Results 41 to 50 of about 1,456,571 (303)
A novel framework for turbidity source apportionment of the urban lakeside river network
Ecological Indicators, 2023 Turbidity source apportionment is essential but complex for precise environmental rehabilitation of worldwide urban lakeside river networks impaired by turbidity.
Renhua Yan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The effect of suspended sentences on imprisonment [PDF]
, 2014 This study finds that although suspended sentences were introduced as an alternative to prison, in New South Wales they appear to have had the opposite effect.
Don Weatherburn, Patricia Menendez
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Geochemistry, Geophysics, Geosystems, 2007 The explosive eruption of voluminous silicic magmas often produces widespread and massive deposits formed from pyroclastic density currents. While these punctuated events dramatically alter the landscape and have potential climate‐altering impact, our ...
Josef Dufek, George W. Bergantz
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
ASSESSING SUSPENDED SEDIMENT YIELD IN THE SAF SAF GAUGED CATCHMENT, NORTHEASTERN ALGERIA [PDF]
Malaysian Journal of Geosciences, 2019 Many studies on sediment transport have been carried out on Algerian rivers but few studies have been undertaken in catchments of the Northeast of Algeria. The scarcity or discontinuity on sediment transport measurements reduces knowledge about soil loss.
K. Khanchoul, Z.A. Boukhrissa
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Monitoring the fluvial palynomorph load in a lowland temperate catchment and its relationship to suspended sediment and discharge [PDF]
, 2008 Despite it being a component of the seston we know very little about fluvial (waterborne) pollen and spore (palynomorph) transport. This paper presents the results of a monitoring programme conducted over two years and at a catchment scale in South West ...
Walling, D.E. +2 more
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Dynamics of fluvial fine sediment transfer in the River Esk, North Yorkshire, UK [PDF]
, 2006 A full understanding of the complexities of fluvial suspended sediment dynamics requires a holistic approach. The study presented here addresses fine sediment transfer in the River Esk catchment, which is suffering from the adverse effects of increased ...
Mills, Carolyn
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