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Development and Clinical Applications of a 5-Plex Real-Time RT-PCR for Swine Enteric Coronaviruses [PDF]

open access: yesViruses, 2022
A PEDV/PDCoV/TGEV/SADS-CoV/XIPC 5-plex real-time RT-PCR was developed and validated for the simultaneous detection and differentiation of four swine enteric coronaviruses (PEDV, PDCoV, TGEV and SADS-CoV) in one PCR reaction (XIPC serves as an exogenous ...
Jin-Hui Zhu   +9 more
doaj   +6 more sources

Coinfection and nonrandom recombination drive the evolution of swine enteric coronaviruses [PDF]

open access: yesEmerging Microbes and Infections
Coinfection with multiple viruses is a common phenomenon in clinical settings and is a crucial driver of viral evolution. Although numerous studies have demonstrated viral recombination arising from coinfections of different strains of a specific species,
Jiahui Guo   +8 more
doaj   +6 more sources

Swine Enteric Coronaviruses (PEDV, TGEV, and PDCoV) Induce Divergent Interferon-Stimulated Gene Responses and Antigen Presentation in Porcine Intestinal Enteroids [PDF]

open access: yesFrontiers in Immunology, 2022
Swine enteric coronaviruses (SECoVs) including porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), and porcine deltacoronavirus (PDCoV), account for the majority of lethal watery diarrhea in neonatal pigs and pose ...
Lingdan Yin   +5 more
doaj   +7 more sources

Interplay between swine enteric coronaviruses and host innate immune [PDF]

open access: yesFrontiers in Veterinary Science, 2022
Swine enteric coronavirus (SeCoV) causes acute diarrhea, vomiting, dehydration, and high mortality in neonatal piglets, causing severe losses worldwide.
Mingwei Li, Longjun Guo, Li Feng
doaj   +4 more sources

Prevention and Control of Swine Enteric Coronaviruses in China: A Review of Vaccine Development and Application [PDF]

open access: yesVaccines, 2023
Swine enteric coronaviruses (SECs) cause significant economic losses to the pig industry in China. Although many commercialized vaccines against transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV) are available, viruses ...
Fanzhi Kong   +4 more
doaj   +4 more sources

Rapid and efficient detection methods of pathogenic swine enteric coronaviruses. [PDF]

open access: yesAppl Microbiol Biotechnol, 2020
Porcine enteric coronaviruses (CoVs) cause highly contagious enteric diarrhea in suckling piglets. These COV infections are characterized by clinical signs of vomiting, watery diarrhea, dehydration, and high morbidity and mortality, resulting in significant economic losses and tremendous threats to the pig farming industry worldwide.
Fu Y, Li B, Liu G.
europepmc   +6 more sources

Role of heat shock protein 90 as an antiviral target for swine enteric coronaviruses. [PDF]

open access: yesVirus Res, 2023
A variety of swine enteric coronaviruses (SECoVs) have emerged and are prevalent in pig populations, including porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine deltacoronavirus (PDCoV), and swine acute diarrhea syndrome (SADS)-CoV, a newly identified bat-origin CoV with zoonotic potential.
Zhao Z   +6 more
europepmc   +5 more sources

Different Infectivity of Swine Enteric Coronaviruses in Cells of Various Species [PDF]

open access: yesPathogens
Swine enteric coronaviruses (SECoVs), including porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), and swine acute diarrhea syndrome coronavirus (SADS-CoV), have caused high mortality in ...
Zhongyuan Li   +4 more
doaj   +4 more sources

Nucleocapsid proteins from other swine enteric coronaviruses differentially modulate PEDV replication. [PDF]

open access: yesVirology, 2020
Porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV) and porcine deltacoronavirus (PDCoV) share tropism for swine intestinal epithelial cells. Whether mixing of viral components during co-infection alters pathogenic outcomes or viral replication is not known.
Sungsuwan S   +2 more
europepmc   +3 more sources

Detection and Genetic Diversity of Porcine Coronavirus Involved in Diarrhea Outbreaks in Spain [PDF]

open access: yesFrontiers in Veterinary Science, 2021
Porcine enteric coronaviruses include some of the most relevant viral pathogens to the swine industry such as porcine epidemic diarrhea virus (PEDV) or porcine transmissible gastroenteritis virus (TGEV) as well as several recently identified virus such ...
Héctor Puente   +5 more
doaj   +3 more sources

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