Results 61 to 70 of about 440,289 (298)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Hybrid control approach for fast switching MMCs

The Journal of Engineering, 2019
This study presents a new hybrid control approach for different control and switching frequencies for converters of the modular multi-level converter (MMC) family.
Mathias Schnarrenberger, Dennis Bräckle, Michael Braun   +2 more
doaj   +1 more source

Design of power supply for security system

, 2023
This thesis is focused on switching power supply selection for alarm system ASSET. It describes eligible types of convertors for this specific application. It describes general design steps also.
Šmíd, Marek
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Monolithically Integrated Polarization Mode Convertors with Semiconductor Lasers

, 2014
Half and full polarization mode convertors which are monolithically integrated with semiconductor lasers are reported. A polarization mode conversion of above 40% and 88% was obtained using single and two back-to-back PMCs ...
Akbar, J., Abid, K., J.H. Marsh, Naeem, M.A., Kelly, A.E., M.A. Naeem, K. Abid, Holmes, B.M., B.M. Holmes, Marsh, J., Hutchings, D.C., A.E. Kelly, J. Akbar, D.C. Hutchings   +13 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Almost surely asymptotic stability of neutral stochastic differential delay equations with Markovian switching [PDF]

, 2008
The main aim of this paper is to discuss the almost surely asymptotic stability of the neutral stochastic differential delay equations (NSDDEs) with Markovian switching.
Yuan, Chenggui, Chenggui Yuan, Shen, Yi, Mao, Xuerong, National Natural Science Foundation of China (Funder), , EPSRC (U.K.) (Funder), EPSRC (U.K.) (Funder), , National Natural Science Foundation of China (Funder)   +7 more
core   +3 more sources

Analysis and Implementation of an Interleaved High Step‐Up Converter With Zero‐Voltage‐Switching

IET Power Electronics
In this paper, a high step‐up DC‐DC converter is presented. The input current ripple is reduced by adding the interleaving technique on the input side.
Marzieh Mohammadi Jouzdani, Omid Haghparast Naeini, Mahdi Shaneh, Tohid Nouri   +3 more
doaj   +1 more source

Non-isolated resonant link DC–DC converter for use with GaN devices

The Journal of Engineering, 2019
As new wide band-gap (WBG) devices are developed and improved, new topologies and control schemes are required to take advantage of the ultra-fast switching turn on/off speeds that are now available, without the limitations of switching losses and ...
Maria Orr, Stephen Finney, Derrick Holliday   +2 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source