Results 91 to 100 of about 1,505,117 (285)
Over the past few decades there has been a growing interest into social learning in animals. The importance of social influence on food choice has been demonstrated across a number of species including humans.
Gladez Shorland +2 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
LexInfo: A declarative model for the lexicon-ontology interface [PDF]
Cimiano P, Buitelaar P, McCrae J, Sintek M. LexInfo: A declarative model for the lexicon-ontology interface. Journal of Web Semantics: Science, Services and Agents on the World Wide Web.
P. Buitelaar +7 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
An upward trend has been observed in recent years in which consumers are actively more conscious about finding healthier food alternatives to purchase. Based on the constantly increasing demands of the diabetes food market, a new product of canned peach ...
Ioannis Prodromos Papachristoudis +4 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Plants with sweetening properties
En razón de que los endulzantes de origen vegetal ofrecen amplias perspectivas como sucedáneos de sacarosa, se efectuó una recopilación de los conocimientos actuales sobre los mismos y sus potenciales aplicaciones.As plants with sweetening properties ...
Mandrile, Eloy L. +2 more
core
The results of identification of the main operational properties of metallocomplex catalysts solutions for non-extractive oxidative sweetening of natural hydrocarbons and their products are provided in this article. These catalysts allow carrying out the
Yu. A. Gavrilo +2 more
doaj
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source

