Results 91 to 100 of about 295,261 (308)

Loss Jump During Loss Switch in Solving PDEs with Neural Networks

Communications in Computational Physics
Using neural networks to solve partial differential equations (PDEs) is gaining popularity as an alternative approach in the scientific computing community. Neural networks can integrate different types of information into the loss function. These include observation data, governing equations, and variational forms, etc.
Wang, Zhiwei, Zhang, Lulu, Zhang, Zhongwang, Xu, Zhi-Qin John   +3 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Measurement of Power Dissipation Due to Parasitic Capacitances of Power MOSFETs

IEEE Access, 2020
Analysis of the switching losses in a power MOSFET is crucial for the design of efficient power electronic systems. Currently, the state-of-the-art technique is based on measured drain current and drain-to-source voltage during the switching intervals ...
Utkarsh Jadli, Faisal Mohd-Yasin, Hamid Amini Moghadam, Peyush Pande, Jordan R. Nicholls, Sima Dimitrijev   +5 more
doaj   +1 more source

Voltage regulation considerations for the design of hybrid distribution transformers [PDF]

, 2014
The future substation depends on finding a way to mitigate the effects of the drawbacks of the conventional legacy by employing the efficiency of the solid state switches [1].
Alqarni, M, Darwish, M, Radi, MA
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Control and performance of a zero-current-switched three-phase inverter equipped with resonant circuits on the AC-side [PDF]

, 1996
This paper presents a zero-current-switched voltage-fed inverter equipped with resonant circuits on the AC side. The current flowing through a switching device, i.e., an IGBT is a sum of the load current and the resonant current.
Akagi, Hirofumi, Fujita, Hideaki, Ogasawara, Satoshi   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Multi-Phase Stator Current Tracking with Gradual Penalization of Commutations

Applied Sciences
Energy efficiency in drives is an important issue. In converter-supplied variable-speed drives, switching losses can amount to a significant portion of all losses.
Manuel R. Arahal, Manuel G. Satué, Juana M. Martínez-Heredia   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A New PWM Technique With Single Phase Switched-Capacitor High-Gain Multilevel Inverter for Photovoltaic Applications

IEEE Access
The modulation strategies employed in the Single-Phase Switched-Capacitor Multilevel (SC MLI) Inverter must produce waveform of superior quality while minimizing losses from switching.
Oorappan G. Murugan, Sivaraman Pandarinathan, S. A. Lakshmanan, C. Dhanamjayulu, S. M. Muyeen   +4 more
doaj   +1 more source