Results 131 to 140 of about 503,154 (248)

Integrating gene expression with summary association statistics to identify susceptibility genes for 30 complex traits [PDF]

, 2016
Nicholas Mancuso, Huwenbo Shi, Pagé C. Goddard, Gleb Kichaev, Alexander Gusev, Bogdan Paşaniuc   +5 more
openalex   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Harnessing inherent immune defenses of crops for sustainable pest management

Frontiers in Science
Jyoti Shah, Jyoti Shah
doaj   +1 more source

Confirmation of BIK and SAMHD1 as Prostate Cancer Susceptibility Genes. [PDF]

Prostate
Pavlovich CP, Wei J, Gielzak M, Shi Z, Tran H, Ashworth A, Lilly Zheng S, Walsh PC, Luo J, Helfand BT, Isaacs WB, Xu J.   +11 more
europepmc   +1 more source

Prevalence, antibiotic susceptibility and characterization of antibiotic resistant genes among carbapenem-resistant Gram-negative bacilli and yeast in intestinal flora of cancer patients in North Lebanon

, 2017
Rima Christophy, Marwan Osman, Hassan Mallat, Marcel Achkar, Azzam Ziedeh, Walid Moukaddem, Fouad Dabboussi, Monzer Hamzé   +7 more
openalex   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Cross-tissue transcriptome-wide association studies identify genetic susceptibility genes for prostate cancer. [PDF]

BMC Cancer
Hua J, Qian Y, Lu Y, Zhang Q, Que H, Zeng T, Li Q, Deng J, Xie J.   +8 more
europepmc   +1 more source

Impact of DNA repair gene variants on male infertility susceptibility in south Indian population

M. Venkateswara Rao, K. V. N. Geetha Devi, D. Rajarajeswari, K. Ashalatha   +3 more
openalex   +2 more sources

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Priming defense by transiently suppressing plant susceptibility genes in ornamental crops: A novel strategy for post-harvest diseases management

Frontiers in Plant Science, 2022
Xintong Liu, Yuling Bai, Zhao Zhang, Zhao Zhang   +3 more
doaj   +1 more source