Results 51 to 60 of about 371,729 (309)

Seasonal and Spatial Characteristics of Suspended Sediment Load and their Controlling Factors in the Upper Indus River Basin, Pakistan

open access: yesPakistan Journal of Analytical & Environmental Chemistry, 2023
Understanding the seasonal and spatial characteristics of suspended sediment load is extremely important for efficient water resource management. The characteristics of suspended sediment load reflect the soil erosion, transport and deposition. The upper
Muhammad Dodo Jagirani   +8 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

An Improved Method for Swing State Estimation in Multirotor Slung Load Applications

open access: yesDrones, 2023
A method is proposed to estimate the swing state of a suspended payload in multirotor drone delivery scenarios. Starting from the equations of motion of the coupled slung load system, defined by two point masses interconnected by a rigid link, a ...
Emanuele Luigi de Angelis   +1 more
doaj   +1 more source

Nitrogen, Phosphorus, and Suspended Solids Concentrations in Tributaries to the Great Bay Estuary Watershed in 2010 [PDF]

open access: yes, 2011
Nitrogen, phosphorus, and sediment loads to the Great Bay Estuary are a growing concern. The Piscataqua Region Estuaries Partnership (PREP) calculates the nitrogen load from tributaries to the Great Bay Estuary for its State of the Estuaries reports ...
New Hampshire Department of Environmental Services   +2 more
core   +5 more sources

Fluvial transport of suspended sediment and organic carbon during flood events in a large agricultural catchment in southwest France. [PDF]

open access: yes, 2011
Water draining from a large agricultural catchment of 1 110 km2 in southwest France was sampled over an 18-month period to determine the temporal variability in suspended sediment (SS) and dissolved (DOC) and particulate organic carbon (POC) transport ...
Aitkenhead   +60 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Development of a 6-DOF Testing Platform for Multirotor Flying Vehicles with Suspended Loads

open access: yesAerospace, 2021
The development of multirotor vehicles can often be a dangerous and costly undertaking due to the possibility of crashes resulting from faulty controllers.
Saad M. S. Mukras, Hanafy M. Omar
doaj   +1 more source

Variability of the chemical index of alteration (CIA) in the Paraná River suspended load [PDF]

open access: yes, 1998
Variability of the chemical index of alteration (CIA) in the Paraná River suspended ...
Depetris, Pedro J., Probst, Jean-Luc
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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