Results 91 to 100 of about 3,904 (165)

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez, Julio García‐Cordero, Gabriela Navarro‐Tovar, Leticia Cedillo‐Barrón   +3 more
wiley   +1 more source

Spatial Patterns of Global Peste Des Petits Ruminants Virus and Its Potential Risk Assessment for Various Wildlife Habitats

Ecology and Evolution, Volume 15, Issue 12, December 2025.
This study found that according to the analysis of PPR epidemic data from 2007 to 2024, the driving mechanism of key climatic and environmental factors such as temperature seasonality (standard deviation × 100) (Bio4), annual mean temperature (Bio1), isothermality (Bio3), mean diurnal range (Bio2), mean monthly precipitation in March (Prec3), and the ...
Guiping Lu, Feng Jiang, Rui Zhang, Jialong Guo, Lei Si, Wenrui Jiao, Daoxin Liu, Jingjie Zhang   +7 more
wiley   +1 more source

Engineered Low‐Endotoxin Bacterial Biomimetic Vesicles for Enhanced Oral Dual‐Antigen Subunit Vaccine Delivery

Journal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
A genetically engineered low‐endotoxin Salmonella choleraesuis biomimetic vesicle (CSS‐BBV), coated with COS, is utilized to enhance the oral delivery efficacy of subunit vaccines. The modular SpyCatcher/SpG design enables rapid dual‐antigen conjugation, providing a versatile platform for the development of infectious disease vaccines. ABSTRACT Subunit
Xuegang Shen, Shujie Wang, Kunying Qiu, Zeqing Liu, Xiaoxiao Tian, Fandan Meng, Yan‐Dong Tang, Haiwei Wang, Mingxia Sun, Xue‐Hui Cai, Tong‐Qing An, Yong‐Bo Yang   +11 more
wiley   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

In vitro and in vivo evaluation of thapsigargin as an antiviral agent against transmissible gastroenteritis virus

Veterinary Research
Swine enteric coronaviruses (SeCoVs) pose a significant threat to the global pig industry, but no effective drugs are available for treatment. Previous research has demonstrated that thapsigargin (TG), an ER stress inducer, has broad-spectrum antiviral ...
Yang Li, Yuanyuan Liu, Yunhang Zhang, Chen Tan, Yifei Cai, Yue Zhang, Jianing Chen, Yuguang Fu, Guangliang Liu   +8 more
doaj   +1 more source

Prevalence of enteric pathogens in diarrheic and non-diarrheic samples from pig farms with neonatal diarrhea in the North East of Spain [PDF]

, 2019
Diarrhea is one of the major causes of neonatal mortality in pigs. In the present study, 31 pig farms with outbreaks of neonatal diarrhea were investigated in Catalonia (NE Spain) from February 2017 until June 2018.
Darwich, Laila, Martín, Marga, Martín-Valls, Gerard E., Mateu, Enric, Tello, Montse, Vidal, Anna   +5 more
core   +1 more source

Neonatal porcine diarrhoea [PDF]

, 2016
Diarrhoea in newborn piglets is an old but still relevant problem in pig production globally. During the last decades, reports from a number of countries describe problems with neonatal porcine diarrhoea (NPD) despite the use of previously effective ...
Larsson, Jenny
core  

Advances research in porcine enteric coronavirus therapies and antiviral drugs

Veterinary Quarterly
The porcine enteric coronaviruses (PECs) currently reported include porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), and swine acute diarrhea syndrome coronavirus (SADS-CoV).
Jixiang Liang, Weihang Xu, Xiaoming Pan, Shiyun Han, Linwei Zhang, Hao Wen, Mingyue Ding, Wanpo Zhang, Dapeng Peng   +8 more
doaj   +1 more source

A novel double-antibody sandwich ELISA based on monoclonal antibodies against the viral spike protein detects porcine deltacoronavirus infection

Microbiology Spectrum
Porcine deltacoronavirus (PDCoV) is a significant emerging pathogen that causes severe enteric disease in swine, and therefore significant economic losses in the pig farming industry.
Yingjie Bai, Ruiming Yu, Guangqing Zhou, Liping Zhang, TianTian Wang, Ya Liu, Dongsheng Wang, Zhongwang Zhang, Yonglu Wang, Huichen Guo, Li Pan, Xinsheng Liu   +11 more
doaj   +1 more source