Results 121 to 130 of about 9,010,468 (307)

Silencing of six susceptibility genes results in potato late blight resistance

Transgenic research, 2016
Phytophthora infestans, the causal agent of late blight, is a major threat to commercial potato production worldwide. Significant costs are required for crop protection to secure yield.
Kaile Sun, A. Wolters, J. Vossen, Maarten E. Rouwet, A. Loonen, E. Jacobsen, R. Visser, Yu-Ling Bai   +7 more
semanticscholar   +1 more source

Genome wide high density SNP-based linkage analysis of childhood absence epilepsy identifies a susceptibility locus on chromosome 3p23-p14 [PDF]

, 2009
Childhood absence epilepsy (CAE) is an idiopathic generalised epilepsy (IGE) characterised by typical absence seizures manifested by transitory loss of awareness with 2.5–4 Hz spike-wave complexes on ictal EEG.
Sander, Thomas, Eeg-Olofsson, O, Everett, KV, Everett, Kate V., Friis, Mogens Laue, Dulac, Olivier, Siren, Auli, Dooley, Joseph M, Aschauer, H, Kjeldsen, MJ, Dulac, O, Wirrell, Elaine, Covanis, Athanasios, Brouwer, Oebele, Covanis, A, Sirén, A, Aicardi, Jean, Gardiner, RM, Durner, Martina, Robinson, R, Nabbout, Rima, Gardiner, R. Mark, McKeigue, Paul, Sander, T, Dooley, JM, Gardiner, R Mark, McKeigue, Paul; id_orcid, Chioza, BA, Aschauer, Harald, Everett, Kate V, Eeg-Olofsson, Orvar, Brouwer, O, Nabbout, R, McKeigue, P, Robinson, Robert, Chioza, Barry A., Dooley, Joseph M., Nashef, L, Feucht, Martha, Feucht, M, Guerrini, R, Aicardi, J, Durner, M, Nashef, Lina, Wirrell, E, Callenbach, P, Guerrini, Renzo, Callenbach, Petra, Chioza, Barry A, Friis, ML, Kjeldsen, Marianne Juel, Eeg-Olofsson, Orvar,   +51 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Categories of pathways associated with PE susceptibility genes.

, 2015
Categories of pathways associated with PE susceptibility genes.
Hannah E. J. Yong (744942), Katy A. Freed (744943), Rosemary J. Keogh (744944), Padma Murthi (158212), Phillip E. Melton (104184), Matthew P. Johnson (104195), Shaun P. Brennecke (178499), Eric K. Moses (104201), Bill Kalionis (666344)   +8 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Editorial: Genetic features contributing to eye development and disease

Frontiers in Cell and Developmental Biology, 2022
Wenchang Xu, Xinqi Liu, Xinqi Liu, Wenjuan Han, Ling Zhao   +4 more
doaj   +1 more source

Transcriptional profiling of Impatiens walleriana genes through different stages of downy mildew infection reveals novel genes involved in disease susceptibility

Ornamental Plant Research
Impatiens downy mildew is a highly destructive disease of Impatiens walleriana, an economically important bedding ornamental crop. This disease is caused by a recently emerged pathogen Plasmopara obducens.
Stephanie Suarez, Zunaira Afzal Naveed, Gul Shad Ali   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Genética de la esquizofrenia: avances en el estudio de genes candidatos

Revista de Biología Tropical, 2004
La esquizofrenia es una de las enfermedades mentales severas que afecta a un 1% de la población mundial. Es claro que en su etiología participan factores genéticos y ambientales.
Adriana Pacheco, Henriette Raventós
doaj  

Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families

Journal of Medical Genetics, 2015
Introduction Gene panel testing for breast cancer susceptibility has become relatively cheap and accessible. However, the breast cancer risks associated with mutations in many genes included in these panels are unknown.
Jun Li, Huong D. Meeks, Bing Feng, S. Healey, H. Thorne, I. Makunin, J. Ellis, I. Campbell, M. Southey, G. Mitchell, D. Clouston, J. Kirk, D. Goldgar, G. Chenevix-Trench   +13 more
semanticscholar   +1 more source