Results 111 to 120 of about 583,132 (315)

Transcriptional profiling of Impatiens walleriana genes through different stages of downy mildew infection reveals novel genes involved in disease susceptibility

open access: yesOrnamental Plant Research
Impatiens downy mildew is a highly destructive disease of Impatiens walleriana, an economically important bedding ornamental crop. This disease is caused by a recently emerged pathogen Plasmopara obducens.
Stephanie Suarez   +2 more
doaj   +1 more source

Search for schizophrenia susceptibility genes

open access: yesBiological Psychiatry, 2000
Identification of a gene or genes that contribute to the development of schizophrenia, a complex psychiatric disorder, may be possible through genetic linkage analysis. Although to date no single causative gene has been identified, several chromosomal loci have shown positive linkage results and are under investigation as tentative schizophrenia ...
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Editorial: Genetic features contributing to eye development and disease

open access: yesFrontiers in Cell and Developmental Biology, 2022
Wenchang Xu   +4 more
doaj   +1 more source

Disease susceptibility genes for autism

open access: yesAnnals of Medicine, 2003
Autism is a complex neurodevelopmental disorder characterized by impairment in social interaction accompanied by a delay or lack of language, restricted interests, stereotyped behavior, and repetitive movement. Genetic predisposition to autism is evident from family and twin studies, and heritability in idiopathic autism is estimated at over 90 ...
Irina N, Bespalova, Joseph D, Buxbaum
openaire   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Genética de la esquizofrenia: avances en el estudio de genes candidatos

open access: yesRevista de Biología Tropical, 2004
La esquizofrenia es una de las enfermedades mentales severas que afecta a un 1% de la población mundial. Es claro que en su etiología participan factores genéticos y ambientales.
Adriana Pacheco, Henriette Raventós
doaj  

Psicofarmacogenética: uma nova abordagem terapêutica

open access: yesBrazilian Journal of Psychiatry, 1999
A psicofarmacogenética é uma nova área de investigação derivada da psicofarmacologia e da genética. Esta disciplina procura identificar genes de suscetibilidade associados a diferentes padrões de resposta terapêutica e/ou ao variado grau de efeitos ...
Homero Pinto Vallada Filho
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The genome and lifestage-specific transcriptomes of a plant-parasitic nematode and its host reveal susceptibility genes involved in trans-kingdom synthesis of vitamin B5 [PDF]

open access: yes, 2021
Plant-parasitic nematodes are a major, and in some cases a dominant, threat to crop production in all agricultural systems. The relative scarcity of classical resistance genes highlights a pressing need to identify new ways to develop nematode-resistant ...
Siddique, Shahid   +4 more
core   +1 more source

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