Results 81 to 90 of about 855,591 (295)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Analysis of exponential stability and L1-gain performance of positive switched impulsive systems with all unstable subsystems

Nonlinear Analysis
This article investigates the exponential stability and L1-gain performance of time-varying positive switched impulsive systems even when all modes are unstable.
Xiukun Zhang, Yuangong Sun, Xingao Zhu
doaj   +1 more source

Future DCS objectives in communication network timing and synchronization [PDF]

The Defense Communication System will be moving rapidly toward providing switched digital service to it's users within the next ten years. The principal driving force in the transition to a digital system is the requirement for high performance secure ...
Mensch, J. R.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Robust Stability of Switched Interconnected Systems with Switching Uncertainties

Mathematics
This paper investigates the problem of robust stability for a class of switched interconnected systems characterized by unstable modes, time-varying state delays, and switching uncertainties.
Huanbin Xue, Xiaopeng Yang
doaj   +1 more source

MSAT network architecture [PDF]

The Mobile Satellite (MSAT) communications system will support mobile voice and data services using circuit switched and packet switched facilities with interconnection to the public switched telephone network and private networks.
Davies, N. G., Skerry, B.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Two-Layer Security for Image Encryption: A Switched System Approach

IEEE Access
This paper proposes an image encryption-decryption scheme with two-layer security. In the first layer, an image is encrypted by a switched system, using the concept from control theory.
Uyen L. P. Nguyen, Long Tonthat, Vo-Tan Phuoc, Lap Luat Nguyen   +3 more
doaj   +1 more source

Symmetrical angle switched single-phase and three-phase rectifiers: application to micro hydro power plants [PDF]

, 2019
Micro-size hydro power plants are commonly used at remote areas to supply islanded AC microgrids. A typical way to control grid frequency is to manipulate active power dissipated in ballast loads by AC/AC converters.
Bory Prevez, Henry, Majanne, Yrjö, Martínez García, Herminio, Vazquez Seisdedos, Luis   +3 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source