Results 81 to 90 of about 9,010,468 (307)
A genome-wide association search for type 2 diabetes genes in African Americans [PDF]
, 2011 African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity.Bostrom, Meredith A, Ingelsson, E., Shields, B.M., Fischer-Rosinsky, A., Sanna, Serena, Roh, BH, Boerwinkle, E., Anneli Pouta, Qi, L., Hicks, Andrew A, Fedson, A.C., Palmer, L.J., Laura J McCulloch, Fedson, AC, Cao, A, Lajunen, T., Glazer, NL, Toshiko Tanaka, Peter Shrader, Kao, Wen H L, Tiinamaija Tuomi, Couper, DJ, Christine Cavalcanti-Proença, Steven A McCarroll, Kaprio, Jaakko, Navarro, Pau, Hammond, Naomi, Roh, B., Antti Jula, Qi, Lu, Soumya Raychaudhuri, Palmer, CN, Uitterlinden, André G, Perry, J.R., Thomas A Buchanan, Syvänen, A.C., Barroso, Inês, Divers Jasmin, Boehm, Bernhard O, Qi Sun, Stefansson, K, Johnson, Paul RV, Benediktsson, R., Dedoussis, GV, de Geus, E.J., Ardlie, Kristin, Nigel W Rayner, Kong, A., Eric Brunner, Qi, L, Michael A Province, de Geus, Eco J C, Denis Rybin, Smith, GD, Hallmans, Göran, Rivadeneira, F, Meigs, JB, Meredith A Bostrom, Ganser, M, Raychaudhuri, Soumya, Antonio Cao, Visvikis-Siest, S., Zethelius, Björn, Johnson, T, Alisa K Manning, Steve A McCarroll, Jula A, Patrik K E Magnusson, Penninx, B.W.J.H., Syddall, H, Jarvelin MR, Freedman, BI, Platou, Carl Geoffrey Parrinder, Jessica M. Hester (190247), Pattou, F., Peter S Chines, et al., Lajunen, Taina, Peter Henneman, Sladek, R, Nicholette D. Palmer (190239), Doney, A., Vitart, Veronique, Herder, C, Hercberg, S., James S Pankow, Morris, AD, Doney, AS, Katherine S Elliott, Morris, AP, Wright, A.F., Magnusson, Patrik KE, Jaakko Tuomilehto, Robertson, N.R., Dupuis, Josée, Pfeiffer, Andreas F H, Graessler, J, Wareham, N.J., Holly Syddall, Li, Y., Ulf Gyllensten, Joshua P Lewis, Silveira, Angela, Heath, SC, Franzosi, MG, Pfeiffer, A.F., Valeriya Lyssenko, Seedorf, U, Böttcher, Yvonne, Josée Dupuis, Stavroula Kanoni, Doney, Alex SF, Illig, T., Galan, P., Pedersen, Nancy L, Gabe Crawford, Bowden Donald W., Brunner, Eric, Andrew P Morris, Jackson, A.U., Laila Simpson, Marre, M, Knight, Beatrice, Wilson, James F, Dupuis, J, Pamela J Hicks, Jennie Hui, Ian N M Day, Yun Li, van Dam, Rob M, Jaqueline C M Witteman, Bornstein, SR, Bostrom, Meredith A., Lu Lingyi, Ripatti, S., Hung, J, Ng Maggie C. Y., Waterworth, DM, Ruokonen, Aimo, Wright, AF, Hottenga, J.J., Aulchenko, Y.S., Wu, G, Palmer, LJ, Hercberg, Serge, Pakyz, R, Hicks, A.A., Sijbrands, EJ, Boehm, B.O., Blagieva, R., Waterworth, Dawn M, Thorsteinsdottir, U, Polasek, Ozren, M Carola Zillikens, Ruth J F Loos, Shriner, D, Jarvelin, MR, Cooke, J., Brenda W J H Penninx, Aroon D Hingorani, Elliott, KS, Sijbrands, E., Guanming Wu, Borch-Johnsen, Knut, Hillman, D.R., Sale Michele M., Jackson, Anne U, Brunner, E, Cooke, JN, Paul R V Johnson, Ferreira, T., Yarnell, JW, Amy Swift, Tuomilehto J, Collins, FS, George V Dedoussis, Ruokonen, A, Zhao, JH, Egan, J.M., Timon W van Haeften, Kivimaki, M., Knut Borch-Johnsen, Pramstaller, PP, Langefeld, Carl D., Tuomi, T., Cooke, Jessica N, Vollenweider, P, Elliott, P., Peter Paul Pramstaller, Owen, KR, Wheeler, Eleanor, Rolandsson, Olov,, Silander K, Suzannah J Bumpstead, Roh, Bong H, Aimo Ruokonen, Tanaka, T, Griffin, Simon, Marjo-Riitta Jarvelin, Spector, Timothy D, Richard N Bergman, van Haeften, TW, Dawn M Waterworth, Ganser, M., Mägi, R., Beilby, John P, Smith, N.L., Walters, G Bragi, Tichet, Jean, Tuomilehto, J., Swift, Amy J, Galan, P, Jørgensen, T., Serge Hercberg, Kenneth Rice, Deloukas, P, María Teresa Martínez-Larrad, An, P, Hansen, T., Serena Sanna, Pearson, D., Paolisso, G, Andreas F H Pfeiffer, Josephine M Egan, Sijbrands, E, Robertson, Neil R, Mohlke, K.L., Beatrice Knight, Sethupathy, P, Campbell, Harry, Bennett, A.J., Rhian Gwilliam, Song, K, Rolandsson, O, Voight, Benjamin F, Heath, S.C., Dorret I Boomsma, Leena Peltonen, Magnusson, Patrik K E, Bochud, M., Bergmann, S, Gloyn, A.L., Grallert, H., Shriner Daniel, Kari Stefansson, Zeggini, E, Hadjadj, S, Charles N Rotimi, Steinthorsdottir, V., Hartikainen, AL, Florez, Jose C, Wagner, Peter J, Rafn Benediktsson, Ripatti, S, Lindgren, Cecilia M, Danielle Posthuma, Bong H Roh, Adeyemo, A, Mark O Goodarzi, Smith, G.D., François Pattou, Palmer, N., Timothy M Frayling, Wing, Maria R, Fox, C.S., Oliver M Hofmann, Freedman Barry I., Guangju Zhai, Palmer, Colin N A, Torben Hansen, Zelenika, D, Li, M., Thorand, B, Langefeld, C.D., Franklin, Christopher S, Watanabe, RM, Manning, Alisa K, Yavuz Ariyurek, Walley, A, Wilson, J.F., Pedersen, NL, Pedersen, O., Posthuma, D., Beilby, JP, Palmer, ND, Gwilliam, R, Soranzo, N., Brunner, E., Seedorf, U., Waeber, G., Winston A Hide, Pouta, A., Perry, JR, Ferrara, A, Wichmann, HE, Boström, Kristina Bengtsson, Segrè, A.V., Pichler, Irene, Silander, Kaisa, Wilson, James F; id_orcid, Peter J Wagner, Kovacs, P, Le Bacquer, O, Kaprio, J, Egan, Josephine M, Bergmann, S., Marco Orrù, Johnson, Paul R V, Candace Guiducci, Frayling, Timothy M, Ng, Maggie C. Y., Posthuma, D.; id_orcid, Illig, T, Jerome I Rotter, McDonough, Catrin W, Cristen J Willer, Willemsen, G.; id_orcid, Prokopenko, I, Payne, Felicity, Ganser, Martha, Navarro, P., Day, I.N., Kristian Hveem, Hattersley, Andrew T, Florez, JC, Kaisa Silander, Kovacs, Peter, Reedik Mägi, Michael N Weedon, Grarup, N., Hayward, Caroline, Schwarz, Peter, van Vliet-Ostaptchouk, Jana V, Albert Hofman, Kaakinen, M., Amanda J Bennett, Voight, B.F., Lingyi Lu, Rotimi, C.N., Olov Rolandsson, Göran Hallmans, Hottenga, Jouke Jan, Hicks, AA, Megan E Rudock, Kuusisto, Johanna, An, Ping, Adeyemo, A., McDonough CW, Weedon, MN, Barter, Philip, Oostra, B.A., Rayner, NW, Elliott, Amanda, Watkins, Hugh, Christian Gieger, Buchanan, Thomas A, Daniel Shriner (137188), Amanda L Elliott, Christine Proença, Divers, J, Morken, Mario A, Lathrop, G.M., Samy Hadjadj, Kristin Ardlie, Song, Kijoung, Michael Boehnke, Spector, T.D., Sijbrands, E.J., Elliott, Amanda L, Taina Lajunen, Scott, LJ, Hicks, P.J., Jessica N Cooke, McDonough, C., Wilson, JF, Forouhi, NG, Dina, Christian, Bumpstead, S.J., Waeber, G, Shields, B., Aulchenko, Yurii S, Perry, John RB, Jose C Florez, Province, Michael A, Peter Nilsson, Carl D Langefeld, Raychaudhuri, S, Carl Platou, Williams, G.H., Robert Sladek, Crisponi, L., Gloyn, AL, Petersen, Ann-Kristin, McDonough, CW, Shields, BM, Paolisso, Giuseppe, Zillikens, MC, Leif Groop, Hadjadj, Samy, Couper, D.J., Goncalo R Abecasis, Bumpstead, S, McPherson, R., Erdos, Michael R, Braxton D Mitchell, Froguel, P., Peter Kovacs, Timpson, N.J., Matthew J Neville, Froguel, P, Fox, Caroline S, Sutapa Mukherjee, Rocheleau, Ghislain, Johnson, PR, Uda, M., Pedersen, Oluf, Mark Walker, Wheeler, E., Groop, L, Boehnke, M, Sanna, S, Isomaa, B., Hillman, DR, Wing, Maria, Hitman, G.A., Assiamira Ferrara, Peltonen, L, Kaakinen M, Owen, Katharine R, Hu, F.B., Sharp, SJ, Cooper, Matthew N, Langenberg, C, Owen, K.R., Strassburger, Klaus, Tuomi T, McCulloch, Laura J, Bostrom, Meredith, Swift, A.J., Simon C Potter, Joshua P. Lewis (190257), Cao, A., Waeber, Gérard, Sijbrands, Eric, Bochud, Murielle, Jana V van Vliet-Ostaptchouk, Lind, Lars, Palmer, Colin NA, Ebrahim, S., Hveem, K., Navarro, P, Le Bacquer, Olivier, van Dijk, KW, Kong, Augustine, Kesaniemi YA, Wagner, P.J., Mooser, Vincent, Uitterlinden, AG, Sovio, U, Joshua Randall, Gieger, C, Pakyz, Ruth, Mandy van Hoek, van Vliet-Ostaptchouk, JV, Gérard Waeber, Wichmann, H-Erich, Marmot, M, Welch, R.P., Matthew E. Talbert (190255), Goel, Anuj, Watkins, H., Pfeiffer, Andreas FH, Timothy D Spector, Schlessinger, D., Isomaa, B, Narisu, N., Seppo Koskinen, Ziegler Julie T., Chines, P.S., van Duijn, CM, Graessler, J., Pramstaller, Peter Paul, Sparsø, T, MAGIC Consortium,, Langefeld, CD, Campbell, Harry; id_orcid, Jarvelin, M.R., Blagieva, Roza, Scott Grundy, Singleton, Andrew, Johnson, T., Salomaa, V, Sethupathy, Praveen, Steinthorsdottir, V, Todd Green, Serrano-Ríos, Manuel, Province, MA, Eric J G Sijbrands, Shuldiner, A.R., Rudock, M.E., Lieverse, A, Elliott, Katherine S, Magnusson, PK, Uda, Manuela, Isomaa, Bo, Prokopenko, Inga, Francis S Collins, Bergmann, Sven, Amy J Swift, Hofmann, Oliver M, Eleftheria Zeggini, Neville, MJ, Jacqueline Witteman, Paolisso, G., Kanoni, S., Scuteri, A., Hunter, David J, Sparsø, Thomas, Ariyurek, Y., Mukherjee, Sutapa, Crisponi, Laura, Chines, Peter S, Maria R Wing, Hitman, Graham A, Henneman, Peter, Rotter, Jerome I, Nicholas J Wareham, Claudia Langenberg, Joe Hung, Bong H. Roh (190243), Bostrom, MA, Visvikis-Siest, Sophie, Goel, A., Bowden, Donald W., Hicks, PJ, Udo Seedorf, Vincent Mooser, Uitterlinden, A, van Dijk, K.W., Julie T. Ziegler (190269), Lyssenko, V, Naitza, S, Bonnefond, A., Bostrom, M.A., Sale, Michele M, Bravenboer, B., Forouhi, Nita G, Marmot, M., Laakso M, Hicks, P., Adeyemo, Adebowale, Palmer, Nicholette D., Grarup, Niels, Luigi Ferrucci, Crawford, Gabe, Morris, A.D., H-Erich Wichmann, Hester, J., Caitrin W. McDonough (190241), Hicks PJ, Rocheleau, G, van Dam, R.M., Kesaniemi, Y Antero, Yvonne Böttcher, Hester, JM, Anna L Gloyn, Bruce M Psaty, Jula, A, Freedman, B.I., Nita G Forouhi, Sampson, Michael J, McCarthy, M.I., Penninx, B.W., John F Peden, Raychaudhuri, S., Polasek, O., Charpentier, Guillaume, Koskinen, S., Uitterlinden, A., Posthuma, Danielle, Tichet, J., Jean Tichet, Stein, L.D., David Altshuler, Syvänen, AC, Deloukas, Panos, Lind, L, Ardlie, K., Megan E. Rudock (190251), Abecasis, GR, Petersen, AK, Karpe, Fredrik, Elliott, K.S., Angela Silveira, Zhao, J.H., Bouatia-Naji, N, Vitart, V, Ziegler, J.T., Hayward, C, Jasmin Divers (171577), Coin, Lachlan J M, Kanoni, Stavroula, Koskinen S, Glazer, N.L., Bostrom, M., Annelli Sandbaek, Bravenboer, B, Burtt, Noël P, Spector, TD, Delplanque, J., Goodarzi, MO, Igor Rudan, Lewis, Joshua P., Nicole Vogelzangs, Roh, B.H., Benjamin F Voight, Paul Scheet, Talbert Matthew E., Robert Mahley, Ferrucci, L., Hartikainen, A.L., Ardlie, K, Talbert, ME, David Melzer, Jørgensen, Torben, Hveem, Kristian, Spranger, Joachim, Kesaniemi, YA, Manning, AK, Sophie Visvikis-Siest, Buchanan, T.A., Tönjes, A, Hester Jessica M., Peden, JF, Witteman, Jacqueline, S Sandy An, Magnusson, P.K., Kaakinen, M, Benediktsson, R, Bumpstead, Suzannah, Ruth McPherson, Pierre Meneton, Hassanali, N., Sigurdsson, Gunnar, Elliott, A., Cornelis, Marilyn, Cisca Wijmenga, Campbell, H, Bouatia-Naji, Nabila, Hartikainen AL, Langenberg, Claudia, Watkins, H, Lincoln D Stein, Elliott, AL, Ferrucci, Luigi, Paul W Franks, Matthew N Cooper, Eric Sijbrands, Cooper, C., Sijbrands, Eric J G, Michael Stumvoll, Ward, Kim L, Matthew E Talbert, Franklin, CS, Niels Grarup, Talbert, M., Day, IN, Sandbaek, A., Roden, Michael, Kraft, P, Pouta, Anneli, Lieverse, A., Kao, W H Linda, Pouta A, Meneton, Pierre, Anke Tönjes, Shrader, Peter, Gieger, C., Siscovick, DS, Zeggini, Eleftheria, Jürgen Graessler, Green, Todd, Province, M.A., David Meyre, Shah Ebrahim, Sven Bergmann, Lathrop, GM, Gudmar Thorleifsson, Grallert, Harald, Cyrus Cooper, Zabena, Carina, Daly, Mark J, Sparsø, T., Altshuler, D, Lawlor, DA, John P Beilby, Clarke, Robert, Sun, Qi, Waterworth, D.M., Mangino, Massimo, de Geus, E.J.C.; id_orcid, Irene Pichler, Lyle J Palmer, Lu, L., Wild, S.H., Wing Maria R., Clarke, R., Gonneke Willemsen, Christopher J Groves, Rudock, Megan E., Rybin, D., Hassanali, Neelam, Tichet, J, Ferreira, T, Zhai, Guangju, James F Wilson, van Herpt, T, Chines, Peter, Midthjell, K., Stefansson, K., Forouhi, N.G., Hallmans, G., Rayner, N William, Meyre, David, Alan F Wright, Ward, K.L., Visvikis-Siest, S, Scheet, P, Johanna Kuusisto, Massimo Mangino, Saxena, Richa, Rosa Maria Roccasecca, Nathan, David M, Sun, Q., Willemsen, G, Caroline Hayward, Boomsma, D.I.; id_orcid, Mukherjee, S., Navarro, Pau; id_orcid, Proença, C, Harry Campbell, Andrew Walley, Sethupathy, P., Bert Bravenboer, John W G Yarnell, Cavalcanti-Proença, C., Scuteri, A, Bowden, DW, Cooper, MN, Ben A Oostra, Veronique Vitart, Proença, Christine, Saxena, R., Rivadeneira, F., Meredith A. Bostrom (190249), Angelo Scuteri, Mooser, V, Rudan, Igor, Sigurdsson, G., Song, K., Jarred B McAteer, Griffin, S, Smith, George Davey, O'Connell, J, Syddall, H., An, S Sandy, Nancy L Pedersen, Rice, K, Inês Barroso, Ingrid B Borecki, Ko Willems van Dijk, Rotimi Charles N., Lu, L.Y., Ben-Shlomo, Yoav, Huth, Cornelia, Andrew D Morris, Potter, SC, Wijmenga, Cisca, Weedon, Michael N, Sovio, U., Freedman, Barry I., Johnson, Toby, Ghislain Rocheleau, Salomaa V, Divers, J., Simpson, L., Spranger, J., Lawlor, Debbie A, Meitinger, T, André G Uitterlinden, Ferrara, , Assiamira, Han, X., Syddall, Holly, Pankow, JS, Day, Ian NM, Thorsteinsdottir, U., Boomsma, DI, Zelenika, D., Cécile Lecoeur, Lu, L, Mohlke, KL, Palmer ND, Rocheleau, G., Martínez-Larrad, M.T., Cavalcanti-Proença, C, Cooper, C, Uitterlinden, A.G., Antje Fischer-Rosinsky, Sarah H Wild, Penninx, Brenda W J H, Hicks, Pamela, Philippe Froguel, Shriner, D., Goodarzi, M.O., Pankow, James S, Serrano-Ríos, M, Wing, Maria R., Psaty, BM, Zeggini, E., Walker, M., Willemsen, G., McPherson, Ruth, Tuomi, T, Cao, Antonio, Lajunen, T, Dupuis, J., Lindgren, C.M., Bennett, AJ, Glazer, Nicole L, Rybin, Denis, Smith, NL, Jaakko Kaprio, Boomsma, D.I., Psaty, B.M., Ulla Sovio, Hansen, Torben, Hofman, A, Dina, C, Sovio, Ulla, Proença, C., Franklin, C.S., Perry, John R B, van Hoek, Mandy, Frayling, T.M., Pramstaller, Peter P, Rudan, I, Wu, G., Narisu, N, Blagieva, R, Vitart, V., Boström, KB, Pedersen, O, Kyvik, K.O., Cooper, Cyrus, Lachlan J M Coin, Jouke Jan Hottenga, Wing, M.R., Sayer, Avan Aihie, Pilar Galan, Katharine R Owen, Michele M. Sale (3944525), Hayward, Caroline; id_orcid, Jian'an Luan, Henneman, P., Diana Zelenika, Polasek, O, Sun, Q, Samuli Ripatti, Hamsten, Anders, Henneman, P, Loos, Ruth JF, Zethelius, B, Seedorf, Udo, Sladek, Rob, Boehnke, M., McDonough Caitrin W., Wu, Guanming, Silander, K, Jasmin Divers, Singleton, A, McCarthy, Mark I, van Herpt, T., Karpe, F, Kivimäki M, Palmer, N.D., Michael J Sampson, Ng, M.C., Mangino, M., Ruokonen, A., Griffin, S., Franks, P.W., Kuusisto, J, Zabena, C, Bonnycastle, LL, Sanna, S., Nicole L Glazer, Silander, K., Rybin, D, Cavalcanti-Proença, Christine, Lyssenko, V., Hung, J., Groop, L., Eco J C de Geus, Torben Jørgensen, Walker, M, Kyvik, Kirsten Ohm, Loos, Ruth J F, Hugh Watkins, Roccasecca, RM, Rob M van Dam, Pearson, D, Simpson, L, Kim L Ward, Zethelius, B., Carina Zabena, Stephane Cauchi, Altshuler, D., Borch-Johnsen, K., Timpson, Nicholas J, Hofman, A., Lu Qi, Marika Kaakinen, Manjinder Sandhu, Watanabe, R.M., Meisinger, Christa, Beverley M Shields, Valgerdur Steinthorsdottir, Jarvelin, Marjo-Riitta, Cecilia M Lindgren, Melzer, D, Perola M, Franzosi, Maria Grazia, Böttcher, Y., Markku Laakso, Barter, P., Praveen Sethupathy, Bergman, R.N., Roden, M, Martínez-Larrad, MT, Cauchi, Stephane, Salomaa, Veikko, Collins, Francis S, Laakso, M, Hillman, David R, Ingelsson, Erik, Eleanor Wheeler, Fischer-Rosinsky, Antje, Lauritzen, T, Avan Aihie Sayer, Abbas Dehghan, Rudock Megan E., de Geus, EJ, McCarthy, MI, Kao, WH Linda, Ping An, Manuel Serrano-Ríos, Gyllensten, U., Shields, B, Doney, Alex S F, Jessica N. Cooke (190248), Saxena, R, Shields, Beverley, Melzer, David, Thomas Illig, Giuseppe Paolisso, Michael Marmot, Crawford, G., Roza Blagieva, Hide, W.A., DIAGRAM Consortium (Huth, C. ; Grallert, H. ; Gieger, C. ; Klopp, N. ; Meitinger, T. ; Petersen, A.-K. ; Wichmann, H.-E. ; Illig, T.), Scuteri, Angelo, Andrew A Hicks, Cornelis, M, Sandy An, S, Huth, C., Michael Roden, Fernando Rivadeneira, Debbie A Lawlor, George Davey Smith, Norman Klopp, Sijbrands, Eric JG, Varma, D, Spranger, J, Sladek, Robert, Uitterlinden, Andre, Martínez-Larrad, María Teresa, Mangino, M, An, P., Robertson, NR, Silvia Naitza, Kovacs, P., Herder, C., Thorand, Barbara, Kyvik, Kirsten Ohm; id_orcid, Hunter, DJ, Simon Griffin, DIAGRAM Consortium, Wagner, PJ, Colin N A Palmer, Rob Sladek +999 morecore +2 more sourcesDesign and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş +5 morewiley +1 more sourceGene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease
PLoS ONE, 2014 Background Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, using an V. Escott-Price, C. Bellenguez, Li-San Wang, S. Choi, D. Harold, L. Jones, P. Holmans, A. Gerrish, Alexey Vedernikov, A. Richards, A. Destefano, J. Lambert, C. Ibrahim-Verbaas, A. Naj, R. Sims, G. Jun, J. Bis, G. Beecham, B. Grenier-Boley, G. Russo, T. Thornton-Wells, N. Denning, A. Smith, V. Chouraki, C. Thomas, M. Ikram, D. Zélénika, B. Vardarajan, Y. Kamatani, Chiao-Feng Lin, H. Schmidt, Brian W. Kunkle, Melanie L. Dunstan, M. Vronskaya, Andrew D. Johnson, A. Ruiz, M. Bihoreau, C. Reitz, F. Pasquier, P. Hollingworth, O. Hanon, A. Fitzpatrick, J. Buxbaum, D. Campion, P. Crane, C. Baldwin, T. Becker, V. Gudnason, C. Cruchaga, D. Craig, N. Amin, C. Berr, O. Lopez, P. De Jager, V. Deramecourt, J. Johnston, D. Evans, S. Lovestone, L. Letenneur, I. Hernández, D. Rubinsztein, G. Eiriksdottir, K. Sleegers, A. Goate, N. Fiévet, M. Huentelman, M. Gill, Kristelle S. Brown, M. Kamboh, L. Keller, P. Barberger-Gateau, B. McGuinness, E. Larson, Amanda J. Myers, C. Dufouil, S. Todd, D. Wallon, S. Love, E. Rogaeva, J. Gallacher, P. S. St George-Hyslop, J. Clarimón, A. Lleó, A. Bayer, D. Tsuang, Lei Yu, M. Tsolaki, P. Bossù, G. Spalletta, P. Proitsi, J. Collinge, S. Sorbi, F. S. García, Nick C Fox, J. Hardy, M. Naranjo, P. Bosco, R. Clarke, C. Brayne, D. Galimberti, E. Scarpini, U. Bonuccelli, M. Mancuso, G. Siciliano, S. Moebus, P. Mecocci, M. Del Zompo, W. Maier, H. Hampel, A. Pilotto, A. Frank-García, F. Panza, V. Solfrizzi, P. Caffarra, B. Nacmias, William R. Perry, M. Mayhaus, L. Lannfelt, H. Hakonarson, S. Pichler, M. Carrasquillo, M. Ingelsson, D. Beekly, V. Álvarez, F. Zou, Otto Valladares, S. Younkin, E. Coto, K. Hamilton-Nelson, W. Gu, C. Razquín, P. Pastor, I. Mateo, M. Owen, K. Faber, P. Jónsson, O. Combarros, M. O'Donovan, Laura B. Cantwell, H. Soininen, D. Blacker, S. Mead, T. Mosley, D. Bennett, T. Harris, L. Fratiglioni, C. Holmes, Renée de Bruijn, P. Passmore, T. Montine, K. Bettens, J. Rotter, A. Brice, K. Morgan, T. Foroud, W. Kukull, D. Hannequin, J. Powell, M. Nalls, K. Ritchie, K. Lunetta, J. Kauwe, E. Boerwinkle, M. Riemenschneider, M. Boada, M. Hiltunen, E. Martin, R. Schmidt, D. Rujescu, J. Dartigues, R. Mayeux, C. Tzourio, A. Hofman, M. Nöthen, C. Graff, B. Psaty, J. Haines, M. Lathrop, M. Pericak-Vance, L. Launer, C. van Broeckhoven, L. Farrer, C. M. van Duijn, A. Ramírez, S. Seshadri, G. Schellenberg, P. Amouyel, Julie Williams +187 moresemanticscholar +1 more sourcers1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. [PDF]
, 2007 The IL23R gene has been identified as a susceptibility gene for inflammatory bowel disease (IBD) in the North American population. The aim of our study was to test this association in a large German IBD cohort and to elucidate potential interactions with Folwaczny, Christian, Seiderer Julia, Ochsenkühn, Thomas, Klein, Wolfram, Griga Thomas, Schiemann Uwe, Folwaczny Matthias, Tonenchi, Laurian, Matthias Folwaczny, Bertram Müller-Myhsok, Schmechel, Silke, Jörg T Epplen, Epplen Jörg T., Jörg T. Epplen, Mussack, Thomas, Schiemann, Uwe, Pfennig Simone, Kerstin Maier, Brand, Stephan, Brand Stephan, Thomas Ochsenkühn, Török, Helga-Paula, Epplen, Jörg T., Thomas Griga, Konrad, Astrid, Müller-Myhsok Bertram, Astrid Konrad, Göke, Burkhard, Konrad Astrid, Wetzke Martin, Schmechel Silke, Epplen, Jörg T, Griga, Thomas, Folwaczny, Matthias, Pfennig, Simone, Peter Lohse, Folwaczny Christian, Seiderer, Julia, Török Helga-Paula, Julia Dambacher, Uwe Schiemann, Glas, Jürgen, Mussack Thomas, Silke Schmechel, Ochsenkühn Thomas, Grassl, Christine, Müller-Myhsok, Bertram, Tonenchi Laurian, Christian Folwaczny, Martin Wetzke, Dambacher Julia, Burkhard Göke, Helga-Paula Török, Göke Burkhard, Stephan Brand, Maier Kerstin, Dambacher, Julia, Jürgen Glas, Maier, Kerstin, Klein Wolfram, Wetzke, Martin, Laurian Tonenchi, Christine Grassl, Lohse, Peter, Thomas Mussack, Simone Pfennig, Wolfram Klein, Glas Jürgen, Lohse Peter, Julia Seiderer, Grassl Christine, Schiemann, Uwe Kurt +71 morecore +2 more sourcesMicrobiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille +3 morewiley +1 more sourceMultiple type 2 diabetes susceptibility genes following genome-wide association scan in UK samples
Science, 2007 The molecular mechanisms involved in the development of type 2 diabetes are poorly understood. Starting from genome-wide genotype data for 1924 diabetic cases and 2938 population controls generated by the Wellcome Trust Case Control Consortium, we set ...E. Zeggini, M. Weedon, C. Lindgren, T. Frayling, K. Elliott, H. Lango, N. Timpson, John R. B. Perry, N. W. Rayner, R. Freathy, J. Barrett, B. Shields, A. Morris, S. Ellard, C. Groves, L. Harries, J. Marchini, K. Owen, B. Knight, L. Cardon, M. Walker, G. Hitman, A. D. Morris, A. Doney, M. McCarthy, A. Hattersley +25 moresemanticscholar +1 more sourceThe role of vascular and hormonal genes in migraine susceptibility
, 2006 Migraine is a primary headache disorder that involves both genetic and environmental components. Migraine is considered to be a polygenic disorder with a number of susceptibility genes having a minor but nonetheless significant impact on susceptibility ...Griffiths, Lyn R, Quinlan, Sharon, Colson, Natalie J., Griffiths, Lyn R., Lea, Rod A, Colson, Natalie J, Lea, Rod A. +6 morecore +1 more source
