Results 61 to 70 of about 583,132 (315)

Analysis of IL12B gene variants in inflammatory bowel disease [PDF]

, 2012
IL12B encodes the p40 subunit of IL-12, which is also part of IL-23. Recent genome-wide association studies identified IL12B and IL23R as susceptibility genes for inflammatory bowel disease (IBD).
Darina Czamara, Seiderer, J., Seiderer Julia, Ochsenkühn, Thomas, Fries, C., Julia Seiderer (107820), Beigel, F., Wagner, Johanna, Glas, J., Cornelia Tillack (174718), Friedrich, Matthias, Christian Steib (174731), Czamara, D., Diegelmann Julia, Jürgen Glas (107816), Fries Christoph, Tillack, Cornelia, Friedrich Matthias, Steib Christian, Stallhofer, Johannes, Torsten Olszak (107835), Brand, Stephan, Göke, B., Florian Beigel (174724), Brand Stephan, Thomas Ochsenkühn, Olszak Torsten, Beigel, Florian, Matthias Friedrich (174721), Thomas Ochsenkühn (174734), Stallhofer, J., Ochsenkühn, T., Johannes Stallhofer, Matthias Friedrich, Wetzke, M., Darina Czamara (107824), Stephan Brand (107861), Cornelia Tillack, Julia Diegelmann, Beigel Florian, Steib, Christian, Göke, Burkhard, Wetzke Martin, Fries, Christoph, Wagner, J., Friedrich, M., Seiderer, Julia, Glas, Jürgen, Diegelmann, J., Burkhard Göke (109829), Christoph Fries, Ochsenkühn Thomas, Wagner Johanna, Martin Wetzke, Burkhard Göke, Göke Burkhard, Christian Steib, Stephan Brand, Brand, S., Steib, C., Czamara, Darina, Martin Wetzke (107833), Stallhofer Johannes, Julia Diegelmann (107830), Jürgen Glas, Johanna Wagner (174709), Tillack Cornelia, Johanna Wagner, Wetzke, Martin, Czamara Darina, Diegelmann, Julia, Christoph Fries (174714), Johannes Stallhofer (174728), Glas Jürgen, Torsten Olszak, Olszak, T., Florian Beigel, Julia Seiderer, Olszak, Torsten, Tillack, C.   +79 more
core   +1 more source

Disease spectrum of gastric cancer susceptibility genes [PDF]

, 2021
Pathogenic variants in germline cancer susceptibility genes can increase the risk of a large number of diseases. Our study aims to assess the disease spectrum of gastric cancer susceptibility genes and to develop a comprehensive resource of gene–disease ...
Hughes, Kevin S., Braun, Danielle, Mullen, John T., Yin, Kanhua, McKinley, Sophia K., Pathak, Kush, McKinley, Sophia K, Bao, Yujia, Singh, Preeti, Mullen, John T, Zhou, Jingan, Hughes, Kevin S, Wang, Jin, Wu, Menghua   +13 more
core   +1 more source

A Transcriptome‐Wide Association Study Identifies Candidate Susceptibility Loci and Genes for Lung Cancer Risk

Cancer Medicine
Background Genome‐wide association studies (GWAS) have identified over 80 susceptibility loci for lung cancer risk. However, the genes underlying these associations remain largely unknown. Methods We conducted a large transcriptome‐wide association study
Tianying Zhao, Jiajun Shi, Yaohua Yang, Dan Zhou, Jie Ping, Shuai Xu, Lili Xu, Jie Wu, Xiao‐Ou Shu, Ran Tao, Bingshan Li, Wei Zheng, Jirong Long, Qiuyin Cai   +13 more
doaj   +1 more source

Immunoglobulin Depletion and Recovery Following Blinatumomab in Infants With KMT2A‐Rearranged ALL

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Adding blinatumomab to standard chemotherapy for infants with KMT2A‐rearranged acute B‐cell lymphoblastic leukemia (KMT2A‐r B‐ALL) improves outcomes. Although blinatumomab impairs immunoglobulin G (lgG) production, increasing infection susceptibility, IgG recovery remains poorly understood.
Miguel Vieira Martins, Paola de Lorenzo, Rishi S. Kotecha, Andishe Attarbaschi, Gabriele Escherich, Karsten Nysom, Jan Stary, Alina Ferster, Benoit Brethon, Franco Locatelli, Martin Schrappe, Peggy E. Scholte‐van Houtem, Maria G. Valsecchi, Rob Pieters, Inge M. van der Sluis   +14 more
wiley   +1 more source

A genome-wide association search for type 2 diabetes genes in African Americans [PDF]

, 2011
African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity.
Bostrom, Meredith A, Ingelsson, E., Shields, B.M., Fischer-Rosinsky, A., Sanna, Serena, Roh, BH, Boerwinkle, E., Anneli Pouta, Qi, L., Hicks, Andrew A, Fedson, A.C., Palmer, L.J., Laura J McCulloch, Fedson, AC, Cao, A, Lajunen, T., Glazer, NL, Toshiko Tanaka, Peter Shrader, Kao, Wen H L, Tiinamaija Tuomi, Couper, DJ, Christine Cavalcanti-Proença, Steven A McCarroll, Kaprio, Jaakko, Navarro, Pau, Hammond, Naomi, Roh, B., Antti Jula, Qi, Lu, Soumya Raychaudhuri, Palmer, CN, Uitterlinden, André G, Perry, J.R., Thomas A Buchanan, Syvänen, A.C., Barroso, Inês, Divers Jasmin, Boehm, Bernhard O, Qi Sun, Stefansson, K, Johnson, Paul RV, Benediktsson, R., Dedoussis, GV, de Geus, E.J., Ardlie, Kristin, Nigel W Rayner, Kong, A., Eric Brunner, Qi, L, Michael A Province, de Geus, Eco J C, Denis Rybin, Smith, GD, Hallmans, Göran, Rivadeneira, F, Meigs, JB, Meredith A Bostrom, Ganser, M, Raychaudhuri, Soumya, Antonio Cao, Visvikis-Siest, S., Zethelius, Björn, Johnson, T, Alisa K Manning, Steve A McCarroll, Jula A, Patrik K E Magnusson, Penninx, B.W.J.H., Syddall, H, Jarvelin MR, Freedman, BI, Platou, Carl Geoffrey Parrinder, Jessica M. Hester (190247), Pattou, F., Peter S Chines, et al., Lajunen, Taina, Peter Henneman, Sladek, R, Nicholette D. Palmer (190239), Doney, A., Vitart, Veronique, Herder, C, Hercberg, S., James S Pankow, Morris, AD, Doney, AS, Katherine S Elliott, Morris, AP, Wright, A.F., Magnusson, Patrik KE, Jaakko Tuomilehto, Robertson, N.R., Dupuis, Josée, Pfeiffer, Andreas F H, Graessler, J, Wareham, N.J., Holly Syddall, Li, Y., Ulf Gyllensten, Joshua P Lewis, Silveira, Angela, Heath, SC, Franzosi, MG, Pfeiffer, A.F., Valeriya Lyssenko, Seedorf, U, Böttcher, Yvonne, Josée Dupuis, Stavroula Kanoni, Doney, Alex SF, Illig, T., Galan, P., Pedersen, Nancy L, Gabe Crawford, Bowden Donald W., Brunner, Eric, Andrew P Morris, Jackson, A.U., Laila Simpson, Marre, M, Knight, Beatrice, Wilson, James F, Dupuis, J, Pamela J Hicks, Jennie Hui, Ian N M Day, Yun Li, van Dam, Rob M, Jaqueline C M Witteman, Bornstein, SR, Bostrom, Meredith A., Lu Lingyi, Ripatti, S., Hung, J, Ng Maggie C. Y., Waterworth, DM, Ruokonen, Aimo, Wright, AF, Hottenga, J.J., Aulchenko, Y.S., Wu, G, Palmer, LJ, Hercberg, Serge, Pakyz, R, Hicks, A.A., Sijbrands, EJ, Boehm, B.O., Blagieva, R., Waterworth, Dawn M, Thorsteinsdottir, U, Polasek, Ozren, M Carola Zillikens, Ruth J F Loos, Shriner, D, Jarvelin, MR, Cooke, J., Brenda W J H Penninx, Aroon D Hingorani, Elliott, KS, Sijbrands, E., Guanming Wu, Borch-Johnsen, Knut, Hillman, D.R., Sale Michele M., Jackson, Anne U, Brunner, E, Cooke, JN, Paul R V Johnson, Ferreira, T., Yarnell, JW, Amy Swift, Tuomilehto J, Collins, FS, George V Dedoussis, Ruokonen, A, Zhao, JH, Egan, J.M., Timon W van Haeften, Kivimaki, M., Knut Borch-Johnsen, Pramstaller, PP, Langefeld, Carl D., Tuomi, T., Cooke, Jessica N, Vollenweider, P, Elliott, P., Peter Paul Pramstaller, Owen, KR, Wheeler, Eleanor, Rolandsson, Olov,, Silander K, Suzannah J Bumpstead, Roh, Bong H, Aimo Ruokonen, Tanaka, T, Griffin, Simon, Marjo-Riitta Jarvelin, Spector, Timothy D, Richard N Bergman, van Haeften, TW, Dawn M Waterworth, Ganser, M., Mägi, R., Beilby, John P, Smith, N.L., Walters, G Bragi, Tichet, Jean, Tuomilehto, J., Swift, Amy J, Galan, P, Jørgensen, T., Serge Hercberg, Kenneth Rice, Deloukas, P, María Teresa Martínez-Larrad, An, P, Hansen, T., Serena Sanna, Pearson, D., Paolisso, G, Andreas F H Pfeiffer, Josephine M Egan, Sijbrands, E, Robertson, Neil R, Mohlke, K.L., Beatrice Knight, Sethupathy, P, Campbell, Harry, Bennett, A.J., Rhian Gwilliam, Song, K, Rolandsson, O, Voight, Benjamin F, Heath, S.C., Dorret I Boomsma, Leena Peltonen, Magnusson, Patrik K E, Bochud, M., Bergmann, S, Gloyn, A.L., Grallert, H., Shriner Daniel, Kari Stefansson, Zeggini, E, Hadjadj, S, Charles N Rotimi, Steinthorsdottir, V., Hartikainen, AL, Florez, Jose C, Wagner, Peter J, Rafn Benediktsson, Ripatti, S, Lindgren, Cecilia M, Danielle Posthuma, Bong H Roh, Adeyemo, A, Mark O Goodarzi, Smith, G.D., François Pattou, Palmer, N., Timothy M Frayling, Wing, Maria R, Fox, C.S., Oliver M Hofmann, Freedman Barry I., Guangju Zhai, Palmer, Colin N A, Torben Hansen, Zelenika, D, Li, M., Thorand, B, Langefeld, C.D., Franklin, Christopher S, Watanabe, RM, Manning, Alisa K, Yavuz Ariyurek, Walley, A, Wilson, J.F., Pedersen, NL, Pedersen, O., Posthuma, D., Beilby, JP, Palmer, ND, Gwilliam, R, Soranzo, N., Brunner, E., Seedorf, U., Waeber, G., Winston A Hide, Pouta, A., Perry, JR, Ferrara, A, Wichmann, HE, Boström, Kristina Bengtsson, Segrè, A.V., Pichler, Irene, Silander, Kaisa, Wilson, James F; id_orcid, Peter J Wagner, Kovacs, P, Le Bacquer, O, Kaprio, J, Egan, Josephine M, Bergmann, S., Marco Orrù, Johnson, Paul R V, Candace Guiducci, Frayling, Timothy M, Ng, Maggie C. Y., Posthuma, D.; id_orcid, Illig, T, Jerome I Rotter, McDonough, Catrin W, Cristen J Willer, de Geus, E.J.C., Willemsen, G.; id_orcid, Prokopenko, I, Payne, Felicity, Ganser, Martha, Navarro, P., Day, I.N., Kristian Hveem, Hattersley, Andrew T, Florez, JC, Kaisa Silander, Kovacs, Peter, Reedik Mägi, Michael N Weedon, Grarup, N., Hayward, Caroline, Schwarz, Peter, van Vliet-Ostaptchouk, Jana V, Albert Hofman, Kaakinen, M., Amanda J Bennett, Voight, B.F., Lingyi Lu, Rotimi, C.N., Olov Rolandsson, Göran Hallmans, Hottenga, Jouke Jan, Hicks, AA, Megan E Rudock, Kuusisto, Johanna, An, Ping, Adeyemo, A., McDonough CW, Weedon, MN, Barter, Philip, Oostra, B.A., Rayner, NW, Elliott, Amanda, Watkins, Hugh, Christian Gieger, Buchanan, Thomas A, Daniel Shriner (137188), Amanda L Elliott, Christine Proença, Divers, J, Morken, Mario A, Lathrop, G.M., Samy Hadjadj, Kristin Ardlie, Song, Kijoung, Michael Boehnke, Spector, T.D., Sijbrands, E.J., Elliott, Amanda L, Taina Lajunen, Scott, LJ, Hicks, P.J., Jessica N Cooke, McDonough, C., Wilson, JF, Forouhi, NG, Dina, Christian, Bumpstead, S.J., Waeber, G, Shields, B., Aulchenko, Yurii S, Perry, John RB, Jose C Florez, Province, Michael A, Peter Nilsson, Carl D Langefeld, Raychaudhuri, S, Carl Platou, Williams, G.H., Robert Sladek, Crisponi, L., Gloyn, AL, Petersen, Ann-Kristin, McDonough, CW, Shields, BM, Paolisso, Giuseppe, Zillikens, MC, Leif Groop, Hadjadj, Samy, Couper, D.J., Goncalo R Abecasis, Bumpstead, S, McPherson, R., Erdos, Michael R, Braxton D Mitchell, Froguel, P., Peter Kovacs, Timpson, N.J., Matthew J Neville, Froguel, P, Fox, Caroline S, Sutapa Mukherjee, Rocheleau, Ghislain, Johnson, PR, Uda, M., Pedersen, Oluf, Mark Walker, Wheeler, E., Groop, L, Boehnke, M, Sanna, S, Isomaa, B., Hillman, DR, Wing, Maria, Hitman, G.A., Assiamira Ferrara, Peltonen, L, Kaakinen M, Owen, Katharine R, Hu, F.B., Sharp, SJ, Cooper, Matthew N, Langenberg, C, Owen, K.R., Strassburger, Klaus, Tuomi T, McCulloch, Laura J, Bostrom, Meredith, Swift, A.J., Simon C Potter, Joshua P. Lewis (190257), Cao, A., Waeber, Gérard, Sijbrands, Eric, Bochud, Murielle, Jana V van Vliet-Ostaptchouk, Lind, Lars, Palmer, Colin NA, Ebrahim, S., Hveem, K., Navarro, P, Le Bacquer, Olivier, van Dijk, KW, Kong, Augustine, Kesaniemi YA, Wagner, P.J., Mooser, Vincent, Uitterlinden, AG, Sovio, U, Joshua Randall, Gieger, C, Pakyz, Ruth, Mandy van Hoek, van Vliet-Ostaptchouk, JV, Gérard Waeber, Wichmann, H-Erich, Marmot, M, Welch, R.P., Matthew E. Talbert (190255), Goel, Anuj, Watkins, H., Pfeiffer, Andreas FH, Timothy D Spector, Schlessinger, D., Isomaa, B, Narisu, N., Seppo Koskinen, Ziegler Julie T., Chines, P.S., van Duijn, CM, Graessler, J., Pramstaller, Peter Paul, Sparsø, T, MAGIC Consortium,, Langefeld, CD, Campbell, Harry; id_orcid, Jarvelin, M.R., Blagieva, Roza, Scott Grundy, Singleton, Andrew, Johnson, T., Salomaa, V, Sethupathy, Praveen, Steinthorsdottir, V, Todd Green, Serrano-Ríos, Manuel, Province, MA, Eric J G Sijbrands, Shuldiner, A.R., Rudock, M.E., Lieverse, A, Elliott, Katherine S, Magnusson, PK, Uda, Manuela, Isomaa, Bo, Prokopenko, Inga, Francis S Collins, Bergmann, Sven, Amy J Swift, Hofmann, Oliver M, Eleftheria Zeggini, Neville, MJ, Jacqueline Witteman, Paolisso, G., Kanoni, S., Scuteri, A., Hunter, David J, Sparsø, Thomas, Ariyurek, Y., Mukherjee, Sutapa, Crisponi, Laura, Chines, Peter S, Maria R Wing, Hitman, Graham A, Henneman, Peter, Rotter, Jerome I, Nicholas J Wareham, Claudia Langenberg, Joe Hung, Bong H. Roh (190243), Bostrom, MA, Visvikis-Siest, Sophie, Goel, A., Bowden, Donald W., Hicks, PJ, Udo Seedorf, Vincent Mooser, Uitterlinden, A, van Dijk, K.W., Julie T. Ziegler (190269), Lyssenko, V, Naitza, S, Bonnefond, A., Bostrom, M.A., Sale, Michele M, Bravenboer, B., Forouhi, Nita G, Marmot, M., Laakso M, Hicks, P., Adeyemo, Adebowale, Palmer, Nicholette D., Grarup, Niels, Luigi Ferrucci, Crawford, Gabe, Morris, A.D., H-Erich Wichmann, Hester, J., Caitrin W. McDonough (190241), Hicks PJ, Rocheleau, G, van Dam, R.M., Kesaniemi, Y Antero, Yvonne Böttcher, Hester, JM, Anna L Gloyn, Bruce M Psaty, Jula, A, Freedman, B.I., Nita G Forouhi, Sampson, Michael J, McCarthy, M.I., Penninx, B.W., John F Peden, Raychaudhuri, S., Polasek, O., Charpentier, Guillaume, Koskinen, S., Uitterlinden, A., Posthuma, Danielle, Tichet, J., Jean Tichet, Stein, L.D., David Altshuler, Syvänen, AC, Deloukas, Panos, Lind, L, Ardlie, K., Megan E. Rudock (190251), Abecasis, GR, Petersen, AK, Karpe, Fredrik, Elliott, K.S., Angela Silveira, Zhao, J.H., Bouatia-Naji, N, Vitart, V, Ziegler, J.T., Hayward, C, Jasmin Divers (171577), Coin, Lachlan J M, Kanoni, Stavroula, Koskinen S, Glazer, N.L., Bostrom, M., Annelli Sandbaek, Bravenboer, B, Burtt, Noël P, Spector, TD, Delplanque, J., Goodarzi, MO, Igor Rudan, Lewis, Joshua P., Nicole Vogelzangs, Roh, B.H., Benjamin F Voight, Paul Scheet, Talbert Matthew E., Robert Mahley, Ferrucci, L., Hartikainen, A.L., Ardlie, K, Talbert, ME, David Melzer, Jørgensen, Torben, Hveem, Kristian, Spranger, Joachim, Kesaniemi, YA, Manning, AK, Sophie Visvikis-Siest, Buchanan, T.A., Tönjes, A, Hester Jessica M., Peden, JF, Witteman, Jacqueline, S Sandy An, Magnusson, P.K., Kaakinen, M, Benediktsson, R, Bumpstead, Suzannah, Ruth McPherson, Pierre Meneton, Hassanali, N., Sigurdsson, Gunnar, Elliott, A., Cornelis, Marilyn, Cisca Wijmenga, Campbell, H, Bouatia-Naji, Nabila, Hartikainen AL, Langenberg, Claudia, Watkins, H, Lincoln D Stein, Elliott, AL, Ferrucci, Luigi, Paul W Franks, Matthew N Cooper, Eric Sijbrands, Cooper, C., Sijbrands, Eric J G, Michael Stumvoll, Ward, Kim L, Matthew E Talbert, Franklin, CS, Niels Grarup, Talbert, M., Day, IN, Sandbaek, A., Roden, Michael, Kraft, P, Pouta, Anneli, Lieverse, A., Kao, W H Linda, Pouta A, Meneton, Pierre, Anke Tönjes, Shrader, Peter, Gieger, C., Siscovick, DS, Zeggini, Eleftheria, Jürgen Graessler, Green, Todd, Province, M.A., David Meyre, Shah Ebrahim, Sven Bergmann, Lathrop, GM, Gudmar Thorleifsson, Grallert, Harald, Cyrus Cooper, Zabena, Carina, Daly, Mark J, Sparsø, T., Altshuler, D, Lawlor, DA, John P Beilby, Clarke, Robert, Sun, Qi, Waterworth, D.M., Mangino, Massimo, de Geus, E.J.C.; id_orcid, Irene Pichler, Lyle J Palmer, Lu, L., Wild, S.H., Wing Maria R., Clarke, R., Gonneke Willemsen, Christopher J Groves, Rudock, Megan E., Rybin, D., Hassanali, Neelam, Tichet, J, Ferreira, T, Zhai, Guangju, James F Wilson, van Herpt, T, Chines, Peter, Midthjell, K., Stefansson, K., Forouhi, N.G., Hallmans, G., Rayner, N William, Meyre, David, Alan F Wright, Ward, K.L., Visvikis-Siest, S, Scheet, P, Johanna Kuusisto, Massimo Mangino, Saxena, Richa, Rosa Maria Roccasecca, Nathan, David M, Sun, Q., Willemsen, G, Caroline Hayward, Boomsma, D.I.; id_orcid, Mukherjee, S., Navarro, Pau; id_orcid, Proença, C, Harry Campbell, Andrew Walley, Sethupathy, P., Bert Bravenboer, John W G Yarnell, Cavalcanti-Proença, C., Scuteri, A, Bowden, DW, Cooper, MN, Ben A Oostra, Veronique Vitart, Proença, Christine, Saxena, R., Rivadeneira, F., Meredith A. Bostrom (190249), Angelo Scuteri, Mooser, V, Rudan, Igor, Sigurdsson, G., Song, K., Jarred B McAteer, Griffin, S, Smith, George Davey, O'Connell, J, Syddall, H., An, S Sandy, Nancy L Pedersen, Rice, K, Inês Barroso, Ingrid B Borecki, Ko Willems van Dijk, Rotimi Charles N., Lu, L.Y., Ben-Shlomo, Yoav, Huth, Cornelia, Andrew D Morris, Potter, SC, Wijmenga, Cisca, Weedon, Michael N, Sovio, U., Freedman, Barry I., Johnson, Toby, Ghislain Rocheleau, Salomaa V, Divers, J., Simpson, L., Spranger, J., Lawlor, Debbie A, Meitinger, T, André G Uitterlinden, Ferrara, , Assiamira, Han, X., Syddall, Holly, Pankow, JS, Day, Ian NM, Thorsteinsdottir, U., Boomsma, DI, Zelenika, D., Cécile Lecoeur, Lu, L, Mohlke, KL, Palmer ND, Rocheleau, G., Martínez-Larrad, M.T., Cavalcanti-Proença, C, Cooper, C, Uitterlinden, A.G., Antje Fischer-Rosinsky, Sarah H Wild, Penninx, Brenda W J H, Hicks, Pamela, Philippe Froguel, Shriner, D., Goodarzi, M.O., Pankow, James S, Serrano-Ríos, M, Wing, Maria R., Psaty, BM, Zeggini, E., Walker, M., Willemsen, G., McPherson, Ruth, Tuomi, T, Cao, Antonio, Lajunen, T, Dupuis, J., Lindgren, C.M., Bennett, AJ, Glazer, Nicole L, Rybin, Denis, Smith, NL, Jaakko Kaprio, Boomsma, D.I., Psaty, B.M., Ulla Sovio, Hansen, Torben, Hofman, A, Dina, C, Sovio, Ulla, Proença, C., Franklin, C.S., Perry, John R B, van Hoek, Mandy, Frayling, T.M., Pramstaller, Peter P, Rudan, I, Wu, G., Narisu, N, Blagieva, R, Vitart, V., Boström, KB, Pedersen, O, Kyvik, K.O., Cooper, Cyrus, Lachlan J M Coin, Jouke Jan Hottenga, Wing, M.R., Sayer, Avan Aihie, Pilar Galan, Katharine R Owen, Michele M. Sale (3944525), Hayward, Caroline; id_orcid, Jian'an Luan, Henneman, P., Diana Zelenika, Polasek, O, Sun, Q, Samuli Ripatti, Hamsten, Anders, Henneman, P, Loos, Ruth JF, Zethelius, B, Seedorf, Udo, Sladek, Rob, Boehnke, M., McDonough Caitrin W., Wu, Guanming, Silander, K, Jasmin Divers, Singleton, A, McCarthy, Mark I, van Herpt, T., Karpe, F, Kivimäki M, Palmer, N.D., Michael J Sampson, Ng, M.C., Mangino, M., Ruokonen, A., Griffin, S., Franks, P.W., Kuusisto, J, Zabena, C, Bonnycastle, LL, Sanna, S., Nicole L Glazer, Silander, K., Rybin, D, Cavalcanti-Proença, Christine, Lyssenko, V., Hung, J., Jorgensen, T, Groop, L., Eco J C de Geus, Torben Jørgensen, Walker, M, Kyvik, Kirsten Ohm, Loos, Ruth J F, Hugh Watkins, Roccasecca, RM, Rob M van Dam, Pearson, D, Simpson, L, Kim L Ward, Zethelius, B., Carina Zabena, Stephane Cauchi, Altshuler, D., Borch-Johnsen, K., Timpson, Nicholas J, Hofman, A., Lu Qi, Marika Kaakinen, Manjinder Sandhu, Watanabe, R.M., Meisinger, Christa, Beverley M Shields, Valgerdur Steinthorsdottir, Jarvelin, Marjo-Riitta, Cecilia M Lindgren, Melzer, D, Perola M, Franzosi, Maria Grazia, Böttcher, Y., Markku Laakso, Barter, P., Praveen Sethupathy, Bergman, R.N., Roden, M, Martínez-Larrad, MT, Cauchi, Stephane, Salomaa, Veikko, Collins, Francis S, Laakso, M, Hillman, David R, Ingelsson, Erik, Eleanor Wheeler, Fischer-Rosinsky, Antje, Lauritzen, T, Avan Aihie Sayer, Abbas Dehghan, Rudock Megan E., de Geus, EJ, McCarthy, MI, Kao, WH Linda, Ping An, Manuel Serrano-Ríos, Gyllensten, U., Shields, B, Doney, Alex S F, Jessica N. Cooke (190248), Saxena, R, Shields, Beverley, Melzer, David, Thomas Illig, Giuseppe Paolisso, Michael Marmot, Crawford, G., Roza Blagieva, Hide, W.A., DIAGRAM Consortium (Huth, C. ; Grallert, H. ; Gieger, C. ; Klopp, N. ; Meitinger, T. ; Petersen, A.-K. ; Wichmann, H.-E. ; Illig, T.), Scuteri, Angelo, Andrew A Hicks, Cornelis, M, Sandy An, S, Huth, C., Michael Roden, Fernando Rivadeneira, Debbie A Lawlor, George Davey Smith, Norman Klopp, Sijbrands, Eric JG, Varma, D, Spranger, J, Sladek, Robert, Uitterlinden, Andre, Martínez-Larrad, María Teresa, Mangino, M, An, P., Robertson, NR, Silvia Naitza, Kovacs, P., Herder, C., Thorand, Barbara, Kyvik, Kirsten Ohm; id_orcid, Hunter, DJ, Simon Griffin, DIAGRAM Consortium, Wagner, PJ   +999 more
core   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Genetic epidemiology of breast cancer in CYPRUS: A case -control study of DNA repair genes [PDF]

, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The occurrence of early-onset breast cancer (EOBC) has been associated with germline mutations in the BRCA1 and BRCA2 genes.
Loizidou, Maria, Liozidou, Maria
core  

Genes Influencing Susceptibility to Infection [PDF]

The Journal of Infectious Diseases, 2008
In this issue of the Journal, an article [1] reports the results of a human genome scan for quantitative trait loci (QTLs) influencing susceptibility to Ascaris lumbricoides.Theworkisimportantbothforthe insight that it provides into how the body resistsheavyinfectionwiththisimportant soil-transmitted intestinal helminth and for what it promises in this
William A , Petri, Beth D, Kirkpatrick, Rashidul, Haque, Priya, Duggal   +3 more
openaire   +2 more sources

The Study of Cancer Susceptibility Genes [PDF]

Cancers, 2021
“…most complex, new direction for cancer medicine is to integrate our understanding of aberrant genes and pathways to explain the behavior of cancer as a whole, thereby renewing the cycle of knowledge, discovery and therapeutic intervention [...]
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source