Results 41 to 50 of about 1,943,775 (315)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Micromachines, 2022 In this work, an mm-wave/THz MEMS switch design process is presented. The challenges and solutions associated with the switch electrical design, modeling, fabrication, and test are explored and discussed.
Yukang Feng +2 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Energetic profiling reveals thermodynamic principles underlying amyloid fibril maturation
Nature CommunicationsAmyloid fibrils adopt diverse structural polymorphs linked to disease-specific phenotypes, but the thermodynamic principles guiding their formation and maturation remain unclear.
Ramon Duran-Romaña +3 more
doaj +1 more source
Counterrail design with increased service life for advanced turnout switches
Вестник Научно-исследовательского института железнодорожного транспортаIntroduction. Counterrail is one of the constructive elements of modern turnout switches, which requires increased service life. The impact of railway rolling stock wheels on the counterrails causes high bending stresses in the elements of attachment to ...
M. E. Berezovskii
doaj +1 more source
Research of a Virtual Infrastructure Network with Hybrid Software-Defined Switching
Engineering Proceedings, 2023 Modern trends in the information technology have led to the fact that entire systems of infrastructure are becoming software-defined. Modern hyper-converged solutions use software-defined networking and soft switches for the hypervisor networking ...
Yuri Ushakov +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Journal of NanobiotechnologyBackground Inclusion bodies (IBs) are well-known subcellular structures in bacteria where protein aggregates are collected. Various methods have probed their structure, but single-cell spectroscopy remains challenging.
Wouter Duverger +6 more
doaj +1 more source
Cancer—A Pragmatic Switch to Combat Metabolic Syndrome?
Oncology Reviews, 2023 Both cancer and metabolic disease have become the prevalent health risks in modern societies worldwide. Cancer is a complex set of illnesses with many definitions. About 15% of cancers are caused by infections, and 10% carry a hereditary burden.
John Claras
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New molecular switch architectures
Proceedings of the National Academy of Sciences of the United States of America, 2018 In this paper we elaborate on recently developed molecular switch architectures and how these new systems can help with the realization of new functions and advancement of artificial molecular machines.
Jared D. Harris +2 more
semanticscholar +1 more source