Results 81 to 90 of about 1,389,993 (326)

Sustainable product development strategies: Business planning and performance implications [PDF]

, 2012
Copyright © 2012 by Institution of Mechanical Engineers. This is the author's accepted manuscript. The final published article is available from the link below.Manufacturing firms are under many financial and competitive pressures which focus attention ...
Aurich JC, Davis S, Jacques JJ, McDonough W, Piller FT, Pine BJ, Toffler A   +6 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Investigation of Thermal Stability of Mg₈₄Cu₁₆ as New Potential High-Temperature Phase Change Materials for Latent Heat Storagee

Proceedings
This work examines the thermal stability testing results of Mg84Cu16 as a new phase change material for its potential use in latent thermal energy storage systems for 488 °C transition temperatures.
Yassine El Karim, Abdessamad Faik, Yaroslav Grosu, Rachid Lbibb   +3 more
doaj   +1 more source

A novel hybrid architecture for agriculture and land use in an integrated modeling framework : MATISSE (Methods and Tools for Integrated Sustainability Assesment) [PDF]

, 2008
As part of a cluster workshop on sustainability of hydrogen transport technologies held in Frankfurt on 21st February 2006, MATISSE researchers conducted break-out discussion groups with, and distributed self-completion questionnaires to, stakeholders in
Cassen, Christophe, Crassous, Renaud, Dorin, Bruno, Gitz, Vincent, Hourcade, Jean-Charles   +4 more
core  

Environmental Costs Account: a base for measuring sustainability in transport plans. [PDF]

, 2009
Each city need to develop sustainable transport plans according to its fu-ture developments. This means identifying the best policy package of transport measures that could produce more sustainable future scenarios: lowest environmental impact, but also ...
Fernández Heredia, Álvaro, Jordá Lope, Pablo, Monzón de Cáceres, Andrés   +2 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Biosurfactant production by fungi as a sustainable alternative

Arquivos do Instituto Biológico, 2018
: A wide variety of bacteria is far more exploited than fungi as biosurfactants (BS) or bioemulsifiers (BE), using renewable sources. BS are considered to be environmentally safe and offer advantages over synthetic surfactants.
Artemisia Carla Santos da Silva, Patrícia Nunes dos Santos, Thayse Alves Lima e Silva, Rosileide Fontenele Silva Andrade, Galba Maria Campos-Takaki   +4 more
doaj   +1 more source

Towards reframing professional expert support [PDF]

, 2007
The paper addresses practical ways of reconfiguring professional expertise in development practice in moving away from the expert as a technocrat. Two projects associated with managing natural resource dilemmas suggest an alternative way of framing ...
Reynolds, Martin
core  

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

Molecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker, Elysia Sarsam, Stuart J. Conway, Ester M. Hammond   +3 more
wiley   +1 more source

Product service systems in the automotive industry: An alternative business model for a sustainable satisfaction system [PDF]

, 2008
Copyright @ 2008 Brunel UniversityThe paper presents the intermediate results of an on-going research project called Vehicle Design Summit (VDS), run by an international Consortium of Universities coordinated by the MIT of Boston.
Ceschin, F, Vezzoli, C
core