Metabolite Biomarkers of Leishmania Antimony Resistance [PDF]
Cells, 2021 Leishmania parasites cause leishmaniasis, one of the most epidemiologically important neglected tropical diseases. Leishmania exhibits a high ability of developing drug resistance, and drug resistance is one of the main threats to public health, as it is
Sneider Alexander Gutierrez Guarnizo +3 more
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Towards Bioprospection of Commercial Materials of Mentha spicata L. Using a Combined Strategy of Metabolomics and Biological Activity Analyses [PDF]
Molecules, 2022 Spearmint (Mentha spicata L.) has been widely studied for its diversity of compounds for product generation. However, studies describing the chemical and biological characteristics of commercial spearmint materials from different origins are scarce.
Juan Camilo Henao-Rojas +8 more
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Natural Biflavonoids Modulate Macrophage–Oxidized LDL Interaction In Vitro and Promote Atheroprotection In Vivo [PDF]
Frontiers in Immunology, 2017 The accumulation of oxidized ApoB-100-containing lipoproteins in the vascular intima and its subsequent recognition by macrophages results in foam cell formation and inflammation, key events during atherosclerosis development.
Jorge H. Tabares-Guevara +9 more
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Histochemical Localization and Cytotoxic Potential of Alkaloids in Phaedranassa lehmannii [PDF]
PlantsPlants of the subfamily Amaryllidoideae are a source of unique and bioactive alkaloids called Amaryllidaceae alkaloids. The study of their anticancer potential has intensified in recent years.
Lina M. Trujillo Chacón +6 more
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Essential oils from Colombian Croton spp. exhibit antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and ampicillin- and streptomycin-resistant Escherichia coli [PDF]
Scientific ReportsBacterial resistance, a global public health concern prioritized by the World Health Organization, is particularly alarming in Staphylococcus aureus and Escherichia coli.
Isabel Cristina Sánchez +4 more
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Preventive Effect of Quercetin in a Triple Transgenic Alzheimer’s Disease Mice Model [PDF]
Molecules, 2019 Alzheimer’s disease (AD) is the most common type of dementia and is the leading cause of disability in elderly people worldwide. Current pharmacological therapies do not cure the disease, and for this reason, some pharmacotherapy studies have ...
Pérez-Corredor Paula +3 more
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ManglarLa producción de plátano Musa AAB en el Ecuador desempeña un papel fundamental en la economía y la seguridad alimentaria. La presencia de nematodos, causan grandes problemas significativos en el cultivo al conllevar a pérdidas económicas muy ...
Manuel Adrian Vallejo Loja +3 more
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Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages [PDF]
Redox Biology, 2018 Oxidized low-density lipoprotein (oxLDL) is a well-recognized proatherogenic particle that functions in atherosclerosis. In this study, we established conditions to generate human oxLDL, characterized according to the grade of lipid and protein oxidation,
Oscar J. Lara-Guzmán +9 more
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Multidimensional Perspective on the Quality of Green Onion: Between the Visible, the Measurable, and the Perceived. [PDF]
Food Sci NutrThis graphical abstract presents a five‐phase framework to define green onion quality by integrating literature evidence, physicochemical and bioactive data, digital trends, field damage observations, and consumer perception, providing a multidimensional and measurable quality assessment.
Castaño-Tarazona LW +2 more
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Optimization of Indole- and Pyrazole-fused Glycyrrhetinic Acid Derivatives as Potent PTP1B Inhibitors: In Silico, In Vitro, In Vivo, and Metabolomic Studies [PDF]
ACS Bio & Med Chem AuMitzi López-Sánchez +11 more
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