[Management of immunosuppressive therapy in kidney transplant recipients with COVID19. A multicentre national study derived form the S.E.N. COVID registry.] [PDF]
Nefrologia, 2022 López-Oliva MO +31 more
europepmc +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
A sequential procedure for the quantification of biologically produced polyphosphate in sediment samples [PDF]
, 2011 Polyphosphate (poly-P) is a phosphate storage compound widespread in prokaryotic and eukaryotic cells. Its quantification, however, is not yet well developed for sediment samples because of the difficulties associated with using a single extractant to ...
Golterman, Han L. +2 more
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Mixed oral candidiasis in type 2 diabetic patients: Identification and spectrum of sensitivity [PDF]
Biomedica, 2023 Araiza J +5 more
europepmc +1 more source
Study of the antioxidant capacity of the extracellular medium of suspensions elicited with an extract of Moringa oleifera leaves [PDF]
, 2018 [Resumo]: Moringa oleifera é unha árbore que destaca polas súas múltiples propiedades nutritivas e farmacolóxicas. Unha das propiedades que posúe Moringa é a cantidade de fenoles que contén e que lle aporta unha gran capacidade para sobrevivir en ...
Fernández Vázquez, Mª Ángeles
core
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
[Prevalence of dental and mucosal lesions among the pediatric population who attended the emergency department of a general hospital]. [PDF]
An Sist Sanit Navar, 2023 Suárez Ardura M +2 more
europepmc +1 more source
Efecto de las características del biorreactor y de su manejo sobre el desarrollo de cultivos embriogénicos de alcornoque [PDF]
, 2009 En el marco del proyecto SEFEAL-2, liderado por TRAGSA, se aplican protocolos de embriogénesis somática (ES) para desarrollar variedades de alcornoque de alta calidad y productividad. Al mismo tiempo se mejora la técnica de ES para abaratar los costes y
Alonso Blázquez, N. +7 more
core
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source