Results 71 to 80 of about 371,729 (309)

Improvement of the ergonomical structure of Knapsack sprayer to propel cart sprayer (PCS) [PDF]

, 2020
A sprayer is a device used to spray a liquid projection mostly used in agriculture crop used to apply such as pesticides. The sprayer’s usage are based on the type of the background of the farmers scale in agriculture. Large scale of farmers will use the
Ahamad Azahari, Ahmad Syakir, Kamaruddin, Muhammad Amar, Muslim, Maizatul Anis, Nordin, Norbaizura   +3 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Validation of transport and friction formulae for upper plane bed by experiments in rectangular pipe

Journal of Hydrology and Hydromechanics, 2013
The paper describes results of validation of authors' recently proposed formulae for sediment transport and bed friction in the upper plane bed regime using laboratory experiments in a pressurized pipe.
Matoušek Václav, Krupička Jan, Picek Tomáš   +2 more
doaj   +1 more source

Estimation of Suspended Sediment Loads Using Copula Functions [PDF]

Water, 2017
Suspended sediment load (SSL) observations are usually less frequent than precipitation and river discharge measurements; therefore a reliable procedure is needed for the estimation of SSL. One year of precipitation, SSL, and discharge measurements at 20-min intervals were performed at the Kuzlovec torrent in Slovenia.
Nejc Bezak, Simon Rusjan, Marjeta Kramar Fijavž, Matjaž Mikoš, Mojca Šraj   +4 more
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Quantifying temporal and spatial variations in sediment, nitrogen and phosphorus transport in stream inflows to a large eutrophic lake [PDF]

, 2013
High-frequency sampling of two major stream inflows to a large eutrophic lake (Lake Rotorua, New Zealand) was conducted to measure inputs of total suspended sediment (TSS), and fractions of nitrogen and phosphorus (P).
Abell, Jonathan Michael, Hamilton, David P., Rutherford, J. C.   +2 more
core   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

A Generalized Mathematical Model for the Fracture Problem of the Suspended Highway

MATEC Web of Conferences, 2017
In order to answer dangling fracture problems of highway, the suspended pavement equivalent for non - suspended pavement, through the special boundary conditions has been suspended highway stress field of expression, in accordance with the 3D fracture ...
Zhao Ying, Lu Ming
doaj   +1 more source