Results 31 to 40 of about 420,285 (299)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
900 V GaN-based sine-wave inverters for three-phase industrial applications
The Journal of Engineering, 2019 GaN devices are gradually getting attention within the industry along with SiC as a potential wide bandgap device. At present, there are almost no high-voltage GaN devices with voltage >650 V, which makes an inverter design difficult for a three-phase ...
Nilanjan Mukherjee +3 more
doaj +1 more source
Comprehensive review of nonisolated bridgeless power factor converter topologies
IET Circuits, Devices and Systems, 2021 The intention of this study is to provide a critical review of single‐phase nonisolated bridgeless power factor converter topologies, which will be useful for novice researchers in the power electronics field.
Ankit Kumar Singh +3 more
doaj +1 more source
A Four-Quadrant Switched Capacitor DC-DC Convertor Enabling Power-Efficient Lab-Grade Potentiostats [PDF]
2020 IEEE 20th Mediterranean Electrotechnical Conference ( MELECON), 2020 This paper presents a low-power potentiostat based on a four-quadrant switched capacitor DC-DC convertor for use in lab applications. The gearbox convertor achieves a compliance voltage of ±2.5V. Through the use of frequency scaling, the convertor features output currents in the range of 1µA to 1mA, outclassing other state-of-the-art power efficient ...
Swiggers, Matthias +4 more
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A Novel Fully Soft‐Switching DC–DC High Step‐Up Converter With Integrated Auxiliary Circuit
The Journal of EngineeringThis paper introduces a new high step‐up converter based on an interleaved structure. The topology achieves high efficiency by eliminating switching losses and reducing conduction losses.
Arsalan Erfani +2 more
doaj +1 more source
DC–DC converter with a high step-down ratio for water desalination applications
The Journal of Engineering, 2019 A single-stage 600 : 1 ratio voltage step-down dc–dc converter designed to produce a voltage of between 1 and 1.5 V from a rectified single/three-phase AC supply, for application in a desalination process, is presented. A coupled-inductor design is used,
Richard C. Pollock +3 more
doaj +1 more source
Generic spice compatible model of current feedback in switch mode convertors
Electronics Letters, 1992 The mechanism of duty cycle generation in current mode (CM) and average current mode (ACM) PWM convertors is examined and found to be identical except for the functional relationship of the controlling parameters. This result is used to develop a SPICE compatible and topology independent generic current mode (GCM) model.
S. Ben-Yaakov, Z. Gaaton
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Design of a full SiC three-phase power factor correction with an interleaved output buck converter
The Journal of Engineering, 2019 Active rectification of the three-phase grid nowadays is a central task of power electronics. However, as the necessary DC bus voltages vary, DC-DC converters are needed.
Maximilian Nitzsche +3 more
doaj +1 more source