Results 71 to 80 of about 552,492 (266)

Dairy farmers’ levels of awareness of antibiotic use in livestock farming in Pakistan

Humanities & Social Sciences Communications
Antimicrobial resistance due to the irrational and non-sustainable use of antimicrobials poses a serious threat to animal health, human health and urban food security.
Muhammad Farhan, Namra Awan, Amina Kanwal, Faiza Sharif, Muhammad Umar Hayyat, Laila Shahzad, Gul Zareen Ghafoor   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Profit as a predictor variable for environmental sustainability practices (ESPs) of manufacturing companies for achieving green manufacturing in contemporary Ghana

Cogent Economics & Finance
The complex relationship between profit margins and environmental sustainability practices (ESPs) in Ghana’s manufacturing industry is examined in this study. Utilizing information gathered from six manufacturing firms, the study uses regression analysis
Kwame B. Bour, Kwaku Adu, Anthony Amoah, Braimah Kassum, Collins Gameli Hodoli, Patience A. K. Awua-Boateng   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Examining the social-ecological dimensions of Philippine pangolin (Manis culionensis) conservation

Discover Conservation
Pangolins are the world’s most trafficked mammals due to the persistent international demand for their scales and meat. The critically endangered Philippine pangolin (Manis culionensis) is one of the eight extant pangolin species worldwide. It is endemic
Bryan Joel S. Mariano, Emerson Y. Sy, Lemuel A. Pabico, Neliza Bacani-Tabi, Chiara Graziella Loor, Denise Margaret S. Matias   +5 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Conservation and sustainable development in a VUCA world: the need for a systemic and ecosystem‐based approach

Ecosystem Health and Sustainability, 2017
Targeting the maintenance of functional ecosystems that provide the significant basis for human well‐being is an integral part of an ecosystem‐based sustainable development.
Axel Schick, Peter R. Hobson, Pierre L. Ibisch   +2 more
doaj   +1 more source

Welfare Impacts of Afghan Trade on the Pakistani Provinces of Balochistan and Khyber Pakhtunkhwa

Stability : International Journal of Security and Development, 2015
Amidst all the concerns of uncertainty over the future of Afghanistan, recent developments have given hope to the world, specifically south and central Asia.
Saad Shabbir, Vaqar Ahmed
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Exploring Factors Affecting Covid-19 Vaccine Uptake Among African University Students: A Scoping Review

SAGE Open
This scoping review is intended to examine and consolidate the factors that influence the uptake of COVID-19 vaccines among African university students.
Isaac Nyarko Kwakye, Daniel Adom-Fynn, Nuworza Kugbey, Kwame Benyibaling Bour   +3 more
doaj   +1 more source