Results 81 to 90 of about 6,005,317 (331)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Machine learning for computational sustainability [PDF]

open access: yes2012 International Green Computing Conference (IGCC), 2012
To avoid ecological collapse, we must manage Earth's ecosystems sustainably. Viewed as a control problem, the two central challenges of ecosystem management are to acquire a model of the system that is sufficient to guide good decision making and then optimize the control policy against that model. This paper describes three efforts aimed at addressing
Tom Dietterich   +3 more
openaire   +1 more source

Evaluation of tool wear, energy consumption, and surface roughness during turning of inconel 718 using sustainable machining technique

open access: yes, 2020
Heat resistant alloys such as Inconel 718 present challenges to manufacturing industries during its machining. Machinability of such alloys can be improved using smart cutting conditions. Further, to seek improvements in the machinability of Inconel 718,
Navneet Khanna   +3 more
semanticscholar   +1 more source

Dry sliding friction and wear response of WC-Co hardmetal pairs in linearly reciprocating and rotating contact [PDF]

open access: yes, 2011
This paper presents an experimental evaluation of friction and wear properties of WC-Co cemented carbides. A comparison is made between unlubricated rotating and linearly reciprocating pin-onplate sliding pairs. The plate specimens were WC-10wt%Co grades
Bonny, Koenraad   +7 more
core   +1 more source

Generation of Micro Mechanical Devices Using Stereo Lithography [PDF]

open access: yes, 2006
A high resolution machining setup for creating three-dimensional precision components from a UV-curable photo-resin has been developed. By using frequency-converted diode-pumped solid state lasers, functional micro-mechanical devices are directly ...
Himmelhuber, R.   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Life cycle assessment (LCA) applied to the process industry: a review [PDF]

open access: yes, 2011
Purpose : Life cycle assessment (LCA) methodology is a well-established analytical method to quantify environmental impacts, which has been mainly applied to products. However, recent literature would suggest that it has also the potential as an analysis
Jacquemin, Leslie   +2 more
core   +6 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Optimization and analysis of cutting parameters using cryogenic media in machining of high strength alloy steel [PDF]

open access: yes, 2013
In this research, liquid Argon is used as a cryogenic media to optimize the cutting parameters for evaluation of tool flank wear width of Tungsten Carbide Insert (CNMG 120404-WF 4215) while turning high strength alloy steel.
Ali, Liaqat   +5 more
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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