, Prashant Mishra, Chandrika Ghoshal, Prasanta K. Dash, Li Wang, Samriti Midha, Gouri S. Laha, Jagjeet S. Lore, Wichai Kositratana, Nagendra K. Singh, Kuldeep Singh, Prabhu B. Patil, Ricardo Oliva, Sujin Patarapuwadol, Adam J. Bogdanove, Rhitu Rai +15 moredoaj +1 more sourceSomatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen +5 morewiley +1 more sourceA genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium [PDF]
, 2011 Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease.Marsit CJ, Carmen J. Marsit, Oszutowska, Dorota, McLaughlin, John, Hung, Rayjean J, Fish Sherianne, Romkes Marjorie, Key, Timothy, Trichopoulos D, Lacko, Martin, Panico, S, González, C.A., Riboli, E., Oszutowska D, Arzani, Dario, Foglio, Mario, Hayes, Richard B, Schwartz SM, Wilbert H. M. Peters, Hashibe Mia, Tumino R, Dario Arzani, Key Timothy, Szeszenia-Dabrowska, Neonila, Stephen M Schwartz, Vineis P, Zhang Zuo-Feng, McLaughlin J, Lathrop, Mark, Trubicka Joanna, Brennan P., Lorenzo Richiardi, Chabrier, Amelie, Krogh, Vittorio, Chuang, S-C, Boffetta Paolo, Peters, Wilbert HM, Manni, Johannes J, Jingchun Luo, Liloglou T, Heath, S, Shama Buch, Bencko, V, Trichopoulos Dimitrios, Domenico Palli, Khaw KT, Luo, J., Voodern, T., Funkhouser WK, Macfarlane, Tatiana V, Field, John K, Wei Q, Doody David R., McClean Michael D., Herrero, R, Peters, W.H.M., Arzani, D, Macfarlane, TV, Njolstad, I., Quirós JR, Trichopoulou, A., Välk, K., Luo, Jingchun, Zhang, Z.F., Marsit, Carmen J., Martıínez, Carmen, Gaborieau Valerie, Boccia Stefania, H Bas Bueno-de-Mesquita, Hallmans, Göran, Alexandru Bucur, Conway, D. I., Blanché, H., Amelie Chabrier, Menezes, Ana, Lagiou, Pagona, Castellsagué, X, Tumino, R., Menezes Ana, José Eluf Neto, Neto JE, Koifman Sergio, Lagiou, P., McKay JD, Peters, W.H., Luo, JC, Riboli, Elio, Garrote LF, Tumino, Rosario, Fabianova, Eleonora, Conway, David I., Chen C, Luo Jingchun, Manni, Johannes J., Wünsch Filho V, Sturgis EM, Andres Metspalu, Heather H. Nelson, Ardanaz, Eva, Kumle, Merethe, Gary J. Macfarlane, et al., Gut, Ivo G., Therese Truong, -, Philip Lazarus, Navarro Carmen, Chabrier, A, Ivo G. Gut, Vatten, Lars Johan, Liloglou, T, John K Field, Benhamou Simone, Chabrier A, Bueno de Mesquita, H. Bas, Krogh V, Hashibe, M., Chabrier, A., Szeszenia-Dabrowska Neonila, Marsit, CJ, Overvad, Kim, Johannes J. Manni, Peters, W. H. M., Hung, Rayjean J., Funkhouser William K., Doody, DR., Clavel-Chapelon, F., Palli, D., Navarro, Carmen, Gallagher Carla J., Marsit Carmen J., Muscat, JE, Trubicka J, Eleonora Fabianova, John K. Field, Bueno-de-Mesquita, HB, Antonia Trichopoulou, Njølstad, I, Ahrens Wolfgang, Neto, J.E., Pagona Lagiou, Wei Qingyi, Gary E. Goodman, Shen-Chih Chang, Heath, S., Voodern, Tõnu, Herrero Rolando, Clavel Chapelon F, Peeters, Petra H M, Talamini, R, McClean MD, McLaughlin John, Kelsey, Karl T., Heath Simon, Galan, P., Vineis, P., Goodman, G.E., Chuang, S.-C., Kumle, M., Bucur Alexandru, Peeters, Petra H. M., Carmen Navarro, H. Bas Bueno-de-Mesquita, Ardanaz, E, Quirós, José Ramón, Peters, Wilbert H. M, Galan P, Hung, RJ, Gary E Goodman, Wünsch-Filho, V, Zhang, ZF, Muscat JE, Holcatova, Ivana, Tjønneland, Anne, Gallagher, Carla J., Francoise Clavel-Chapelon, Chang, SC, Byrnes G, Navarro, C., Galan Pilar, Doody, D.R., Goodman, Gary E, Gaborieau, V, Nukui, Tomoko, Lathrop Mark, Fabianova E, Olshan, Andrew F, Marjorie Romkes, David R. Doody, Tõnu Voodern, González, CA, Trichopoulou A, Bouchardy, C., Schwartz, Stephen M, Toner, ME, Wuensch-Filho, V, Gut IG, Dimitrios Trichopoulos, Kjaerheim, K., Bucur, A, Vooder T, Castellsagué X, Trichopoulos, D., Peeters, P.H., Simonato, Lorenzo, Nelson, HH, Olshan AF, Therese Truong,, Delepine, Marc, Wolfgang Ahrens, Chang, S-C, Franceschi, S., Brennan, P, Bocciai, Stefania, Curado, M. P., Hayes, Richard B., Joshua E Muscat, Peters WH, Ramon Quiros, J., Zhong Shilong, Hayes, RB, Schwartz, Stephen M., Schwartz, SM, Gallagher CJ, Heather H Nelson, Garrote, L.F., Macfarlane, Tatiana V., Quirós J. Ramón, Galan, P, William K. Funkhouser, Weissler, MC, Carlos A. González, Cadoni, G, Anne Boland, Chang SC, Palli, Domenico, Therese Truong, Curado MP, McClean, MD, McKay James D., Macfarlane TV, Välk Kristjan, Marsit, C.J., Antonio Agudo, Overvad, K., Wünsch-Filho, Victor, Talamini R, Linseisen, Jakob, Zaridze David, Lenka Foretova, Bueno-de-Mesquita, H.B., Peeters, P. H. M., Neto, José Eluf, Wünsch-Filho, V., Larrañaga N, Sturgis, E.M., Patricia A. McKinney, Carmen Martínez, Kelsey, KT, Michael D. McClean, Lubiński, J., Delepine, M, Bueno-de-Mesquita H. Bas, Karl T. Kelsey, Overvad K, Oszutowska, D, Claire M Healy, MacFarlane, Tatiana, Ariana Znaor, Neonila Szeszenia-Dabrowska, Castellsagué, Xavier, Tatiana V Macfarlane, Zhang ZF, Wei, Q, Khaw, KT, Quirós, J.R., Funkhouser, WK, Truong, T., Chuang, S. -C., Bueno de Mesquita HB, Simonato, L, Curado, Maria Paula, Weissler Mark C., Chuang, Shu-Chun, Lathrop, M, Doris Lechner, Valk, K, Heath, Simon C., Marsit, Carmen J, Romkes M, Linseisen Jakob, Martínez C, Hung, R.J., Gut, I.G., Wang LE, Lazarus P, Zelenika, D, Romkes, Marjorie, Trichopoulou, Antonia, Agudo Antonio, Linseisen, J., Musca, Joshua E., Hayes RB, Chang, S.C., Jakob Linseisen, William K Funkhouser, Chen Chu, Brennan, P., Field, John K., Palli D, Gallagher, C. J., Macfarlane, GJ, Vatten L, Erich M Sturgis, Larrañaga Nerea, Kristina Kjaerheim, Carla J Gallagher, Shangina, O., Manni, JJ, Conway, D.I., Stefania Boccia, Zhong, S., Navarro C, Quirós, J. R., Krogh, V, Bouchardy C, Overvad, K, Key T, Simonato Lorenzo, Lechner D, Chabrier Amelie, Oxana Shangina, McClean, Michael D., Foglio, M., Boffetta, Paolo, Luo J, Zhong, SL, Sturgis, EM, Larrañaga, N., Fernandez Garrote, L, Key, T, Weissler, Mark C., Key, T., Zhong, Shilong, Lechner, D., Hallmans Göran, Kelsey, K. T., Palli, D, Agudo, Antonio, Healy Claire M., Khaw, Kay-Tee, Linseisen J, McKay, JD, Bueno-de-Mesquita, H Bas, Janout, V, Voodern Tõnu, Bouchardy Christine, Doody, David R., Christine Bouchardy, Weissler, M. C., Macfarlane, Gary J., Olshan, A.F., Lorenzo Simonato, Manni, J. J., Richard B. Hayes, Vatten, L, Vladimir Bencko, Vatten, L., Horwitz, Marshall S., Shangina Oxana, Doody, DR, Kristjan Välk, Fish, S, Joshua E. Muscat, Bueno-de-Mesquita, Bas, Ardanaz, E., Kumle M, Kumle Merethe, Bencko, V., Zelenika, Diana, Chang Shen-Chih, Peeters, Petra HM, Castellsagué, X., Clavel-Chapelon Francoise, Manni Johannes J., Clavel-Chapelon, Francoise, Koifman S, Tjønneland, A., Eva Ardanaz, Wang, Li-E., Rudnai, Peter, Nerea Larrañaga, Fernandez Garrote, Leticia, Overvad Kim, Goodman, G. E., Simonato L, Blanche´, Hélène, Zhang, Z. -F., INHANCE Consortium, Ahrens, Wolfgang, Cadoni, Gabriella, Göran Hallmans, Talamini Renato, McLaughin, John, Szeszenia-Dabrowska, N., Curado, M.P., Menezes, A, Carlos A González, Holcatova, I., Merethe Kumle, Schwartz, S.M., Znaor, Ariana, Olshan, Andrew F., Lubiński, J, David I. Conway, Martínez, C, McLaughlin, John R., Macfarlane, G.J., Hayes, R. B., Benhamou S, Doody DR, Hallmans G, Truong Therese, Cadoni Gabriella, Neto, J. E., Lener, M., Boffetta, P., Field, J.K., Hayes, R.B., Merletti, F, Krogh Vittorio, Canova, Cristina, McKay, James D., Salvatore Panico, Healy, C. M., McKinney, PA, Weissler, Mark C, Zaridze, D., Byrnes, G, Conway, David I, Szeszenia Dabrowska N, Larrañaga, N, Brennan Paul, Foretova L, Ramon Quiros, J, McKinney, P.A., Sturgis, E. M., Tatiana V. Macfarlane, Muscat, Joshua E., Chuang Shu-Chun, Luo, J, J. Ramón Quirós, ELUF NETO, Jose, McKinney PA, Lacko Martin, Richard B Hayes, Canova, C., Zaridze, David, James D McKay, Rayjean J. Hung, Macfarlane, T. V., Boeing, H., Rudnai, P., Claire M. Healy, Paolo Vineis, Trubicka, J, Kjaerheim Kristina, Zhang, Zuo-Feng, Weissler, M.C., Trubicka, Joanna, Välk, Kristjan, Victor Wünsch-Filho, Foretova, L., Wang, L-E, McLaughlin, J., Lagiou, P, Martínez, C., Peters, Wilbert H. M., Wei, QY, Znaor Ariana, Gaborieau, V., Graham Byrnes, Benhamou, Simone, Heath S, Boccia S, Wang, Li-E, David Zaridze, Cadoni G, Hallmans, G, Janout V, Barzan L, Macfarlane, G. J., Njølstad, Inger, Timothy Key, McClean, M.D., Silvia Franceschi, Boland A, David I Conway, Lars Vatten, Peter Rudnai, Nelson HH, Wei, Q., Qingyi Wei, Zaridze, D, Znaor A, McClean, M. D., Clavel-Chapelon, F, J Ramón Quirós, Nukui, T, Franceschi, S, McKinney Patricia A., Blanche, H, Tõnu Vooder, Garrote, L. F., Panico Salvatore, Bucur, A., Trubicka, J., Boland, A., Shangina O, Nelson, Heather H., Garrote, LF, Menezes, Ana A., Muscat, Joshua E, Li-E Wang, Vineis, Paolo, Sherianne Fish, Mark C. Weissler, Valerie Gaborieau, Zhong, S, Vaelk, Kristjan, Bueno-de-Mesquita, H. B., Peters Wilbert H. M., Riboli, E, Mary E Toner, Wang, LE, Gut Ivo G., Chuang, SC, Macfarlane Tatiana V., Andrew F. Olshan, Muscat Joshua E., Goodman, GE, Chuang SC, Toner, Mary E., González, C. A., Välk K, Gonzalez, Carlos A., Mark Lathrop, Nukui T, Jan Lubiński, Macfarlane, TV., Franceschi, Silvia, Boffetta, P, Lazarus, P., Hélène Blanché, Toner, Mary E, Metspalu Andres, Zelenika Diana, Vatten Lars, Peeters Petra H. M., Toner Mary E., Funkhouser, William K, Lechner, D, Barzan Luigi, James D. McKay, Curado Maria Paula, Mario Foglio, Blanché, Hélène, McKinney, Patricia A., Ahrens, W, Petra H M Peeters, Romkes, M, Lathrop M, Wei, Qingyi, Conway David I., Goodman, Gary E., Chen, Chu, Fish, Sherianne, Hashibe, M, Key, Timothy J., Heiner Boeing, Njølstad Inger, Kelsey, K.T., Richiardi Lorenzo, Rudnai, P, Nelson Heather H., Delepine Marc, Fish, S., Foglio M, Shangina, O, Quirós, JR, Zuo-Feng Zhang, Healy, C.M., Simon Heath, Byrnes, Graham, McKinney, Patricia A, Hashibe M, Khaw Kay-Tee, Elio Riboli, Carla J. Gallagher, Boeing, H, Franceschi S, Lazarus, Philip, Manni, J.J., Njolstad, Inger, Liloglou, T., Bucur A, Kelsey, Karl T, Lissowska, J, Lowry R, Arzani, D., Koifman, Sergio, Trichopoulou, A, Benhamou, S, Fabianova, E., Buch S, Vooder, T., Arzani Dario, Lacko M, Boland Anne, Martin Lacko, Menezes, Ana M., Oszutowska, D., Andrew F Olshan, Peeters PH, Ahrens W, Castellsagué Xavier, Macfarlane GJ, Merletti F, Healy, Claire M, Byrnes Graham, Lissowska Jolanta, Boland, Anne, Healy, Claire M., Lagiou P, McKinney, P. A., Doody, D. R., Kim Overvad, Menezes, A., Martínez Carmen, Gallagher, C.J., Herrero, R., Carmen J Marsit, Barzan, L., Wang, L. -E., Barzan, L, Toner, M. E., Kjaerheim, K, Wünsch-Filho Victor, Gallagher, Carla J, Vooder, Tõnu, Boccia, S., González CA, Rolando Herrero, González Carlos A., Fabianova Eleonora, Paul Brennan, Foretova, L, Bencko V, McKay, J.D., Vineis Paolo, Trichopoulos, Dimitrios, Boccia, Stefania, Liloglou, Triantafillos; id_orcid, Chen, C, Quirós, J Ramón, Lacko, M, Fish S, Macfarlane, G, Lowry Ray, Sturgis, Erich M, Holcatova Ivana, Doody, David R, Riboli Elio, Brennan, Paul, Peeters, PHM, Tjonneland, A, Voodern, T, Tumino, R, Vineis, P, Liloglou Triantafillos, Trichopoulou Antonia, Macfarlane, T.V., Heath, Simon, Toner, M.E., Weissler MC, Ahrens, W., Hayes Richard B., Peeters, P.H.M., Tjønneland Anne, Hayes, RB., Tumino Rosario, Paolo Boffetta, Foretova Lenka, Merletti Franco, Koifman, S., Marc Delepine, Lubiński Jan, Njolstad, I, Franco Merletti, Stephen M. Schwartz, Menezes A, Muscat, J.E., Funkhouser, William K., Bencko Vladimir, Conway, DI, Trichopoulos, D, Bueno-de-Mesquita, H. Bas, Richiardi, L, Gallagher, CJ, Field, J. K., Lacko, M., Vittorio Krogh, Buch Shama, Fabianova, E, Zaridze D, Arzani D, Agudo, A., Rudnai P, Lazarus, P, Panico, Salvatore, Field JK, Kjaerheim, Kristina, Gut, IG, Erich M. Sturgis, Merletti, F., Karl T Kelsey, David R Doody, Mia Hashibe, Boeing Heiner, Larrañaga, Nerea, Zhang, Z-F, Lubiński, Jan, McKay, James D, Funkhouser, W.K., Hung RJ, Rudnai Peter, Janout, V., Canova, C, Linseisen, J, Kelsey Karl T., Macfarlane, Gary J, Peters, Wilbert H.M., Lissowska, J., Chen, C., Schwartz Stephen M., Lubiński J, Muscat, J. E., Martínez, Carmen, Buch, Shama, Curado, MP, Njølstad I, Funkhouser, W. K., Kjærheim, Kristina, Truong, Therese, Blanché Hélène, Bucur, Alexandru, Canova C, Chu Chen, Peters, Wilbert H. M., Lener, Marcin, Kay-Tee Khaw, Krogh, V., Khaw, K-T, Herrero, Rolando, Hung Rayjean J., Delepine M, Xavier Castellsagué, Petra H. M. Peeters, Joanna Trubicka, Peters, WHM, Holcatova I, Delepine, M., González, Carlos A, Talamini, R., Healy, CM, Richiardi, Lorenzo, Quirós, J. Ramón, Panico, S., Macfarlane Gary J., Kjaerheim K, Simone Benhamou, Jolanta Lissowska, Healy CM, Byrnes, G., Goodman GE, Peters, Wilbert H M, Foglio Mario, Oszutowska Dorota, Kumle, M, Lowry, R., Gabriella Cadoni, Benhamou, S., Zhong S, Field John K., Cadoni, G., Richiardi, L., John McLaughlin, Chang, Shen-Chih, Buch, S., Boeing H, Lener Marcin, Metspalu, A., Blanché H, Conway, DI., Neto, JE, McLaughlin, J, Maria Paula Curado, Lowry, Ray, Hallmans, G., Wuensch-Filho, Victor, Neto José Eluf, Buch, S, Merletti, Franco, Metspalu A, Metspalu, A, Ray Lowry, Ardanaz E, Znaor, A, Garrote Leticia Fernández, Lechner, Doris, Sergio Koifman, Lissowska J, Boeing, Heiner, Herrero R, Tjonneland, Anne, Shu-Chun Chuang, Marcin Lener, Macfarlane, GJ., McKay, J. D., Romkes, M., Therese, T, Gary J Macfarlane, Gut, I. G., Liloglou, Triantafillos, Mary E. Toner, Rayjean J Hung, Conway DI, Vatten, Lars, Manni JJ, Khaw, K.T., Palli Domenico, Dorota Oszutowska, Shangina, Oxana, Lowry, R, Olshan, AF, Truong T, Lathrop, M., Vladimir Janout, Chuang, S.C., Nukui, T., Field, JK, Luigi Barzan, Rosario Tumino, Gaborieau V, Ivo G Gut, McClean, Michael D, Lechner Doris, Goodman Gary E., Szeszenia-Dabrowska, N, Riboli E, Hallmans, Göran,, Boland, A, Znaor, A., Njølstad, I., Nelson, H.H., Franceschi Silvia, Schwartz, S. M., Zelenika, D., Olshan Andrew F., Janout Vladimir, Zelenika D, Inger Njølstad, Olshan, A. F., Shilong Zhong, Khaw, K. -T., Koifman, S, Renato Talamini, Anne Tjønneland, Agudo, A, Kelsey KT, Wang, L.E., Agudo A, Lazarus Philip, Lagiou Pagona, Lener, M, Nelson, Heather H, Cristina Canova, Chang, S. -C., Janout, Vladimir, Gut, Ivo G, Horwitz, M.S., Johannes J Manni, Gaborieau, Valerie, Bouchardy, Christine, Nukui Tomoko, Leticia Fernández Garrote, Bouchardy, C, Navarro, C, Simonato, L., Ivana Holcatova, Triantafillos Liloglou, Toner ME, Boffetta P, Tjønneland A, Talamini, Renato, Mark C Weissler, Holcatova, I, Tomoko Nukui, Barzan, Luigi, Bencko, Vladimir, Hashibe, Mia, Michael D McClean, Truong, T, Lissowska, Jolanta, Canova Cristina, Wang Li-E, Pilar Galan, Marsit, C. J., Vaelk, K, Patricia A McKinney, Garrote, Leticia Fernández, Wilbert H M Peters, Ardanaz Eva, Foglio, M, Ana Menezes, Hung, R. J., Sturgis Erich M., Galan, Pilar, Diana Zelenika, Nelson, H. H., Boccia, S, Foretova, Lenka, Richiardi L, Sturgis, Erich M., Metspalu, Andres, Lener M +934 morecore +1 more sourceHijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...Gabriela Marinescu, Yi Fengwiley +1 more sourceLongitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay +15 morewiley +1 more sourceInterpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo +7 morewiley +1 more sourceSnTox3 acts in effector triggered susceptibility to induce disease on wheat carrying the Snn3 gene [PDF]
, 2009 The necrotrophic fungus Stagonospora nodorum produces multiple proteinaceous host-selective toxins (HSTs) which act in effector triggered susceptibility.McDonald, B., McDonald Megan C., Nunez, A., Faris Justin D., Liu, Z., Zhaohui Liu, Friesen Timothy L., Tan, Kar-Chun, Oliver, R.P., Faris, Justin D., Kar-Chun Tan, Oliver, Richard P., Rasmussen, Jack B., Lu Shunwen, Solomon Peter S., Richard P Oliver, Friesen, T., Tan, K.C., Megan C McDonald, McDonald, M., Oliver Richard P., Bruce A McDonald, Friesen, T.L., Jack B Rasmussen, McDonald, Megan C., McDonald, Megan C.; id_orcid, Faris, J.D., Peter S Solomon, Liu Zhaohui, Nunez, Alberto, McDonald, Bruce A., Rasmussen, J., Rasmussen Jack B., Friesen, Timothy L., Faris, J., McDonald Bruce A., Oliver, Richard, Liu, Zhaohui, McDonald, B.A., Rasmussen, J.B., Nunez Alberto, Solomon, Peter S., Tan Kar-Chun, Timothy L Friesen, Solomon, P., McDonald, M.C., Lu, S., Shunwen Lu, Justin D Faris, Alberto Nunez, Lu, Shunwen, Solomon, P.S. +51 morecore +2 more sources
