Results 61 to 70 of about 6,005,317 (331)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Sustainable machining - correlation of the optimization by minimum energy, minimum manufacturing time and cost of production [PDF]

, 2013
The machining process leads the indices of productivity and employability in a world level and has an enormous influence at social and economics standards, however it requires machinery that consume high levels of energy, chemical fluids and has great ...
Pascoal, Filipa, Silveira, José
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Sustainable turning of AISI 316 stainless steel using copper oxide nanoparticle-enriched sunflower oil: Experimental evaluation and machine learning-based prediction of surface roughness

Results in Engineering
Growing environmental and health concerns associated with conventional metal-cutting fluids (MCFs) have spurred the need for sustainable alternatives in machining processes.
Ammar H. Elsheikh, Mohamed A.E. Omer, Mohamed A. Eladawy, Mohamed H. Sheriff, Medhat M.E. Shalaby, Ahmed M. El-Kassas   +5 more
doaj   +1 more source

A concept of water usage efficiency to support water reduction in manufacturing industry [PDF]

, 2016
Increasing pressures on freshwater supplies, continuity of supply uncertainties, and costs linked to legislative compliance, such as for wastewater treatment, are driving water use reduction up the agenda of manufacturing businesses.
Rahimifard, Shahin, Sachidananda, Madhu, Webb, D. Patrick   +2 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Sustainability Assessment during Machining Ti-6Al-4V with Nano-Additives-Based Minimum Quantity Lubrication

Journal of Manufacturing and Materials Processing, 2019
The implementation of sustainable machining process can be accomplished by different strategies including process optimization and selection of the proper lubrication techniques and cutting conditions.
Hossam A. Kishawy, Hussien Hegab, Ibrahim Deiab, Abdelkrem Eltaggaz   +3 more
doaj   +1 more source

An investigation into reducing the spindle acceleration energy consumption of machine tools [PDF]

, 2016
Machine tools are widely used in the manufacturing industry, and consume large amount of energy. Spindle acceleration appears frequently while machine tools are working. It produces power peak which is highly energy intensive. As a result, a considerable
Jia, Shun, Liu, Ying, Lv, Jingxiang, Tang, Renzhong, Tang, Wangchujun, Zhang, Yingfeng   +5 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source