Results 61 to 70 of about 1,943,775 (315)

Possibility to increase the speeds of express and high-speed trains by turnouts and connecting tracks

Вестник Научно-исследовательского института железнодорожного транспорта, 2016
The possibility of increasing motion speeds of express (“Lastochka”) and high-speed (“Sapsan”) electric trains by the side direction of express (project 2726) and high-speed railway (project 2956) switches is experimentally investigated.
A. M. Brzhezovskiy, B. E. Glyuzberg, M. I. Titarenko, I. E. Il’In, V. S. Viktorov, V. N. Tulushev   +5 more
doaj   +1 more source

Tunable THz and Infrared Plasmonic Filters and Switches Based on Circular Graphene Resonator With 90$^\circ$ Bending of Output Port

IEEE Photonics Journal, 2020
Two types of novel graphene-based components, namely, filters and electro-optical switches in guided wave configuration are suggested and analysed. The filters differ from the known ones with collinear orientation of the input and output waveguides by ...
Victor Dmitriev, Geraldo Melo, Wagner Castro   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Engineering solutions to improve conditions and smoothness of train traffic on turnout switches

Вестник Научно-исследовательского института железнодорожного транспорта
Introduction. The currently used turnout switches geometries provided for the development and serial production of the main types of turnout equipment that ensure the transport process on the Russian railways.
Boris E. Glyuzberg, Pavel V. Tregubchak, Il'ya V. Tsittser   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Composition and liquid-to-solid maturation of protein aggregates contribute to bacterial dormancy development and recovery

Nature Communications
Recalcitrant bacterial infections can be caused by various types of dormant bacteria, including persisters and viable but nonculturable (VBNC) cells.
Celien Bollen, Sofie Louwagie, Femke Deroover, Wouter Duverger, Ladan Khodaparast, Laleh Khodaparast, Dieter Hofkens, Joost Schymkowitz, Frederic Rousseau, Liselot Dewachter, Jan Michiels   +10 more
doaj   +1 more source

A New Flow Entry Replacement Scheme Considering Traffic Characteristics in Software-Defined Networks

Applied Sciences, 2020
The Software Defined Network (SDN) decouples control and data planes of the existing network architecture and a controller carries out centralized management and control of the network.
Namgi Kim, Dongyeol Kim, Yehoon Jang, Chansu Lee, Byoung-Dai Lee   +4 more
doaj   +1 more source

Disparate bilingual experiences modulate task-switching advantages: A diffusion-model analysis of the effects of interactional context on switch costs.

Cognition, 2016
Drawing on the adaptive control hypothesis (Green & Abutalebi, 2013), we investigated whether bilinguals' disparate interactional contexts modulate task-switching performance.
A. Hartanto, Hwajin Yang
semanticscholar   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source