Results 31 to 40 of about 29,169 (246)
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Vortices produced by swirl-mixing grids in nuclear fuel assembly: a wind-tunnel experiment
FlowLongitudinal vortices produced by a swirl-mixing grid are experimentally explored in an upscaled model of nuclear fuel assembly. The flow is mapped using particle image velocimetry in several planes downstream of the grid.
Matěj Dolejš +7 more
doaj +1 more source
An experimental study on premixed CNG/H2/CO2 mixture flames
Open Engineering, 2018 In this study, the effect of swirl number, gas composition and CO2 dilution on combustion and emission behaviour of CNG/H2/CO2 gas mixtures was experimentally investigated in a laboratory scale combustor.
Yilmaz Ilker, Yilmaz Harun, Cam Omer
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
0/1 and 3 - dimensional cold flow analysis of a diesel engine: A case study
International Journal of Automotive Science and TechnologyGas motion in the engine cylinder plays a critical role in diesel engines' air-fuel mixing and combustion processes. Moreover, it influences the engine's performance, emissions, and heat transfer.
Gonca Kethudaoglu +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Swirl sign in intracerebral haemorrhage: definition, prevalence, reliability and prognostic value
BMC Neurology, 2012 Background Swirl sign has previously been described in epidural hematomas as areas of low attenuation, radiolucency or irregular density. The aims of this study were to describe swirl sign in ICH, study its prevalence, study the reliability of the ...
Selariu Eufrozina +3 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
LES evaluation of the effects of equivalence ratio fluctuations on the dynamic flame response in a real gas turbine combustion chamber [PDF]
, 2013 Large Eddy Simulations (LES) of a lean swirl-stabilized gas turbine burner are used to analyze mechanisms triggering combustion instabilities. To separately study the effect of velocity and equivalence ratio fluctuations, two LES of the same geometry are
Hermeth, Sebastian +4 more
core +1 more source
Applications in Energy and Combustion Science, 2023 Ammonia is an attractive clean fuel for its potential to reduce CO2 emission and fossil fuel consumption. However, ammonia combustion has been mainly discouraged by the low flammability and the high fuel NOx emissions. This study numerically investigates
Junqing Zhang +3 more
doaj +1 more source