Results 41 to 50 of about 583,132 (315)

Association study of candidate genes for susceptibility to Kashin-Beck disease in a Tibetan population [PDF]

, 2017
Background: Many osteoarthritis (OA) susceptibility genes have been identified in recent years. Given the overlap in the phenotype of joint inflammation between OA and Kashin-Beck disease (KBD), the aim of this study is to explore whether the reported OA
Yang, ZL (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Chengdu, Sichuan, Peoples R China., Liu, X, Ma, S, Yang, ZL (reprint author), Chinese Acad Sci, Sichuan Translat Med Res Hosp, Chengdu, Sichuan, Peoples R China., Lin, H, Yang, ZL (reprint author), Sichuan Prov Peoples Hosp, 32 First Ring Rd West 2, Chengdu 610072, Sichuan, Peoples R China., Yang, ZL (reprint author), Univ Elect Sci & Technol China, Sch Med, Chengdu, Sichuan, Peoples R China., Lu, F, Cheng, J, Tai, ZF, Li, YF, Yang, ZL (reprint author), Hosp Univ Elect Sci & Technol China, Ctr Human Mol Biol & Genet, 32 First Ring Rd West 2, Chengdu 610072, Sichuan, Peoples R China., Yang, ZL (reprint author), Hosp Univ Elect Sci & Technol China, Key Lab Human Dis Gene Study, Chengdu, Sichuan, Peoples R China., Huang, LL, Shi, Y, Yang, ZL   +15 more
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The role of vascular and hormonal genes in migraine susceptibility [PDF]

, 2006
Migraine is a primary headache disorder that involves both genetic and environmental components. Migraine is considered to be a polygenic disorder with a number of susceptibility genes having a minor but nonetheless significant impact on susceptibility ...
Griffiths, Lyn R, Quinlan, Sharon, Lea, Rodney, Colson, Natalie J., Griffiths, Lyn R., Lea, Rod A, Colson, Natalie, Griffiths, Lyn, Colson, Natalie J, Lea, Rod A.   +9 more
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HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure

Frontiers in Immunology, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19) was announced as an outbreak by the World Health Organization (WHO) in January 2020 and as a pandemic in March 2020.
Seik-Soon Khor, Yosuke Omae, Nao Nishida, Masaya Sugiyama, Noriko Kinoshita, Tetsuya Suzuki, Michiyo Suzuki, Satoshi Suzuki, Shinyu Izumi, Masayuki Hojo, Norio Ohmagari, Masashi Mizokami, Katsushi Tokunaga   +12 more
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PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background. [PDF]

, 2012
Genome-wide association studies identified PTPN2 (protein tyrosine phosphatase, non-receptor type 2) as susceptibility gene for inflammatory bowel diseases (IBD).
Darina Czamara, Seiderer, J., Ochsenkühn, Thomas, Nazanin Karbalai (177982), Beigel, F., Julia Seiderer (107820), Wagner, Johanna, Glas, J., Cornelia Tillack (174718), Friedrich, Matthias, Christian Steib (174731), Czamara, D., Jürgen Glas (107816), Tillack, Cornelia, Nazanin Karbalai, Stallhofer, Johannes, Torsten Olszak (107835), Brand, Stephan, Karbalai, N., Göke, B., Florian Beigel (174724), Thomas Ochsenkühn, Beigel, Florian, Matthias Friedrich (174721), Thomas Ochsenkühn (174734), Stallhofer, J., Ochsenkühn, T., Johannes Stallhofer, Matthias Friedrich, Wetzke, M., Darina Czamara (107824), Stephan Brand (107861), Cornelia Tillack, Julia Diegelmann, Steib, Christian, Göke, Burkhard, Wagner, J., Friedrich, M., Seiderer, Julia, Glas, Jürgen, Diegelmann, J., Burkhard Göke (109829), Martin Wetzke, Burkhard Göke, Christian Steib, Stephan Brand, Brand, S., Steib, C., Czamara, Darina, Martin Wetzke (107833), Julia Diegelmann (107830), Jürgen Glas, Johanna Wagner (174709), Johanna Wagner, Wetzke, Martin, Karbalai, Nazanin, Diegelmann, Julia, Johannes Stallhofer (174728), Torsten Olszak, Olszak, T., Florian Beigel, Julia Seiderer, Olszak, Torsten, Tillack, C.   +63 more
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Turning Susceptibility into Strength: A New Era of Durable Resistance in Plants Through Genome Editing

Plants
In plants, resistance genes (R) are key players in combatting diseases caused by various phytopathogens. Typically, resistance relies on detecting a single pathogen-derived molecular pattern.
Shallu Thakur, Simranjot Kaur, Sudeep Adhikari, Prerna Sabharwal, Yuqing Fu, Geoffrey Meru   +5 more
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Association between 15 known or potential breast cancer susceptibility genes and breast cancer risks in Chinese women

Cancer Biology & Medicine, 2022
Objective: There are many hereditary breast cancer patients in China, and multigene panel testing has been a new paradigm of genetic testing for these patients and their relatives.
Fenfen Fu, Dongjie Zhang, Li Hu, Senthil Sundaram, Dingge Ying, Ying Zhang, Shuna Fu, Juan Zhang, Lu Yao, Ye Xu, Yuntao Xie   +10 more
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Unifying candidate gene and GWAS Approaches in Asthma. [PDF]

, 2010
The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS ...
Heinzmann, Andrea, Ruether, Andreas, Otto Laub, Bufe, A., Lathrop, M, Schedel, M., Michel, Sven, Ruether, A., Michel, S., Schreiber, Stefan, von Berg, A., Gut, I.G., Christian Vogelberg, Ernst Rietschel, von Mutius, E., Burkhard Simma, Schreiber, S., Klopp, N., Schedel, Michaela, Depner, Martin, Laub, O., Liang, Liming, Stefan Schreiber, Illig, T., Rietschel, E., Michael Kabesch, Gut, Ivo Glynne, Mutius, Erika von, Frischer, T., Kabesch, Michael, Kabesch, M., Lathrop, Mark, Frischer, Thomas, Ashish Kumar, Jon Genuneit, Gut, Ivo G., Albrecht Bufe, Mark Lathrop, Kumar, A., Rietschel, Ernst, Ivo G. Gut, Illig, Thomas, Martin Depner, Liming Liang, Heinzmann, A., Andrea von Berg, Laub, Otto, Thomas Illig, Andreas Ruether, Simma, B., Vogelberg, Christian, Bufe, Albrecht, Erika von Mutius, Simma, Burkhard, Ivo G Gut, Kumar, Ashish, Sven Michel, Liang, L.M., Depner, M., Berg, Andrea von, Thomas Frischer, Michaela Schedel, Genuneit, J., Genuneit, Jon, Vogelberg, C., Norman Klopp, Klopp, Norman, Andrea Heinzmann   +67 more
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TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres. [PDF]

, 2011
Shorter telomeres have been associated with increased risk of malignancy, including colorectal cancer (CRC). Telomere length is heritable and may be an intermediate phenotype linked to genetic susceptibility to ...
Tomlinson, IP, A M Jones, Beggs, A. D., Jones, A. M., M Walker, Jones, A.M., Dunlop, MG, Beggs, A.D., Tenesa, A., A D Beggs, Kerr, D, A Zauber, A Tenesa, Hodgson, S. V., Walker, M., M Bertagnolli, R Midgley, Carvajal-Carmona, L, Dunlop, Malcolm, Tenesa, Albert, Tenesa, A, Kerr, D., Jones, AM, Beggs, AD, M G Dunlop, Kerr, David, Jones, A M, Tomlinson, IPM, Carvajal-Carmona, L., Campbell, H.; id_orcid, Tomlinson, I P M, S Ballereau, Tomlinson, I. P. M., Zauber, A., S V Hodgson, Campbell, H, H Campbell, Farrington, S., Hodgson, SV, Ballereau, S., Campbell, H., Midgley, Rachel, Walker, M, S Farrington, I P M Tomlinson, Dunlop, M G, K Howarth, Farrington, S.; id_orcid, Howarth, K., Ballereau, S, Hodgson, S.V., Bertagnolli, M., Tomlinson, I.P., Beggs, A D; id_orcid, Midgley, R., D Kerr, Bertagnolli, M, L Carvajal-Carmona, Hodgson, S V, Dunlop, M. G., Midgley, R, Zauber, A, Howarth, K, Farrington, S   +63 more
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Identification of Susceptibility Genes in Castanea sativa and Their Transcription Dynamics following Pathogen Infection

Plants, 2021
Castanea sativa is one of the main multipurpose tree species valued for its timber and nuts. This species is susceptible to two major diseases, ink disease and chestnut blight, caused by Phytophthora spp. and Cryphonectria parasitica, respectively.
Vera Pavese, Andrea Moglia, Paolo Gonthier, Daniela Torello Marinoni, Emile Cavalet-Giorsa, Roberto Botta   +5 more
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Tumor Susceptibility Genes

Cancer Control, 1998
Cancer develops and progresses as the result of accumulated genetic damage or mutations. These mutations are most commonly described as either oncogenes, which positively regulate cell growth, or tumor suppressor genes, which negatively regulate cell growth.
openaire   +2 more sources