Results 91 to 100 of about 3,087,818 (341)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Education for sustainable development in Malta [PDF]

, 2003
This paper is a 2004 revised version of the case study prepared for the 2003 Expert Meeting on Capacity Development for Sustainable Development in SIDS: Building Partnerships for Sustainable development through Education, Public Awareness and Training ...
Briguglio, Lino, Expert Meeting on Capacity Development for Sustainable Development in SIDS : Building Partnerships for Sustainable Development Through Education, Public Awareness and Training, Pace, Paul J.   +2 more
core  

Exploring Factors Affecting Covid-19 Vaccine Uptake Among African University Students: A Scoping Review

SAGE Open
This scoping review is intended to examine and consolidate the factors that influence the uptake of COVID-19 vaccines among African university students.
Isaac Nyarko Kwakye, Daniel Adom-Fynn, Nuworza Kugbey, Kwame Benyibaling Bour   +3 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

The 2019 SDG Index and Dashboards Report for European Cities : prototype version [PDF]

, 2019
Resumen: Este es el primer informe que analiza los logros de las capitales europeas y de una selección de grandes áreas metropolitanas en la Unión Europea (UE) y la Asociación Europea de Libre Comercio (AELC) en relación a los 17 Objetivos de Desarrollo ...
Sustainable Development Solutions Network, Telos Brabant Centre for Sustainable Development   +1 more
core   +1 more source

Individual behavioral variation reflects personality divergence in the upcoming model organism Nothobranchius furzeri

Ecology and Evolution, 2018
In the animal kingdom, behavioral variation among individuals has often been reported. However, stable among‐individual differences along a behavioral continuum—reflective of personality variation—have only recently become a key target of research. While
Eli S. J. Thoré, Laure Steenaerts, Charlotte Philippe, Arnout Grégoir, Luc Brendonck, Tom Pinceel   +5 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Wind power in the UK : a guide to the key issues surrounding onshore wind power development in the UK [PDF]

, 2012
This report is summarised in the Welsh language in 'Ynni gwynt : ateb eich cwestiynau'.This report is summarised in 'Wind power : your questions answered'.This report aims to help policy-makers and planners balance genuine local concerns with wider ...
Sustainable Development Commission
core  

Conceptual Analysis of Sustainable Development and Sustainable Development.

Investigacion e Innovación en Ingenierias, 2014
El presente artículo es una reflexión  acerca de los conceptos desarrollo sostenible y desarrollo sustentable, términos que generan discusión en su acepción en el ámbito de la gestión ambiental. Para lo cual se desarrolló una revisión de la bibliografía relacionada con el objeto de esta reflexión.
Ludys López Polo, Efraín Javier De La Hoz Granadillo   +1 more
openaire   +3 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source