Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Reliability Analysis of Switches and Crossings – A Case Study in Swedish Railway [PDF]
International Journal of Railway Research, 2017 It is reported that switches and crossings (S&C) are one of the subsystems that cause the most delays on Swedish Railways while accounting for at least 13% of maintenance costs.
Behzad Ghodrati +2 more
doaj
Tree LANS with collision avoidance : protocol, switch architecture, and performance [PDF]
, 1987 Packet collisions and their resolution create a performance bottleneck in random access LANs. A hardware solution to this problem is to use collision avoidance switches.
Goto, Kunio +2 more
core
Two Modes of Magnetization Switching in a Simulated Iron Nanopillar in an Obliquely Oriented Field
, 2007 Finite-temperature micromagnetics simulations are employed to study the magnetization-switching dynamics driven by a field applied at an angle to the long axis of an iron nanopillar.
+12 more
core +1 more source
Network Coding for Speedup in Switches [PDF]
, 2007 We present a graph theoretic upper bound on speedup needed to achieve 100% throughput in a multicast switch using network coding. By bounding speedup, we show the equivalence between network coding and speedup in multicast switches - i.e. network coding,
Kim, MinJi +2 more
core +5 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Highest Rank First: A New Class of Single-Iteration Scheduling Algorithms for Input-Queued Switches
IEEE Access, 2018 In this paper, we study a new class of single-iteration scheduling algorithms for inputqueued switches based on a new arbitration idea called highest rank first (HRF).
Bing Hu +3 more
doaj +1 more source
Micro-Switches with Sputtered Au, AuPd, Au-on-AuPt, and AuPtCu Alloy Electric Contacts [PDF]
, 2004 This work is the first to report on a new analytic model for predicting micro-contact resistance and the design, fabrication, and testing of microelectromechanical systems (MEMS) metal contact switches with sputtered bi-metallic (i.e.
Cortez, R. +4 more
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source