Results 21 to 30 of about 1,943,775 (315)

Switching Portfolios [PDF]

International Journal of Neural Systems, 1997
A constant rebalanced portfolio is an asset allocation algorithm which keeps the same distribution of wealth among a set of assets along a period of time. Recently, there has been work on on-line portfolio selection algorithms which are competitive with the best constant rebalanced portfolio determined in hindsight (Cover, 1991; Helmbold et al., 1996;
openaire   +3 more sources

Switching Off the Switch [PDF]

Structure, 2003
AbstractThe solution structure of the catalytic domain of the dual-specificity phosphatase PAC-1 reveals new insight about the enzymes that deactivate mitogen-activated protein kinases (MAPK).
Selenko, Philipp, Sattler, Michael
openaire   +1 more source

Class-Switch Recombination Occurs Infrequently in Germinal Centers.

Immunity, 2019
Class-switch recombination (CSR) is a DNA recombination process that replaces the immunoglobulin (Ig) constant region for the isotype that can best protect against the pathogen.
Jonathan A. Roco, L. Mesin, S. Binder, C. Nefzger, Paula Gonzalez-Figueroa, Pablo F Cañete, J. Ellyard, Q. Shen, Philippe A. Robert, J. Cappello, H. Vohra, Yang Zhang, Carla R Nowosad, Ariën Schiepers, L. Corcoran, K. Toellner, J. Polo, M. Meyer-Hermann, G. Victora, C. Vinuesa   +19 more
semanticscholar   +1 more source

Exosome‐Guided Phenotypic Switch of M1 to M2 Macrophages for Cutaneous Wound Healing

Advancement of science, 2019
Macrophages (Mϕs) critically contribute to wound healing by coordinating inflammatory, proliferative, and angiogenic processes. A proper switch from proinflammatory M1 to anti‐inflammatory M2 dominant Mϕs accelerates the wound healing processes leading ...
Hyosuk Kim, Sun Young Wang, Gijung Kwak, Yoosoo Yang, I. Kwon, Sun Hwa Kim   +5 more
semanticscholar   +1 more source

ScienceBox 2.0: Evolving the demonstrator package for CERN storage and analysis services [PDF]

EPJ Web of Conferences
With containers being the de-facto standard to package, distribute, and run applications, Helm charts are on the rise for application deployment in managed clusters (e.g., Kubernetes, OpenShift), providing developers and operators with a rich ecosystem ...
Bocchi Enrico, Desai Jimil, Alfageme Sainz Samuel   +2 more
doaj   +1 more source

Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis

Nature Communications, 2018
Aggregation is sequence-specific and nucleated by short aggregating protein segments (APR). Here authors use a multidisciplinary approach to show that in E.coli some frequently occurring APRs lead to protein aggregation and ultimately bacterial cell ...
Ladan Khodaparast, Laleh Khodaparast, Rodrigo Gallardo, Nikolaos N. Louros, Emiel Michiels, Reshmi Ramakrishnan, Meine Ramakers, Filip Claes, Lydia Young, Mohammad Shahrooei, Hannah Wilkinson, Matyas Desager, Wubishet Mengistu Tadesse, K. Peter R. Nilsson, Per Hammarström, Abram Aertsen, Sebastien Carpentier, Johan Van Eldere, Frederic Rousseau, Joost Schymkowitz   +19 more
doaj   +1 more source

Flipping the Metabolic Switch: Understanding and Applying Health Benefits of Fasting

Obesity, 2017
Intermittent fasting (IF) is a term used to describe a variety of eating patterns in which no or few calories are consumed for time periods that can range from 12 hours to several days, on a recurring basis.
S. Anton, Keelin Moehl, W. Donahoo, Krisztina Marosi, Stephanie A Lee, A. Mainous, C. Leeuwenburgh, M. Mattson   +7 more
semanticscholar   +1 more source

Low-Voltage and High-Reliability RF MEMS Switch with Combined Electrothermal and Electrostatic Actuation

Micromachines, 2021
In this paper, we report a novel laterally actuated Radio Frequency (RF) Microelectromechanical Systems (MEMS) switch, which is based on a combination of electrothermal actuation and electrostatic latching hold.
Yong Zhu, Jitendra Pal
doaj   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Next-Gen Storage Infrastructure for ALICE [PDF]

EPJ Web of Conferences
ALICE introduced ground-breaking advances in data processing and storage requirements and presented the CERN IT data center with new challenges with the highest data recording requirement of all experiments.
Peters Andreas Joachim, Sindrilaru Elvin Alin, Betev Latchezar, Contescu Cristian, Del Monte Gianmaria, Ducret Vincent, Grigoras Costin, Lamanna Massimo, Mascetti Luca, Panzer-Steindel Bernd, Pomponi Daniele   +10 more
doaj   +1 more source