Results 21 to 30 of about 9,010,468 (307)
Frontiers in Endocrinology, 2022 Thyroid cancer is the malignant tumor that is increasing most rapidly in the world, mainly at the expense of sporadic papillary thyroid carcinoma. The somatic alterations involved in the pathogenesis of sporadic follicular cell derived tumors are well ...
María Sánchez-Ares +9 more
doaj +1 more source
Stop helping pathogens: engineering plant susceptibility genes for durable resistance
Current Opinion in Biotechnology, 2021 Alternatives to protect crops against diseases are desperately needed to secure world food production and make agriculture more sustainable. Genetic resistance to pathogens utilized so far is mostly based on single dominant resistance genes that mediate ...
H. García-Ruíz +2 more
semanticscholar +1 more source
Transcription activator-like effectors (TALEs) role in plant response to Xanthomonas [PDF]
مجله بیوتکنولوژی کشاورزی, 2018 Xanthomonas is an important plant pathogenic bacteria and cause economic losses in a wide range of crop plants. The type III secretion system as a crucial pathogenicity factor is used to inject effector proteins into the host cell.
Masood Shamsbakhsh +2 more
doaj +1 more source
Frontiers in Plant Science, 2021 Cannabis sativa is increasingly being grown around the world for medicinal, industrial, and recreational purposes. As in all cultivated plants, cannabis is exposed to a wide range of pathogens, including powdery mildew (PM).
Noémi Pépin +3 more
doaj +1 more source
Enhancer release and retargeting activates disease-susceptibility genes
Nature, 2021 The functional engagement between an enhancer and its target promoter ensures precise gene transcription1. Understanding the basis of promoter choice by enhancers has important implications for health and disease. Here we report that functional loss of a
Soohwan Oh +16 more
semanticscholar +1 more source
Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models [PDF]
Intestinal Research, 2020 The specific pathogenesis underlining inflammatory bowel disease (IBD) is very complicated, and it is further more difficult to clearly explain the pathophysiology of 2 major forms of IBD, Crohn’s disease (CD) and ulcerative colitis (UC), and both ...
Emiko Mizoguchi +3 more
doaj +1 more source
Susceptibility reversed: modified plant susceptibility genes for resistance to bacteria.
Trends in Plant Science, 2021 Plants have evolved complex defence mechanisms to avoid invasion of potential pathogens. Despite this, adapted pathogens deploy effector proteins to manipulate host susceptibility (S) genes, rendering plant defences ineffective.
Eleni Koseoglou +3 more
semanticscholar +1 more source
Type 1 Diabetes and Autoimmune Thyroid Disease—The Genetic Link
Frontiers in Endocrinology, 2021 Type 1 diabetes (T1D) and autoimmune thyroid disease (AITD) are the most frequent chronic autoimmune diseases worldwide. Several autoimmune endocrine and non-endocrine disorders tend to occur together.
Lara Frommer, George J. Kahaly
doaj +1 more source
Epigenetics of functional hypothalamic amenorrhea
Frontiers in Endocrinology, 2022 Functional hypothalamic amenorrhea (FHA) is a temporary infertility characterized by the suppression of the hypothalamic–pituitary–gonadal (HPG) axis, induced by the inhibition of the hypothalamic pulsatile secretion of the gonadotropin-releasing hormone
L. Fontana +8 more
doaj +1 more source
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]
, 2010 Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
S Eyre +21 more
core +2 more sources