Results 61 to 70 of about 9,010,468 (307)
Unifying candidate gene and GWAS Approaches in Asthma. [PDF]
, 2010 The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS ...Heinzmann, Andrea, Ruether, Andreas, Otto Laub, Bufe, A., Lathrop, M, Schedel, M., Michel, Sven, Ruether, A., Michel, S., Schreiber, Stefan, von Berg, A., Gut, I.G., Christian Vogelberg, Ernst Rietschel, von Mutius, E., Burkhard Simma, Schreiber, S., Klopp, N., Schedel, Michaela, Depner, Martin, Laub, O., Liang, Liming, Stefan Schreiber, Illig, T., Rietschel, E., Michael Kabesch, Gut, Ivo Glynne, Mutius, Erika von, Frischer, T., Kabesch, Michael, Kabesch, M., Lathrop, Mark, Frischer, Thomas, Ashish Kumar, Jon Genuneit, Gut, Ivo G., Albrecht Bufe, Mark Lathrop, Kumar, A., Rietschel, Ernst, Ivo G. Gut, Illig, Thomas, Martin Depner, Liming Liang, Heinzmann, A., Andrea von Berg, Laub, Otto, Thomas Illig, Andreas Ruether, Simma, B., Vogelberg, Christian, Bufe, Albrecht, Erika von Mutius, Simma, Burkhard, Ivo G Gut, Kumar, Ashish, Sven Michel, Liang, L.M., Depner, M., Berg, Andrea von, Thomas Frischer, Michaela Schedel, Genuneit, J., Genuneit, Jon, Vogelberg, C., Norman Klopp, Klopp, Norman, Andrea Heinzmann, Liang Liming, Schedel Michaela, Schreiber Stefan, Ruether Andreas, Depner Martin, Kabesch Michael, Simma Burkhard, Gut Ivo G., Illig Thomas, von Berg Andrea, Kumar Ashish, Frischer Thomas, Laub Otto, Rietschel Ernst, Heinzmann Andrea, Klopp Norman, Michel Sven, Bufe Albrecht, von Mutius Erika, Genuneit Jon, Lathrop Mark, Vogelberg Christian +89 morecore +2 more sourcesComplete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons
bioRxiv, 2018 Autism Spectrum Disorder is phenotypically and genetically heterogeneous, but genomic analyses have identified candidate susceptibility genes. We present a CRISPR gene editing strategy to insert a protein tag and premature termination sites creating an ...E. Deneault, Sean H. White, D. C. Rodrigues, P. J. Ross, Muhammad Faheem, K. Zaslavsky, Zhuo-Zhi Wang, R. Alexandrova, G. Pellecchia, Wei Wei, A. Piekna, Gaganjot Kaur, J. Howe, Vickie Kwan, B. Thiruvahindrapuram, S. Walker, A. Lionel, P. Pasceri, D. Merico, Ryan K. C. Yuen, Karun K. Singh, J. Ellis, Stephen W. Scherer +22 moresemanticscholar +1 more sourceA genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease. [PDF]
, 2009 Kawasaki disease (KD) is a pediatric vasculitis that damages the coronary arteries in 25% of untreated and approximately 5% of treated children. Epidemiologic data suggest that KD is triggered by unidentified infection(s) in genetically susceptible ...Nievergelt, Caroline M., Sundel R.P., Li Y., Ng, S.B., Dillon, M, Shulman, ST, Sarah B Ng, Odam M., Nissan, M, Newburger, Jane W., Shimizu, C, Curtis, Nigel, Jane C Burns, Shike, Hiroko, Bonnard C., Burns, JC, Sundel, Robert P., Dillon, Michael, Bose, A, Kuijpers, Taco W., Burgner, D., Victoria J. Wright, Nissen, Michael, D., Burns Jane C., Shingadia D., Schork, NJ, Witt C., Kuijpers, Taco W, Wright, V.J., Kuipers, IM, Ling, L, Sarah B. Ng, Sonia Davila, Kuijpers, TW, Davila, S, Burgner, David, Ling, L., Odam, M., Breunis, W.B., Bonnard, C., Michie, C, Curtis, N, Ng S.B., Odam, Miranda, Burgner D., Hibberd, ML, Brogan P., Thalamuthu, A., Ziegler, J, Shah, Vanita, Shulman, Stanford T., Wright Victoria J., Ling L., Palasanthiran P., Rowley A.H., Ottenkamp, Jaap J., Breunis W.B., Shah V., Nissan, Michael, Filippini, L, Thalamuthu A., Carine Bonnard, Kuijpers T.W., Tulloh R., Christiansen F., Nourse C., Miranda Odam, Breunis, Willemijn B., Goldwater, P, Filippini L., Klein, Nigel, Biezeveld M., Mukasa, Thomas, Wright, Victoria J, Levin, Michael, Hibberd, M.L., Ng, SB, Curtis N., Thalamuthu, Anbupalam, Li Yi, Nissan M., Kuipers I.M., Rowley, AH, Kuijpers, T.W., Breunis, Willemijn B, Booy R., Dillon M., Rowley, Anne H., Kuipers, Irene M., Levin Michael, Davila, S., Davila Sonia, Booy, Robert, Schork N.J., Nourse, Clare, Li, Y, Shimizu, Chisato, Ng Sarah B., Tulloh, Robert, Consortium, IKDG, Goldwater, Paul, Nievergelt C.M., Bose A., Filippini, Luc, Christiansen, Frank, Li, Y., Ziegler, John, Shulman S.T., Bonnard, C, Geissler J., Burgner David, Willemijn B. Breunis, Ng, Sarah B., Breunis Willemijn B., Martin L Hibberd, Hibberd M.L., Palasanthiran, P, Ling, Ling, Witt, C, Christiansen, F, Breunis, WB, Burns J.C., Shah, V, Burns, Jane C., Hibberd, Martin L., Michie C., Burgner, D, Baker, Annette L., Ottenkamp, JJ, Taco W Kuijpers, Levin, M, Geissler, J, Mukasa, T, Shimizu C., Davila, Sonia, Bose, Anu, Levin, M., Bonnard Carine, Odam Miranda, Nievergelt, CM, Li, Yi, Brugner, David, Jane C. Burns, Davila S., Baker, AL, Ng, Sarah B, Newburger, JW, Baker A.L., Newburger J.W., Willemijn B Breunis, Shike, H, Burns, J.C., Michie, Colin, Biezeveld, Maarten, Hibberd, Martin L, Wright, Victoria J., Biezeveld, M, Levin M., Shingadia, D, Kuijpers Taco W., Martin L. Hibberd, Thalamuthu Anbupalam, Shike H., Wright, VJ, Shimizu Chisato, Ziegler J., Shingadia, Delane, Ottenkamp J.J., Yi Li, Klein N., Geissler, Judy, Burns, Jane C, International Kawasaki Disease Genetics Consortium, Palasanthiran, Pamela, Ling Ling, Taco W. Kuijpers, Wright V.J., Tulloh, R, Bonnard, Carine, Sundel, RP, Shimizu, C., Schork, Nicholas J., Goldwater P., Brogan, P, Mukasa T., Brogan, Paul, Hibberd Martin L., Victoria J Wright, Odam, M, Thalamuthu, A, Witt, Campbell, Michael Levin, David Burgner, Chisato Shimizu, Anbupalam Thalamuthu, Klein, N, Booy, R, Nourse, C +197 morecore +1 more sourceBone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims
Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran +21 morewiley +1 more sourceA Transcriptome‐Wide Association Study Identifies Candidate Susceptibility Loci and Genes for Lung Cancer Risk
Cancer MedicineBackground Genome‐wide association studies (GWAS) have identified over 80 susceptibility loci for lung cancer risk. However, the genes underlying these associations remain largely unknown. Methods We conducted a large transcriptome‐wide association study Tianying Zhao, Jiajun Shi, Yaohua Yang, Dan Zhou, Jie Ping, Shuai Xu, Lili Xu, Jie Wu, Xiao‐Ou Shu, Ran Tao, Bingshan Li, Wei Zheng, Jirong Long, Qiuyin Cai +13 moredoaj +1 more source
