Results 11 to 20 of about 20,659 (263)

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

DDX54 drives ALKBH5-mediated demethylation of selected transcripts to suppress interferon antiviral response

Journal of Virology
DEAD-box (DDX) proteins are currently reported to shape host innate immunity by regulation of N6-methyladenosine (m6A) modification of transcripts for host factors involved in antiviral signaling.
Hao-Yu Sun, Xiu-Ying Gong, Zi-Ling Qu, Li-Li An, Wen-Hao Guo, Hong-Yu Luan, Meng-Yao Wu, Ji-Cheng Yu, Cheng Dan, Yi-Bing Zhang   +9 more
doaj   +1 more source

Effects of Gallic Acid Supplementation on Intestinal Function and Gut Microbial Community Structure in Holothuria leucospilota

Aquaculture Nutrition
Gallic acid (GA) is a plant-derived polyphenol with antioxidant and antimicrobial activities, yet its efficacy as a functional feed additive in sea cucumbers remains unclear.
Wenjie Pan, Hang Yuan, Chenchen Sun, Jianfeng Xu, Yi Zhang, Zhou Qin, Jingxuan Liang, Fanjiang Ou, Zepeng Zhang, Shuyang Wen, Chunhua Ren, Xiao Jiang, Peng Luo, Aifen Yan, Haipeng Qin, Chaoqun Hu, Ting Chen   +16 more
doaj   +1 more source

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

Oxygen enhances antiviral innate immunity through maintenance of EGLN1-catalyzed proline hydroxylation of IRF3

Nature Communications
Oxygen is essential for aerobic organisms, but little is known about its role in antiviral immunity. Here, we report that during responses to viral infection, hypoxic conditions repress antiviral-responsive genes independently of HIF signaling.
Xing Liu, Jinhua Tang, Zixuan Wang, Chunchun Zhu, Hongyan Deng, Xueyi Sun, Guangqing Yu, Fangjing Rong, Xiaoyun Chen, Qian Liao, Shuke Jia, Wen Liu, Huangyuan Zha, Sijia Fan, Xiaolian Cai, Jian-Fang Gui, Wuhan Xiao   +16 more
doaj   +1 more source

A Global Methane Observation System to Reduce Uncertainty for Anthropogenic and Natural Sources and Sinks for Detecting and Attributing Climate Feedbacks

Advanced Science, EarlyView.
Conceptual illustration of a Global Ecosystem Methane Observing System (GEM‐OS) integrating satellites, aircraft, atmospheric networks, and ecosystem measurements to quantify methane emissions from anthropogenic and natural sources. The multi‐scale observing framework improves source attribution, reduces uncertainty in regional methane budgets, and ...
P. Ciais, S. Peng, J. Chang, F. Li, Q. Zhu, K. Yuan, G. Hugelius, H. Li, Y. Cai, F. Chevallier, K. Tibrewal, E. A. Kort, K. Arndt, J. Watts, B. Buma, N. Besic, P. I. Palmer, H. Cadillo‐Quiroz, E. Euskirchen, M. J. Gondwe, A. Hoyt, R. Jackson, S. Malone, D. Monteverde, S. Natali, M. Ramonet, C. Rey‐Sanchez, L. B. Sagang, E. A. G. Schuur, R. Vargas, R. Varner, Z. Zhang, B. Poulter   +32 more
wiley   +1 more source

Australia’s seafood imports outsource environmental and socioeconomic costs to other nations

Environmental Research: Food Systems
Global seafood consumption has increased over the past six decades, currently providing ∼20% of the world’s per capita protein intake. Australia faces a striking paradox in the global seafood scenario: while having one of the world’s largest fishing ...
A Barbosa Martins, J Smart, M Ciampaglia, M Lonati, A Hoffman, A Berge, M Schlawinsky, K Potgieter, A Pisarczyk, M Hatayama, D Baker, H Razali, L Dayan, J New, R Tobin, A Chin   +15 more
doaj   +1 more source

Spring viremia of carp virus infection induces hypoxia response in zebrafish by stabilizing hif1α

Journal of Virology
The hypoxia signaling pathway controls hypoxia adaptation and tolerance of organisms, which is regulated by multiple mechanisms. Viral infection elicits various pathophysiological responses in the host.
Zixuan Wang, Chunchun Zhu, Xueyi Sun, Hongyan Deng, Wen Liu, Shuke Jia, Yao Bai, Wuhan Xiao, Xing Liu   +8 more
doaj   +1 more source

Asymmetric Single‐Atom Catalysts Govern Diffusible and Non‐Diffusible Non‐Radical Pathways for Selective Degradation of Antibiotic Resistance Genes

Advanced Science, EarlyView.
Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao, Jun Sun, Liang Zhang, Litao Lin, Zongfeng Wan, Bingcai Pan, Sheng Tang   +6 more
wiley   +1 more source

Identification and characterization of a novel reovirus strain isolated fromgrass carp (Ctenopharyngodon idella)

Virology Journal
Background Grass carp (Ctenopharyngodon idella) hemorrhagic disease (GCHD) is a devastating disease that leads to substantial economic losses in the freshwater aquaculture industry.
Weiguang Kong, Guangyi Ding, Qiushi Zhang, Xinjie Yuan, Yuchao Zhu, Liyuan Ma, Chang Cai, Yong Shi, Qianqian Zhang, Zhen Xu   +9 more
doaj   +1 more source