Results 81 to 90 of about 140,173 (267)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Applied SciencesIntegrated photonics is a cutting-edge field that merges optics and electronics on a single microchip, revolutionizing how we manipulate and transmit light.
Muhammad A. Butt, Xavier Mateos
doaj +1 more source
CHIMIA, 2019 The design and synthesis of molecular switches is of growing importance considering the steep increase in the production of consumer electronics in the recent years. The function of these devices is based on binary electronic circuits and can be
Daniel Čavlović, Michal Juríček
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Realization of a Photovoltaic Fed Sparse Alternating Current (AC)-Link Inverter
The Journal of Engineering Research, 2016 In this paper, a soft-switched alternating current (AC)-link buck-boost inverter with a reduced number of switches, referred to as a sparse AC-link buck-boost inverter, was designed and implemented for a photovoltaic (PV) interface. Important features of
R. Ramaprabha +3 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Grapho-analytic method of determining the minimum groove at the pivot root of symmetrical switches
Збірник наукових праць Державного університету інфраструктури та технологій: серія "Транспортні системи і технології", 2023 Switches are a barrier place in the track for setting the permissible speeds for trains on the main tracks, as they have special structural devices for branching traffic from the main track to the secondary track.
O. Oliynyk, L. Kushmar
doaj
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source