Results 71 to 80 of about 624,117 (335)

Nanocellulose in Textiles: A Potential Resource for Sustainable Textile Manufacturing [PDF]

, 2023
Sayam Sayam
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

From failure to success: a framework for successful deployment of Industry 4.0 principles in the aerospace industry [PDF]

International Journal of Industrial Engineering and Operations Management
Purpose – The paper proposes a framework for the successful deployment of Industry 4.0 (I4.0) principles in the aerospace industry, based on identified success factors.
Sumit Gupta, Deepika Joshi, Sandeep Jagtap, Hana Trollman, Yousef Haddad, Yagmur Atescan Yuksek, Konstantinos Salonitis, Rakesh Raut, Balkrishna Narkhede   +8 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Natural Language Processing (NLP)-Based Frameworks for Cyber Threat Intelligence and Early Prediction of Cyberattacks in Industry 4.0: A Systematic Literature Review

Applied Sciences
This study provides a systematic overview of Natural Language Processing (NLP)-based frameworks for Cyber Threat Intelligence (CTI) and the early prediction of cyberattacks in Industry 4.0. As digital transformation accelerates through the integration of
Majed Albarrak, Konstantinos Salonitis, Sandeep Jagtap   +2 more
doaj   +1 more source

Conceptual Framework of a Digital Twin Fostering Sustainable Manufacturing in a Brownfield Approach of Small Volume Production for SMEs [PDF]

, 2023
Sandra Krommes, Florian Tomaschko
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

IMPACT OF AMT INVESTMENTS ON EFFECTIVENESS AND COMPETITIVENESS OF MANUFACTURING SYSTEMS [PDF]

Every manufacturing company is a system of individual manufacturing units, which have to be carefully laid out taking into account time, space, technology, and organisation perspective in order to deliver maximum final product.
Miroslav Chodur, Premysl Palka
core  

The potential of additive manufacturing in the smart factory industrial 4.0: A review [PDF]

, 2019
Additive manufacturing (AM) or three-dimensional (3D) printing has introduced a novel production method in design, manufacturing, and distribution to end-users.
Dehghanghadikolaei, Amir, Emamian, Sattar S., Fotovvati, Behzad, Gisario, Annamaria, Mehrpouya, Mehrsha, Vosooghnia, Alireza   +5 more
core   +1 more source

Eco‐Holonic 4.0 Circular Business Model to  Conceptualize Sustainable Value Chain Towards  Digital Transition  [PDF]

, 2020
The purpose of this paper is to conceptualize a circular business model based on an Eco-Holonic Architecture, through the integration of circular economy and holonic principles.
Aguayo-González, Francisco, Lama-Ruiz, Juan Ramón, Martín-Gómez, Alejandro Manuel, Ávila-Gutiérrez, María Jesús   +3 more
core   +1 more source