Results 21 to 30 of about 545,336 (266)

Influence of Nitrogen on Grapevine Susceptibility to Downy Mildew

Plants, 2023
Downy mildew, caused by the obligate parasite Plasmopara viticola, is one of the most important threats to viticulture. The exploitation of resistant and susceptibility traits of grapevine is one of the most promising ways to increase the sustainability ...
Demetrio Marcianò, Valentina Ricciardi, Giuliana Maddalena, Annamaria Massafra, Elena Marone Fassolo, Simona Masiero, Piero Attilio Bianco, Osvaldo Failla, Gabriella De Lorenzis, Silvia Laura Toffolatti   +9 more
doaj   +1 more source

Exploring New Routes for Genetic Resistances to Potyviruses: The Case of the Arabidopsis thaliana Phosphoglycerates Kinases (PGK) Metabolic Enzymes

Viruses, 2022
The development of recessive resistance by loss of susceptibility is a consistent strategy to combat and limit damages caused by plant viruses. Susceptibility genes can be turned into resistances, a feat that can either be selected among the plant’s ...
Mamoudou Diop, Jean-Luc Gallois
doaj   +1 more source

Inactivation of tomato WAT1 leads to reduced susceptibility to Clavibacter michiganensis through downregulation of bacterial virulence factors

Frontiers in Plant Science, 2023
Tomato bacterial canker caused by Clavibacter michiganensis (Cm) is considered to be one of the most destructive bacterial diseases of tomato. To date, no resistance to the pathogen has been identified. While several molecular studies have identified (Cm)
Eleni Koseoglou, Eleni Koseoglou, Katharina Hanika, Mas M. Mohd Nadzir, Wouter Kohlen, Jan M. van der Wolf, Richard G. F. Visser, Yuling Bai   +7 more
doaj   +1 more source

Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4+ T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome

Frontiers in Immunology, 2021
ObjectivePrimary Sjögren’s syndrome (pSS) is a systemic autoimmune disease, and its pathogenetic mechanism is far from being understood. In this study, we aimed to explore the cellular and molecular mechanisms that lead to pathogenesis of this disease ...
Xiaoping Hong, Xiaoping Hong, Shuhui Meng, Donge Tang, Tingting Wang, Liping Ding, Haiyan Yu, Heng Li, Dongzhou Liu, Yong Dai, Min Yang   +10 more
doaj   +1 more source

Family history of any cancer for childhood leukemia patients in Sweden

eJHaem, 2021
Acute lymphoblastic leukemia (ALL) is the most common childhood leukemia, while the other types, acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML) are much rarer.
Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki   +4 more
doaj   +1 more source

The genetic basis of onset age in schizophrenia: evidence and models

Frontiers in Genetics, 2023
Schizophrenia is a heritable neurocognitive disorder affecting about 1% of the population, and usually has an onset age at around 21–25 in males and 25–30 in females.
Na Zhan, Pak C. Sham, Pak C. Sham, Pak C. Sham, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Hon-Cheong So, Simon S. Y. Lui   +11 more
doaj   +1 more source

Mutation Frequency in Main Susceptibility Genes Among Patients With Head and Neck Paragangliomas

Frontiers in Genetics, 2020
Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors that have a high degree of heritability and are predominantly associated with mutations in ten genes, such as SDHx, SDHAF2, VHL, RET, NF1, TMEM127, MAX, FH, MEN2, and SLC25A11 ...
Anastasiya V. Snezhkina, Maria S. Fedorova, Vladislav S. Pavlov, Dmitry V. Kalinin, Alexander L. Golovyuk, Elena A. Pudova, Zulfiya G. Guvatova, Nataliya V. Melnikova, Alexey A. Dmitriev, George S. Razmakhaev, Andrey A. Poloznikov, Galina S. Alekseeva, Andrey D. Kaprin, George S. Krasnov, Anna V. Kudryavtseva   +14 more
doaj   +1 more source

Exploration of Lung Cancer-Related Genetic Factors via Mendelian Randomization Method Based on Genomic and Transcriptomic Summarized Data

Frontiers in Cell and Developmental Biology, 2021
Lung carcinoma is one of the most deadly malignant tumors in mankind. With the rising incidence of lung cancer, searching for the high effective cures become more and more imperative.
Nitao Cheng, Xinran Cui, Chen Chen, Changsheng Li, Jingyu Huang   +4 more
doaj   +1 more source

HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure

Frontiers in Immunology, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19) was announced as an outbreak by the World Health Organization (WHO) in January 2020 and as a pandemic in March 2020.
Seik-Soon Khor, Yosuke Omae, Nao Nishida, Masaya Sugiyama, Noriko Kinoshita, Tetsuya Suzuki, Michiyo Suzuki, Satoshi Suzuki, Shinyu Izumi, Masayuki Hojo, Norio Ohmagari, Masashi Mizokami, Katsushi Tokunaga   +12 more
doaj   +1 more source

Turning Susceptibility into Strength: A New Era of Durable Resistance in Plants Through Genome Editing

Plants
In plants, resistance genes (R) are key players in combatting diseases caused by various phytopathogens. Typically, resistance relies on detecting a single pathogen-derived molecular pattern.
Shallu Thakur, Simranjot Kaur, Sudeep Adhikari, Prerna Sabharwal, Yuqing Fu, Geoffrey Meru   +5 more
doaj   +1 more source