Results 121 to 130 of about 238,540 (305)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Fault Switching and Mode Analysis of Differential Mechanism Under Friction Load

open access: yesJixie chuandong, 2018
In order to analyze fault-switching of two input differential mechanism under conditions of acceleration and deceleration,the rigid-body dynamics formulae of planet differential mechanism are deduced theoretically when two inputs worked together and only
Liu Ting   +4 more
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

On the switching mechanism in Rose Bengal-based memory devices

open access: yes, 2007
Impedance switching has been observed in many organic devices, but the mechanism is still a matter of debate. Reliable switch devices consisting of an organic layer of Rose Bengal derivatives sandwiched in between indium tin oxide and aluminum electrodes
Cölle, Michael ,   +5 more
core   +1 more source

Guideway switching mechanism

open access: yes, 2008
According to one embodiment, a guideway switching mechanism includes an elongated section of flexible guideway coupled to a switch plate. The flexible guideway has a first end that may be coupled to a first elongated guideway and a second end that may be
Roop, Stephen S.
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

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