Results 51 to 60 of about 583,132 (315)

Plant Disease Susceptibility Genes? [PDF]

open access: yesThe Plant Cell, 2002
A recent search of the ISI Web of Science identified 524 documents related to “plant disease resistance” and just 1 match for the phrase “plant disease susceptibility.” This does not mean that scientists are not engaged in the study of what makes plants susceptible to disease.
openaire   +2 more sources

Identifying Autism Susceptibility Genes [PDF]

open access: yesNeuron, 2000
Recent molecular genetic studies indicate that the goal of identifying autism susceptibility genes may soon be attainable. Taken together, the linkage findings suggest that there is a high probability that a region on chromosome 7q contains a susceptibility locus for autism. Nevertheless, the isolation of a putative gene in this region still represents
Maestrini, E   +3 more
openaire   +3 more sources

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. [PDF]

open access: yes, 2007
The IL23R gene has been identified as a susceptibility gene for inflammatory bowel disease (IBD) in the North American population. The aim of our study was to test this association in a large German IBD cohort and to elucidate potential interactions with
Folwaczny, Christian   +70 more
core   +1 more source

Research Progress on Genetic Susceptibility to Triple-Negative Breast Cancer

open access: yesZhongliu Fangzhi Yanjiu, 2023
Triple-negative breast cancer (TNBC) is a type of breast cancer that is difficult to treat, has a poor prognosis, and is prone to recurrence and metastasis in the early postoperative period.
ZHANG Lijia   +5 more
doaj   +1 more source

Cardiometabolic traits mediating the effect of education on the risk of DKD and CKD: a Mendelian randomization study

open access: yesFrontiers in Nutrition
BackgroundBoth diabetic kidney disease (DKD) and chronic kidney disease (CKD) are more prevalent among individuals with lower levels of education in observational studies.
Yukai Wang   +4 more
doaj   +1 more source

Associations of genetic variants contributing to gut microbiota composition in diabetic nephropathy

open access: yesFrontiers in Endocrinology, 2023
IntroductionThe gut microbiota is strongly associated with multiple kidney diseases, and since microbial composition is heritable, we hypothesized that genetic variations controlling gut microbiota composition were associated with diabetic nephropathy ...
Xiao Lu   +4 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

New susceptibility Loci associated with kidney disease in type 1 diabetes [PDF]

open access: yes, 2012
Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation.
Benjamin J. Keller (135013)   +587 more
core   +1 more source

Eukaryotic translation initiation factor 4E family member nCBP facilitates the accumulation of TGB-encoding viruses by recognizing the viral coat protein in potato and tobacco

open access: yesFrontiers in Plant Science, 2022
Due to their limited coding capacity, plant viruses have to depend on various host factors for successful infection of the host. Loss of function of these host factors will result in recessively inherited resistance, and therefore, these host factors are
Ruhao Chen   +9 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

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