Results 61 to 70 of about 4,253,121 (312)

Iron-sulphur protein catalysed [4+2] cycloadditions in natural product biosynthesis

Nature Communications
To the best of our knowledge, enzymes that catalyse intramolecular Diels-Alder ([4+2] cycloaddition) reactions are frequently reported in natural product biosynthesis; however, no native enzymes utilising Lewis acid catalysis have been reported ...
Yu Zheng, Katsuyuki Sakai, Kohei Watanabe, Hiroshi Takagi, Yumi Sato-Shiozaki, Yuko Misumi, Yohei Miyanoiri, Genji Kurisu, Toshihiko Nogawa, Ryo Takita, Shunji Takahashi   +10 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Sustainable communities policy review : Stoke [PDF]

, 2012
This report is part of the evidence base for 'In-depth review of sustainable communities policy'.This paper includes evidence collated from an Sustainable Development Commission visit, Audit Commission North Staffordshire Pathfinder report (2004) and ...
Sustainable Development Commission
core  

Chemical characterization and nutritional potential of a Costa Rican edible cricket (Gryllus sp.) for human consumption

Frontiers in Nutrition
This study characterized the morphology, proximate composition, micronutrient profile, amino acid distribution, and fatty acid composition of a Gryllus sp. powder to evaluate its nutritional quality.
Ana María Quirós, Ana María Quirós, Milieth Arias-Leitón, Milieth Arias-Leitón, Sergio Jansen-González, Graciela Artavia, Luis Ricardo Murillo-Hiller, Luis Ricardo Murillo-Hiller, Viky Calero, Oscar Abel Sánchez-Velázquez, Oscar Acosta   +10 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Public attitudes to sustainable development [PDF]

, 2012
There is a lot of information around on public attitudes to sustainable development, with varying degrees of reliability and relevance. Most of the work referred to here is UK based and comes from DETR, the British Social Attitudes survey and MORI ...
Sustainable Development Commission
core  

Sustainable Protein Transitions: A Comprehensive Review of Insect Meal in Broiler Diets—Nutritional Value, Immunomodulatory Effects, Gut Health Interactions, and Future Perspectives

Biology
Broiler production keeps intensifying, and the environmental cost of the protein sources that feed it, principally soybean meal and fishmeal, has become harder to justify.
Osama K. Abou-Emera
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Leading by example? : not exactly… : SDC commentary on the Sustainable Development in Government Report 2005 [PDF]

, 2012
Sustainable Development Commission commentary on the 'Sustainable Development in Government Report 2005'.Publisher ...
Sustainable Development Commission
core  

Development of Value-Added Food Products from European Catfish (Silurus glanis) to Support Its Valorisation and Capture in the Tagus River, Portugal

Foods
The European catfish (Silurus glanis) is an invasive predatory species threatening biodiversity in the Tagus River (Portugal), while remaining underexploited as a food resource.
João Reis, Irene Cristina Antunes, Gabriela Basto de Lima, Ana Teresa Ribeiro, Ana Neves, Luísa Cristina Roseiro, Nuno Alvarenga, Helena Gonçalves, Jaime Fernandes, Mafalda Silva, Elsa M. Gonçalves, Sandra Fernandes Gomes, Manuela Lageiro, Andreia Soares, Paula Pinto, Igor Dias   +15 more
doaj   +1 more source