Results 1 to 10 of about 583,132 (315)
Deciphering the immunocellular regulatory network in inflammatory bowel disease: from susceptibility genes to cellular effectors and toward precision therapies [PDF]
Frontiers in ImmunologyInflammatory bowel disease (IBD) is a chronic, immune-mediated intestinal disorder driven by dysregulated immune responses in genetically susceptible individuals.
Zhuzhu Wu +12 more
doaj +2 more sources
Bone & Joint Research, 2023 AimsDegenerative cervical spondylosis (DCS) is a common musculoskeletal disease that encompasses a wide range of progressive degenerative changes and affects all components of the cervical spine.
Jiawen Xu +7 more
doaj +3 more sources
Bioinformatic analysis of biological pathways in coronary heart disease and Alzheimer’s disease
Бюллетень сибирской медицины, 2023 Aim. Using bioinformatic tools, to perform a pathway enrichment analysis in Alzheimer’s disease and coronary heart disease (CHD).Materials and methods.
N. Y. Chasovskikh, E. E. Chizhik
doaj +1 more source
Frontiers in Endocrinology, 2022 Thyroid cancer is the malignant tumor that is increasing most rapidly in the world, mainly at the expense of sporadic papillary thyroid carcinoma. The somatic alterations involved in the pathogenesis of sporadic follicular cell derived tumors are well ...
María Sánchez-Ares +9 more
doaj +1 more source
Transcription activator-like effectors (TALEs) role in plant response to Xanthomonas [PDF]
مجله بیوتکنولوژی کشاورزی, 2018 Xanthomonas is an important plant pathogenic bacteria and cause economic losses in a wide range of crop plants. The type III secretion system as a crucial pathogenicity factor is used to inject effector proteins into the host cell.
Masood Shamsbakhsh +2 more
doaj +1 more source
Frontiers in Plant Science, 2021 Cannabis sativa is increasingly being grown around the world for medicinal, industrial, and recreational purposes. As in all cultivated plants, cannabis is exposed to a wide range of pathogens, including powdery mildew (PM).
Noémi Pépin +3 more
doaj +1 more source
Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models [PDF]
Intestinal Research, 2020 The specific pathogenesis underlining inflammatory bowel disease (IBD) is very complicated, and it is further more difficult to clearly explain the pathophysiology of 2 major forms of IBD, Crohn’s disease (CD) and ulcerative colitis (UC), and both ...
Emiko Mizoguchi +3 more
doaj +1 more source
Type 1 Diabetes and Autoimmune Thyroid Disease—The Genetic Link
Frontiers in Endocrinology, 2021 Type 1 diabetes (T1D) and autoimmune thyroid disease (AITD) are the most frequent chronic autoimmune diseases worldwide. Several autoimmune endocrine and non-endocrine disorders tend to occur together.
Lara Frommer, George J. Kahaly
doaj +1 more source
Epigenetics of functional hypothalamic amenorrhea
Frontiers in Endocrinology, 2022 Functional hypothalamic amenorrhea (FHA) is a temporary infertility characterized by the suppression of the hypothalamic–pituitary–gonadal (HPG) axis, induced by the inhibition of the hypothalamic pulsatile secretion of the gonadotropin-releasing hormone
L. Fontana +8 more
doaj +1 more source
Frontiers in Plant Science, 2022 Different genome editing approaches have been used to engineer resistance against plant viruses. The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas; CRISPR/Cas) systems to create pinpoint genetic ...
Fredy D. A. Silva +1 more
doaj +1 more source