Results 101 to 110 of about 712,860 (302)

Control Stimuli in Experimental Code-Switching Research

open access: yesLanguages, 2019
The current study investigates whether there is variation among different types of control stimuli in code-switching (CS) research, how such stimuli can be used to accommodate heterogeneity, and how they can also be used as a baseline comparison of ...
Bryan Koronkiewicz
doaj   +1 more source

Survey of switching techniques in high-speed networks and their performance [PDF]

open access: yes, 1989
One of the most promising approaches for high speed networks for integrated service applications is fast packet switching, or ATM (Asynchronous Transfer Mode).
Kolson, David   +4 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

How to switch on a master switch

open access: yesJournal of Experimental Botany
This article comments on: Hu Y, Lin Y, Bai J, Xu X, Wang Z, Ding C, Ding Y, Chen L. 2024. AMPK activator 991 specifically activates SnRK1 and thereby affects seed germination in rice. Journal of Experimental Botany 75, 2917–2932.
Kaur, N., Halford, N. G.
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Engineering test procedure for the patient assist device [PDF]

open access: yes
The test procedure completely tests the functioning of the patient assist device. All modes of operation are included in the test. Patient activated switches may be chosen for use with this device as desired. These switches, however, must be single-pole,
Schroder, M. A.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

To Switch or Not to Switch: Code-switching in a Multilingual Country

open access: yesProcedia - Social and Behavioral Sciences, 2015
AbstractThis paper presents a theoretical review of several aspects concerning the linguistic phenomenon of code-switching. The review includes some terms which stand at the basis of communication; code-switching; its existence as a bilingual and multilingual phenomenon; the multilingual reality in Israel, and lastly, code-switching in the FL classroom.
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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