Results 91 to 100 of about 7,608 (271)

[Evaluation of two phenotypic techniques and a commercial multiplex molecular panel for the detection of different carbapenemases]. [PDF]

Rev Esp Quimioter, 2023
Hernando Parreño N, Sampere Martínez A.   +1 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

[Management of immunosuppressive therapy in kidney transplant recipients with COVID19. A multicentre national study derived form the S.E.N. COVID registry.] [PDF]

Nefrologia, 2022
López-Oliva MO, Pérez-Flores I, Molina M, José Aladrén M, Trujillo H, Redondo-Pachón D, López V, Facundo C, Villanego F, Rodríguez M, Carmen Ruiz M, Antón P, Rivas-Oural A, Cabello S, Portolés J, de la Vara L, Tabernero G, Valero R, Galeano C, Moral E, Ventura A, Coca A, Muñoz MÁ, Hernández-Gallego R, Shabaka A, Ledesma G, Martínez P, Ángeles Rodríguez M, Tamajón LP, Cruzado L, Emilio Sánchez J, Jiménez C.   +31 more
europepmc   +1 more source

Estudio de conservantes para suspensiones de nitrofurantoína

, 2023
Con objeto de establecer una protección adecuada para Nitrofurantoína, se estudia, en una de sus formas farmacéuticas -las suspensiones-, la influencia que ejercen varios conservantes de acción muy diferente. Se analizan los resultados correspondientes mediante observación visual, determinación del pH, del punto de fusión y de los espectros ...
Ruiz Martínez, M.ª A., Gallardo Lara, Visitación, Parera Vialard, Antonio, Delgado Mora, Ángel Vicente   +3 more
openaire   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Estudio reológico de suspensiones de carboximetilcelulosa en presencia de nanomateriales

, 2018
En el presente trabajo se ha realizado un estudio del comportamiento reológico de suspensiones acuosas de Carboximetilcelulosa (CMC) con diferentes nanomateriales: Nanosílica (NS), Nanoarcilla (NC) y Óxido de Grafeno Expandido (EGO).
Díaz-Alejo, Alberto, Cerpa Naranjo, Arisbel, Valverde Palomino, José Luis, Rodríguez Mayor, María Lourdes   +3 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Estudio del cortocircuito de finos en hidrociclones operados con suspensiones poliminerales en la industria cementera Lina María Chica Osorio.

, 2009
Se presentan los resultados obtenidos a partir de un trabajo de investigación experimental, para determinar las principales variables operacionales que están asociadas al cortocircuito de finos y al fenómeno de “fish hook” en hidrociclones de 10 pulgadas
Chica Osorio, Lina María
core  

Mixed oral candidiasis in type 2 diabetic patients: Identification and spectrum of sensitivity [PDF]

Biomedica, 2023
Araiza J, Sánchez-Pedraza V, Carrillo AK, Fernández-Samar D, Tejeda J, Bonifaz A.   +5 more
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source