Results 11 to 20 of about 545,336 (266)

Genomic Analysis Highlights Putative Defective Susceptibility Genes in Tomato Germplasm

open access: yesPlants, 2023
Tomato (Solanum lycopersicum L.) is one of the most widely grown vegetables in the world and is impacted by many diseases which cause yield reduction or even crop failure.
Ruiling Li   +5 more
doaj   +1 more source

Improving Pathogen Resistance by Exploiting Plant Susceptibility Genes in Coffee (Coffea spp.)

open access: yesAgronomy, 2020
Coffee (Coffea spp.) is an economically important crop widely cultivated in (sub) tropical countries worldwide. Commercial coffee production relies mainly on two related species, namely C. arabica and C. canephora.
Lei Cui   +3 more
doaj   +1 more source

Susceptibility Is New Resistance: Wheat Susceptibility Genes and Exploitation in Resistance Breeding

open access: yesAgriculture, 2022
Adapted pathogens and pests seriously threaten global wheat production. During pathogen and pest infections, wheat susceptibility (S) genes are exploited to support the compatibility of wheat with pathogens and pests.
Mengmeng Li, Zige Yang, Cheng Chang
doaj   +1 more source

A gene for susceptibility to tuberculosis [PDF]

open access: yesCanadian Medical Association Journal, 2005
The complex genetic nature of what makes some people more susceptible than others to tuberculosis (TB) may finally be revealing itself. The answer may lie in the genes that control cell-mediated immunity specifically a newly discovered gene that governs how macrophages cope with infectious organisms such as Mycobacterium tuberculosis.
openaire   +2 more sources

Gene–gene interactions in breast cancer susceptibility [PDF]

open access: yesHuman Molecular Genetics, 2011
There have been few definitive examples of gene-gene interactions in humans. Through mutational analyses in 7325 individuals, we report four interactions (defined as departures from a multiplicative model) between mutations in the breast cancer susceptibility genes ATM and CHEK2 with BRCA1 and BRCA2 (case-only interaction between ATM and BRCA1/BRCA2 ...
Turnbull C   +39 more
openaire   +7 more sources

Genetic Susceptibility of the Host in Virus-Induced Diabetes

open access: yesMicroorganisms, 2020
Enteroviruses, especially Coxsackie B viruses, are among the candidate environmental factors causative of type 1 diabetes. Host genetic factors have an impact on the development of virus-induced diabetes (VID).
Keiichiro Mine   +5 more
doaj   +1 more source

Transcriptome-Wide Association Studies and Integration Analysis of mRNA Expression Profiles Identify Candidate Genes and Pathways Associated With Ankylosing Spondylitis

open access: yesFrontiers in Immunology, 2022
This study aimed to identify susceptibility genes and pathways associated with ankylosing spondylitis (AS) by integrating whole transcriptome-wide association study (TWAS) analysis and mRNA expression profiling data.
Ruoyang Feng   +4 more
doaj   +1 more source

Susceptibility genes for complex epilepsy [PDF]

open access: yesHuman Molecular Genetics, 2005
Common idiopathic epilepsies are, clinically and genetically, a heterogeneous group of complex seizure disorders. Seizures arise from periodic neuronal hyperexcitability of unknown cause. The genetic component is mostly polygenic, where each susceptibility gene in any given individual is likely to represent a small component of the total heritability ...
Mulley, J.   +4 more
openaire   +3 more sources

Is COMT a Susceptibility Gene for Schizophrenia? [PDF]

open access: yesSchizophrenia Bulletin, 2007
Catechol-O-methyl transferase (COMT) is a catabolic enzyme involved in the degradation of a number of bioactive molecules; of principal interest to psychiatry, these include dopamine. The enzyme is encoded by the COMT gene. COMT is located (along with 47 other genes) in a fragment of chromosome 22q11 which when deleted results in a complex syndrome ...
Hywel J, Williams   +2 more
openaire   +2 more sources

Mining Grapevine Downy Mildew Susceptibility Genes: A Resource for Genomics-Based Breeding and Tailored Gene Editing

open access: yesBiomolecules, 2021
Several pathogens continuously threaten viticulture worldwide. Until now, the investigation on resistance loci has been the main trend to understand the interaction between grapevine and the mildew causal agents.
Carlotta Pirrello   +5 more
doaj   +1 more source

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