Optimal Control of Switching Linear Systems
A solution to the control of switching linear systems with input constraints was given in Benmerzouga (1997) for both the conventional enumeration approach and the new approach. The solution given there turned out to be not unique.
Ali Benmerzouga
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Multi-Switching Combination Synchronization of Three Fractional-Order Delayed Systems
Multi-switching combination synchronization of three fractional-order delayed systems is investigated. This is a generalization of previous multi-switching combination synchronization of fractional-order systems by introducing time-delays.
Bo Li, Yun Wang, Xiaobing Zhou
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Determining the Optimal Location for Multi-Contact Switching Systems
The paper highlights that integrating distributed power generation facilities into power supply systems for rural consumer with voltage up to 1000 volts leads to the challenges in managing the confguration of the associated electrical grids.
A. V. Vinogradov +2 more
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Dynamic Sensorless Control Approach for Markovian Switching Systems Applied to PWM DC-DC Converters with Time-Delay and Partial Input Saturation. [PDF]
Zahaf A +5 more
europepmc +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Practice and Preparation Time Facilitate System-Switching in Perceptual Categorization
Mounting evidence suggests that category learning is achieved using different psychological and biological systems. While existing multiple-system theories and models of categorization may disagree about the number or nature of the different systems, all
Sébastien Hélie
doaj +1 more source

