Results 51 to 60 of about 440,289 (298)
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
, 2014 Avid Convertors in racks.https://repository.belmont.edu/ownphotos/1206/thumbnail ...
Ocean Way Nashville
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
High pulse AC/DC convertors and their application to HVDC transmission. [PDF]
, 1992 AC/DC convertors used in HVdc transmission systems inject harmonics into their associated AC and DC systems. A conventional approach to filter these harmonics is to use passive filters on both AC and DC sides of the convertor.
Villablanca, Miguel
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
SPICE simulation of quasi-resonant zero-current-switching DC-DC convertors
Electronics Letters, 1990 A simple, topology-independent method is proposed for simulating the responses of open and closed-loop quasiresonant DC-DC convertors operating in the zero-current-switching mode (ZCS-QRC). The method hinges on the substitution of the resonant network and switch assembly, fundamental in the realisation of such systems, by an equivalent circuit which ...
S. Ben-Yaakov +3 more
openaire +1 more source
New modulation scheme for bidirectional qZS modular multi-level converters
The Journal of Engineering, 2019 This study proposes a dedicated modulation scheme for a bidirectional quasi-Z-source (qZS) modular multi-level converter. The operation principle and a suitable pulse-width modulation method are proposed.
Fatma A. Khera +2 more
doaj +1 more source
Control of Dual-Opposed Stirling Convertors with Active Power Factor Correction Controllers [PDF]
, 2006 When using recently-developed active power factor correction (APFC) controllers in power systems comprised of dual-opposed free-piston Stirling convertors, a variety of configurations of the convertors and controller(s) can be considered, with ...
Lewandowski, Edward J. +2 more
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